公开(公告)号：WO03020942A2

公开(公告)日：2003-03-13

申请号：PCT/EP0209723

申请日：2002-08-30

Applicant: BASF AG ,  HAUER BERNHARD ,  BREUER MICHAEL ,  ROGERS PETER ,  SANDFORD VANESSA ,  ROSCHE BETTINA

Inventor： HAUER BERNHARD ,  BREUER MICHAEL ,  ROGERS PETER ,  SANDFORD VANESSA ,  ROSCHE BETTINA

IPC: C12N9/88 ,  C12P7/22 ,  C12P7/26

CPC classification number: C12P7/22 ,  C12N9/88 ,  C12P7/26

Abstract: This application relates to a new process for the production of R-phenylacetylcarbinol by an enzymatic process in a liquid two-phase system.

Abstract translation: 本申请涉及通过液相两相体系中的酶法生产R-苯乙酰基甲醇的新方法。

公开(公告)号：WO2005108590A3

公开(公告)日：2006-04-06

申请号：PCT/EP2005004872

申请日：2005-05-04

Applicant: BASF AG ,  STUERMER RAINER ,  KESSELER MARIA ,  HAUER BERNHARD ,  FRIEDRICH THOMAS ,  BREUER MICHAEL ,  SCHROEDER HARTWIG

Inventor： STUERMER RAINER ,  KESSELER MARIA ,  HAUER BERNHARD ,  FRIEDRICH THOMAS ,  BREUER MICHAEL ,  SCHROEDER HARTWIG

IPC: C12P7/02 ,  C07D333/16 ,  C12N9/04 ,  C12P20060101 ,  C12P13/00 ,  C12P17/00

CPC classification number: C07D333/22 ,  C07D333/16 ,  C12P17/00

Abstract: The invention relates to a method for producing the optically active alkanols of formula (I), wherein n is an integer of from 0 to 5; Cyc represents an optionally substituted, mononuclear or polynuclear, saturated or unsaturated, carbocylic or heterocyclic ring, and R

Abstract translation: 一种用于制备式（I）其中n是从0至5的整数的光学活性链烷醇过程; Cyc为任选取代的单核或多核的，饱和或不饱和的，碳环或杂环，且R

公开(公告)号：WO2006094945A3

公开(公告)日：2007-03-15

申请号：PCT/EP2006060452

申请日：2006-03-03

Applicant: BASF AG ,  STUERMER RAINER ,  DAEUWEL JUERGEN ,  KESSELER MARIA ,  ACHATZ BRIGITTE ,  BREUER MICHAEL

Inventor： STUERMER RAINER ,  DAEUWEL JUERGEN ,  KESSELER MARIA ,  ACHATZ BRIGITTE ,  BREUER MICHAEL

IPC: C12P17/00 ,  C07C27/00 ,  C07D333/16 ,  C12P7/02 ,  C12P7/04

CPC classification number: C12P7/02 ,  C07D333/16 ,  C12P17/00 ,  C12P41/002

Abstract: The invention concerns a method for producing optically active alcohols of formula (I) by means of enzymatic reduction of the corresponding ketones, in particular, the production of (1S)-3-methylamino-1-(2-thienyl)-propane-1-ol and (1S)-3-chlorine-1-(2-thienyl)-propane-1-ol.

Abstract translation: 一种用于制备式（I）通过酶促还原相应的酮的旋光活性的链烷醇，特别是（1S）的制备-3-甲基氨基-1-（2-噻吩基）丙-1-醇和过程（1S） -3-氯-1-（2-噻吩基）丙-1-醇。

公开(公告)号：WO2006133900A9

公开(公告)日：2007-03-08

申请号：PCT/EP2006005668

申请日：2006-06-13

Applicant: BASF AG ,  BESELIN ANKE ,  ROSENAU FRANK ,  JAEGER KARL-ERICH ,  BREUER MICHAEL ,  HAUER BERNHARD

Inventor： BESELIN ANKE ,  ROSENAU FRANK ,  JAEGER KARL-ERICH ,  BREUER MICHAEL ,  HAUER BERNHARD

IPC: C12N9/52

CPC classification number: C12N9/52 ,  C12N9/20

Abstract: The invention relates to novel proteins, in particular, exhibiting a protease activity and promoting the production of extracellular lipases by bacteria, in particular, by Burkholderia-type bacteria, to coding nucleic acid sequences, expression constructs containing them, host modified thereby, to a method for producing proteins exhibiting a protease activity and to a lipase production method, in particular by Burkholderia-type bacteria.

