公开(公告)号：DE59206699D1

公开(公告)日：1996-08-08

申请号：DE59206699

申请日：1992-11-24

Applicant: BASF AG

Inventor： BUEHLER VOLKER DR ,  GRABOWSKI SVEN DR ,  SANNER AXEL DR

IPC: A61K8/81 ,  A61K9/20 ,  A61K9/26 ,  A61K9/28 ,  A61Q5/06 ,  C08F2/04 ,  C08F2/06 ,  C08F2/08 ,  C08F6/12 ,  C08F218/02 ,  C08F218/08 ,  C08F220/04 ,  C08F226/10 ,  C08J3/12 ,  C08L31/04 ,  C08L39/00 ,  C08L39/04 ,  C09D131/04 ,  A61K7/06

Abstract: A process for the preparation of a redispersable, free-flowing dispersion powder of a vinylpyrrolidone-vinyl acetate copolymer containing from 15 to 40% by weight of copolymerised vinylpyrrolidone, in which the mixture of monomers is copolymerised in organic solution, the resultant solution is subjected to solvent exchange with water after addition of a surfactant, and the resultant dispersion is spray-dried or freeze-dried, the dispersion powder as such, and the use thereof for the preparation of coating compositions, glues and adhesives and in particular of the matrix and/or coating of solid pharmaceutical depot forms and of hair-spray formulations.

公开(公告)号：AT86489T

公开(公告)日：1993-03-15

申请号：AT90115636

申请日：1990-08-16

Applicant: BASF AG

Inventor： BUEHLER VOLKER DR ,  PETERSEN HERMANN DR

IPC: A23K1/16 ,  A23L33/15 ,  A61K9/16 ,  A61K31/525

公开(公告)号：AT14076T

公开(公告)日：1985-07-15

申请号：AT82102695

申请日：1982-03-31

Applicant: BASF AG

Inventor： EINIG HEINZ DR ,  BUEHLER VOLKER DR ,  KOCH WINFRIED DR ,  SCHWARZ JOACHIM ARTHUR DR

IPC: A61K9/18 ,  A61K9/22 ,  A61K9/24 ,  A61K9/52 ,  A61K9/54 ,  A61K31/275 ,  A61K31/277 ,  A61P3/00 ,  A61P3/14

公开(公告)号：DE3927810A1

公开(公告)日：1991-02-28

申请号：DE3927810

申请日：1989-08-23

Applicant: BASF AG

Inventor： BUEHLER VOLKER DR ,  PETERSEN HERMANN DR

IPC: A23L33/15 ,  A61K9/16 ,  A61K31/525 ,  A23K1/16

Abstract: Riboflavin granules contain no inactive ingredient and have a mean particle diameter of from 50 to 1,000 mu m are produced as described and used for preparing drugs and human and animal foods.

公开(公告)号：DE3447422A1

公开(公告)日：1986-06-26

申请号：DE3447422

申请日：1984-12-24

Applicant: BASF AG

Inventor： BUEHLER VOLKER DR ,  HOFMANN FRIEDBERT DR ,  HEINZ ROBERT

IPC: A61K9/14 ,  A61K9/16 ,  A61K31/375 ,  B01J2/22 ,  B01J2/00 ,  C07D307/62

Abstract: Ascorbic acid granules for direct tableting are prepared by the compacting method, wherein the ascorbic acid in the form of crystals or crystal fragments, of which not more than 40% by weight have a longest particle diameter of less than 50 mu m and not more than 15% by weight have a longest particle diameter greater than 500 mu m, and as a mixture with from 0.8 to 8% by weight of soluble polyvinylpyrrolidone having a water content of from 0.3 to 5% is compacted in a conventional manner, and the product is comminuted.

