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公开(公告)号:FI71146B
公开(公告)日:1986-08-14
申请号:FI820529
申请日:1982-02-17
Applicant: BASF AG
Inventor: BINNIG FRITZ , MUELLER CLAUS D , RASCHACK MANFRED , PHILIPSBORN GERDA VON
IPC: A61K31/435 , A61K31/445 , A61P9/00 , A61P9/06 , C07D221/00 , C07D471/08
Abstract: Bispidine derivatives of the formula I I where R is hydrogen or amino, and their salts with physiologically tolerated acids. The compounds have antiarrhythmic properties.
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公开(公告)号:FI781872A
公开(公告)日:1978-12-14
申请号:FI781872
申请日:1978-06-12
Applicant: BASF AG
Inventor: BINNIG FRITZ , FRIEDRICH LUDWIG , HOFMANN HANS PETER , KREISKOTT HORST , MUELLER CLAUS , RASCHACK MANFRED
IPC: A61K31/435 , A61K31/445 , A61P9/06 , C07D221/00 , C07D471/08 , C07D
Abstract: Bispidine derivatives of the formula where R1 is H or C6H5, R2 is H, Cl or CF3, R3 is H, F or Cl and X is 0 or 1, and drugs which contain these compounds. The compounds are prepared by condensing N-monobenzylbispidine with appropriately substituted phenylethyl halides or by a Mannich reaction of N-benzylpiperid-4-one with appropriately substituted phenylalkylamines, followed by reduction. They exhibit mainly anti-arrhythmic action.
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公开(公告)号:FI63403C
公开(公告)日:1983-06-10
申请号:FI781872
申请日:1978-06-12
Applicant: BASF AG
Inventor: BINNIG FRITZ , FRIEDRICH LUDWIG , HOFMANN HANS PETER , KREISKOTT HORST , MUELLER CLAUS , RASCHACK MANFRED
IPC: A61K31/435 , A61K31/445 , A61P9/06 , C07D221/00 , C07D471/08
Abstract: Bispidine derivatives of the formula where R1 is H or C6H5, R2 is H, Cl or CF3, R3 is H, F or Cl and X is 0 or 1, and drugs which contain these compounds. The compounds are prepared by condensing N-monobenzylbispidine with appropriately substituted phenylethyl halides or by a Mannich reaction of N-benzylpiperid-4-one with appropriately substituted phenylalkylamines, followed by reduction. They exhibit mainly anti-arrhythmic action.
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公开(公告)号:AU8196282A
公开(公告)日:1982-09-30
申请号:AU8196282
申请日:1982-03-26
Applicant: BASF AG
Inventor: BINNIG FRITZ , MUELLER CLAUS D , RASCHACK MANFRED , PHILIPSBORN GERDA VON
IPC: A61K31/435 , A61K31/445 , A61P9/00 , A61P9/06 , C07D221/00 , C07D471/08 , A61K31/395
Abstract: Bispidine derivatives of the formula I I where R is hydrogen or amino, and their salts with physiologically tolerated acids. The compounds have antiarrhythmic properties.
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公开(公告)号:NO821018A
公开(公告)日:1982-09-28
申请号:NO821018
申请日:1982-03-26
Applicant: BASF AG
Inventor: BINNIG FRITZ , MUELLER CLAUS D , RASCHACK MANFRED , PHILIPSBORN GERDA VON
IPC: A61K31/435 , A61P9/00 , A61P9/06 , C07D471/08 , C07D
CPC classification number: C07D471/08
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公开(公告)号:NO157452C
公开(公告)日:1988-03-23
申请号:NO821018
申请日:1982-03-26
Applicant: BASF AG
Inventor: BINNIG FRITZ , MUELLER CLAUS D , RASCHACK MANFRED , PHILIPSBORN GERDA VON
IPC: A61K31/435 , A61K31/445 , A61P9/00 , A61P9/06 , C07D221/00 , C07D471/08
Abstract: Bispidine derivatives of the formula I I where R is hydrogen or amino, and their salts with physiologically tolerated acids. The compounds have antiarrhythmic properties.
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公开(公告)号:NO157452B
公开(公告)日:1987-12-14
申请号:NO821018
申请日:1982-03-26
Applicant: BASF AG
Inventor: BINNIG FRITZ , MUELLER CLAUS D , RASCHACK MANFRED , PHILIPSBORN GERDA VON
IPC: A61K31/435 , A61K31/445 , A61P9/00 , A61P9/06 , C07D221/00 , C07D471/08
Abstract: Bispidine derivatives of the formula I I where R is hydrogen or amino, and their salts with physiologically tolerated acids. The compounds have antiarrhythmic properties.
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公开(公告)号:FI820529L
公开(公告)日:1982-09-28
申请号:FI820529
申请日:1982-02-17
Applicant: BASF AG
Inventor: BINNIG FRITZ , MUELLER D CLAUS , RASCHACK MANFRED
IPC: A61K31/435 , A61K31/445 , A61P9/00 , A61P9/06 , C07D221/00 , C07D471/08 , C07D
Abstract: Bispidine derivatives of the formula I I where R is hydrogen or amino, and their salts with physiologically tolerated acids. The compounds have antiarrhythmic properties.
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公开(公告)号:DK157813C
公开(公告)日:1990-07-16
申请号:DK138982
申请日:1982-03-26
Applicant: BASF AG
Inventor: BINNIG FRITZ , MUELLER CLAUS D , RASCHACK MANFRED , PHILIPSBORN GERDA VON
IPC: A61K31/435 , A61K31/445 , A61P9/00 , A61P9/06 , C07D221/00 , C07D471/08
Abstract: Bispidine derivatives of the formula I I where R is hydrogen or amino, and their salts with physiologically tolerated acids. The compounds have antiarrhythmic properties.
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公开(公告)号:DK157813B
公开(公告)日:1990-02-19
申请号:DK138982
申请日:1982-03-26
Applicant: BASF AG
Inventor: BINNIG FRITZ , MUELLER CLAUS D , RASCHACK MANFRED , PHILIPSBORN GERDA VON
IPC: A61K31/435 , A61K31/445 , A61P9/00 , A61P9/06 , C07D221/00 , C07D471/08
Abstract: Bispidine derivatives of the formula I I where R is hydrogen or amino, and their salts with physiologically tolerated acids. The compounds have antiarrhythmic properties.
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