Abstract translation: 本发明涉及的特别是伯克霍尔德氏菌属，含有这些表达构建体的核酸编码的序列，宿主经转化与之新的蛋白质，特别是具有蛋白酶活性，其通过细菌促进生产细胞外脂肪酶的，用于制备具有蛋白酶活性以及方法的蛋白质的用于生产脂酶的方法， 特别是通过伯克霍尔德氏菌属的细菌。

公开(公告)号：WO2005033094A3

公开(公告)日：2005-11-24

申请号：PCT/EP2004010939

申请日：2004-09-30

Applicant: BASF AG ,  STUERMER RAINER ,  KESSELER MARIA ,  HAUER BERNHARD ,  FRIEDRICH THOMAS ,  BREUER MICHAEL

Inventor： STUERMER RAINER ,  KESSELER MARIA ,  HAUER BERNHARD ,  FRIEDRICH THOMAS ,  BREUER MICHAEL

IPC: C07D333/16 ,  C07D333/20 ,  C12N9/04 ,  C12N15/53 ,  C12N15/63 ,  C12P7/04

CPC classification number: C07D333/16

Abstract: The invention relates to enzymatic and non-enzymatic methods for the production of 3-methylamino-1-(thiene-2-yl)-propane-1-ol; in addition to enzymes for carrying out said method; nucleic acid sequences coding for said enzymes, expression cassettes containing them, vectors and recombinant hosts.

Abstract translation: 本发明涉及酶和非酶方法对3-甲基氨基-1-（噻吩-2-基）丙-1-醇的制备; 和酶用于实施这些方法。 用于编码包含这些表达盒，载体和重组宿主核酸序列的这些酶。

公开(公告)号：WO03020921A3

公开(公告)日：2003-10-16

申请号：PCT/EP0209159

申请日：2002-08-16

Applicant: BASF AG ,  BREUER MICHAEL ,  HAUER BERNHARD ,  FRIEDRICH THOMAS

Inventor： BREUER MICHAEL ,  HAUER BERNHARD ,  FRIEDRICH THOMAS

IPC: C12N9/88 ,  C12P7/26 ,  C12P41/00

CPC classification number: C12N9/88 ,  C12P41/002

Abstract: A polypeptide with pyruvate decarboxylase activity, derived from the pyruvate decarboxylase from Zymomonas mobilis by substitution of an amino acid in position 553.

Abstract translation: 这是从运动发酵单胞的丙酮酸脱羧酶在位置第五百五十三由衍生的氨基酸取代的多肽具有丙酮酸脱羧酶活性

公开(公告)号：DE102005027685A1

公开(公告)日：2006-12-21

申请号：DE102005027685

申请日：2005-06-15

Applicant: BASF AG

Inventor： BESELIN ANKE ,  ROSENAU FRANK ,  JAEGER KARL-ERICH ,  BREUER MICHAEL ,  HAUER BERNHARD

IPC: C12N9/52 ,  C12N9/20 ,  C12N15/57

Abstract: The invention relates to novel proteins, especially with protease activity, which promote the production of extracellular lipases by bacteria, especially of the genus Burkholderia, nucleic acid sequences encoding them, expression constructs containing them, hosts transformed with them, methods for the production of the proteins with protease activity and methods for the production of lipases, especially by bacteria of the genus Burkholderia.

公开(公告)号：DE10142574A1

公开(公告)日：2003-03-20

申请号：DE10142574

申请日：2001-09-01

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  BREUER MICHAEL ,  ROGERS PETER ,  SANDFORD VANESSA ,  ROSCHE BETTINA

IPC: C12N9/88 ,  C12P7/22 ,  C12P7/26

Abstract: This application relates to a new process for the production of R-phenylacetylcarbinol by an enzymatic process in a liquid two-phase system.

公开(公告)号：AU7061201A

公开(公告)日：2002-01-14

申请号：AU7061201

申请日：2001-07-04

Applicant: BASF AG

Inventor： BREUER MICHAEL ,  HAUER BERNHARD ,  ROSCHE BETTINA ,  ROGERS PETER

IPC: C12P7/26 ,  C12R1/77

公开(公告)号：AU8732798A

公开(公告)日：1999-03-08

申请号：AU8732798

申请日：1998-07-25

Applicant: BASF AG

Inventor： BREUER MICHAEL ,  HAUER BERNHARD ,  MESCH KATHRIN ,  IDING HANS ,  GOETZ GUNTER ,  POHL MARTINA ,  KULA MARIA-REGINA

IPC: C12N9/88 ,  C12P7/26