公开(公告)号：AT140015T

公开(公告)日：1996-07-15

申请号：AT92119930

申请日：1992-11-24

Applicant: BASF AG

Inventor： BUEHLER VOLKER DR ,  GRABOWSKI SVEN DR ,  SANNER AXEL DR

IPC: A61K8/81 ,  A61K9/20 ,  A61K9/26 ,  A61K9/28 ,  A61Q5/06 ,  C08F2/04 ,  C08F2/06 ,  C08F2/08 ,  C08F6/12 ,  C08F218/02 ,  C08F218/08 ,  C08F220/04 ,  C08F226/10 ,  C08J3/12 ,  C08L31/04 ,  C08L39/00 ,  C08L39/04 ,  C09D131/04 ,  A61K7/06

Abstract: A process for the preparation of a redispersable, free-flowing dispersion powder of a vinylpyrrolidone-vinyl acetate copolymer containing from 15 to 40% by weight of copolymerised vinylpyrrolidone, in which the mixture of monomers is copolymerised in organic solution, the resultant solution is subjected to solvent exchange with water after addition of a surfactant, and the resultant dispersion is spray-dried or freeze-dried, the dispersion powder as such, and the use thereof for the preparation of coating compositions, glues and adhesives and in particular of the matrix and/or coating of solid pharmaceutical depot forms and of hair-spray formulations.

公开(公告)号：DE4202193A1

公开(公告)日：1993-07-29

申请号：DE4202193

申请日：1992-01-28

Applicant: BASF AG

Inventor： GRABOWSKI SVEN DR ,  SANNER AXEL DR ,  SPERLING-VIETMEIER KARIN DR ,  BUEHLER VOLKER DR

IPC: A61K8/06 ,  A61K8/00 ,  A61K8/91 ,  A61K9/20 ,  A61K9/32 ,  A61Q5/00 ,  A61Q5/06 ,  C08F2/24 ,  C08F269/00 ,  C08F271/02

Abstract: The invention concerns the use, as film-forming agents in cosmetic and pharmaceutical preparations, of emulsion graft copolymers of polyvinyl lactams or water-soluble copolymers of ethylenically unsaturated comonomers as graft substrates and vinyl esters of C2 to C18 carboxylic acids or acrylic acid or methacrylic-acid C1 to C18 alkyl esters, or mixtures thereof, as grafter monomers.

公开(公告)号：DK0414115T3

公开(公告)日：1993-04-13

申请号：DK90115636

申请日：1990-08-16

Applicant: BASF AG

Inventor： BUEHLER VOLKER DR ,  PETERSEN HERMANN DR

IPC: A23L33/15 ,  A61K9/16 ,  A23K1/16 ,  A61K31/525

Abstract: Riboflavin granules contain no inactive ingredient and have a mean particle diameter of from 50 to 1,000 mu m are produced as described and used for preparing drugs and human and animal foods.

公开(公告)号：DE3447423A1

公开(公告)日：1986-07-03

申请号：DE3447423

申请日：1984-12-24

Applicant: BASF AG

Inventor： BUEHLER VOLKER DR

IPC: A61K9/16 ,  C07D307/62 ,  B01J2/16

Abstract: Process for the preparation of ascorbic acid granules which can be used directly for tabletting, using the fluidised-bed method, in which process the ascorbic acid, which is in the form of crystals or crystal fragments of which not more than 40% by weight have a maximum particle diameter of below 50 mu m and not more than 15% by weight have a maximum particle diameter of above 500 mu m, if appropriate as a mixture with 0.5 to 4% by weight of insoluble polyvinylpyrrolidone, is sprayed with such an amount of an aqueous solution of polyvinylpyrrolidone in a fluidised-bed granulator that the granules contain a total of 1.0 to 8% by weight of polyvinylpyrrolidone, of which at least 0.5% by weight is soluble, and simultaneously or optionally after having been sprayed, the granules are dried at 40 to 70 DEG C in such a way that the water content of the finished granules is 0.3 to 1% by weight.

公开(公告)号：DE3264519D1

公开(公告)日：1985-08-08

申请号：DE3264519

申请日：1982-03-31

Applicant: BASF AG

Inventor： EINIG HEINZ DR ,  BUEHLER VOLKER DR ,  KOCH WINFRIED DR ,  SCHWARZ JOACHIM ARTHUR DR

IPC: A61K9/18 ,  A61K9/22 ,  A61K9/24 ,  A61K9/52 ,  A61K9/54 ,  A61K31/275 ,  A61K31/277 ,  A61P3/00 ,  A61P3/14