公开(公告)号：DE2952709A1

公开(公告)日：1981-07-16

申请号：DE2952709

申请日：1979-12-29

Applicant: BASF AG

Inventor： PUETTER HERMANN DIPL CHEM DR ,  BEWERT WOLFGANG DIPL CHEM DR

IPC: C07C46/04 ,  C07C50/10 ,  C07C45/28

公开(公告)号：DE2750661A1

公开(公告)日：1979-05-17

申请号：DE2750661

申请日：1977-11-12

Applicant: BASF AG

Inventor： NOHE HEINZ DIPL CHEM DR ,  BEWERT WOLFGANG DIPL CHEM DR ,  PUETTER HERMANN DIPL CHEM DR

IPC: C07D209/48

Abstract: Prodn. of 3,4,6-trichlorophthalimide (I) comprises treatment of 3,4,5,6-tetrachlorocyclohexadiene-1,2-dicarboxylic acid ester (II) with a base at up to 200 degrees C to give a 3,4,6-trichlorophthalate ester (III). This is then reacted at 100-200 degrees C with cpds. which release NH3 under the reaction conditions. (II) is esp. the dimethyl ester. (I) is an intermediate for pesticides, fungicides, pharmaceuticals, dyes and plastics processing auxiliaries. Provides simple method giving high yields without prodn. of byprods. or isomers.

公开(公告)号：DE2751173A1

公开(公告)日：1979-05-17

申请号：DE2751173

申请日：1977-11-16

Applicant: BASF AG

Inventor： NOHE HEINZ ,  BEWERT WOLFGANG DIPL CHEM DR ,  PUETTER HERMANN DIPL CHEM DR

IPC: C07C51/09 ,  C07C51/56 ,  C07C63/68 ,  C07D307/89

Abstract: Prodn. of 3,4,6-trichlorophthalic anhydride (I) comprises treating a 3,4,5,6-tetrachlorocyclohexadiene-1,2-dicarboxylic acid ester (II) with a base at up to 200 degrees C to give a 3,4,6-trichlorophthalate ester (III). (III) is then saponified conventionally to the diacid and this converted to (I) by heating. Esp. (II) is the dimethyl ester. (I) is an intermediate for pesticides, fungicides, pharmaceuticals, dyes and plastics processing additives. Simple process gives high yields without formation of by-prods. or isomers.

公开(公告)号：DE2748153A1

公开(公告)日：1979-05-03

申请号：DE2748153

申请日：1977-10-27

Applicant: BASF AG

Inventor： BEWERT WOLFGANG DIPL CHEM DR ,  LITTMANN WOLFGANG DIPL CHEM DR

IPC: C07C67/00 ,  C07C253/00 ,  C07C255/30 ,  C07D239/42 ,  C07D295/145

Abstract: In the prodn. of 2-methy6-4-amino-5-(formamidomethyl) pyrimidine (I), a cpd. of formula (IV) (where each R is independently H, alkyl, aryl or aralkyl or N(R)2 is a heterocyclic ring) is reacted with acetamidine. Cpds. (IV) are new and are prepd. by reacting metal salts of 2-formyl-3-formamidopropionitrile (II) with salts of the amines HN(R)2 (III). (I) is an intermediate for vitamin B1. Simple process avoids the use of toxic dimethyl sulphate. (I) is obtained in good yield, and is suitable for direct use in vitamin B1 prodn.