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公开(公告)号:ZA792025B
公开(公告)日:1980-06-25
申请号:ZA792025
申请日:1979-04-27
Applicant: BASF AG
Abstract: Alkylamino-propanol derivatives of 3-alkyl-5-(2-hydroxystyryl)-isoxazole, of the general formula where R is hydrogen, alkyl of 1 to 8 carbon atoms, which is unsubstituted or substituted by hydroxyl, alkoxy of 1 to 3 carbon atoms or cycloalkyl with 3 to 8 carbon atoms in the ring, alkenyl or alkynyl of 2 to 8 carbon atoms, or cycloalkyl with 3 to 8 carbon atoms in the ring, the cycloalkyl rings being unsubstituted or mono- or di-substituted by alkyl of 1 to 3 carbon atoms, and R' is alkyl of 1 to 4 carbon atoms, and their addition salts with physiologically acceptable acids, their preparation, and pharmaceutical formulations which contain these compounds and which can be used as valuable drugs in the treatment of hypertonia, coronary diseases of the heart and cardiac arrhythmias.
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公开(公告)号:ZA78654B
公开(公告)日:1979-01-31
申请号:ZA78654
申请日:1978-02-03
Applicant: BASF AG
Inventor: FRICKEL F , HAGEN H , OHNSORGE U
IPC: C07D275/04
Abstract: The new compound 4-hydroxy-1,2-benzisothiazole and its derivatives, and their manufacture. The products are intermediates for new drugs which are useful in cardiac and circulatory disorders.
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公开(公告)号:LU78999A1
公开(公告)日:1978-06-21
申请号:LU78999
申请日:1978-02-03
Applicant: BASF AG
IPC: A61K31/428 , C07D275/04 , C07D , A61K
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公开(公告)号:ZA8100473B
公开(公告)日:1982-03-31
申请号:ZA8100473
申请日:1981-01-23
Applicant: BASF AG
Inventor: NUERRENBACH A , FRICKEL F
IPC: A61K31/41 , A61P17/00 , A61P35/00 , C07D257/04 , C07D257/06 , A61K , C07D
CPC classification number: C07D257/06 , Y10S514/863
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5.
公开(公告)号:ZA8007789B
公开(公告)日:1982-01-27
申请号:ZA8007789
申请日:1980-12-12
Applicant: BASF AG
Inventor: VON PHILIPSBORN G , FRICKEL F , LENKE D , MUELLER C
IPC: A61K31/4433 , A61K31/445 , A61P9/06 , C07D333/38 , C07D409/12 , A61K , C07C
CPC classification number: C07D333/38 , Y10S514/821
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公开(公告)号:ZA806554B
公开(公告)日:1981-11-25
申请号:ZA806554
申请日:1980-10-24
Applicant: BASF AG
IPC: A61K31/41 , A61K31/433 , A61P9/00 , A61P9/12 , A61P25/02 , C07D285/12 , A61K , C07D
Abstract: Novel aminopropanol derivatives of 2-methyl-5-(2-hydroxystyryl)-1,3,4-thiadiazole and their addition salts with acids, their preparation, pharmaceutical formulations containing these compounds, and their use as drugs in the treatment of coronary heart disease, hypertonia and cardiac arrhythmias.
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公开(公告)号:ZA78652B
公开(公告)日:1979-01-31
申请号:ZA78652
申请日:1978-02-03
Applicant: BASF AG
IPC: A61K31/428 , C07D275/04 , A61K31/425
Abstract: New aminopropanol derivatives of 4-hydroxy-1,2-benzisothiazole and their addition salts with acids, their preparation, and pharmaceutical formulations which contain the said compounds and may be used for the treatment and prophylaxis of cardiac and circulatory disorders.
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公开(公告)号:ZA8101128B
公开(公告)日:1982-03-31
申请号:ZA8101128
申请日:1981-02-20
Applicant: BASF AG
Inventor: LENKE D , FRICKEL F , GRIES J , FRANKE A , SCHLECKER R
IPC: A61K31/42 , A61P9/00 , A61P9/12 , A61P25/02 , C07D261/08 , C07D261/10 , C07D261/18 , C07F9/653 , A61K , C07D
CPC classification number: C07D261/10 , C07D261/08 , C07D261/18 , C07F9/653
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公开(公告)号:ZA8006555B
公开(公告)日:1981-11-25
申请号:ZA8006555
申请日:1980-10-24
Applicant: BASF AG
IPC: A61K31/42 , A61P9/00 , A61P9/12 , A61P25/02 , C07C43/12 , C07C45/61 , C07C45/64 , C07C45/70 , C07D261/08 , C07F9/653 , A61K , C07C
CPC classification number: C07F9/653 , C07C43/12 , C07C45/61 , C07C45/64 , C07C45/70 , C07D261/08 , C07C47/565 , C07C47/575
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公开(公告)号:ZA8006554B
公开(公告)日:1981-11-25
申请号:ZA8006554
申请日:1980-10-24
Applicant: BASF AG
IPC: A61K31/41 , A61K31/433 , A61P9/00 , A61P9/12 , A61P25/02 , C07D285/12 , A61K , C07D
CPC classification number: C07D285/12 , Y10S514/823
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