公开(公告)号：JPH05170648A

公开(公告)日：1993-07-09

申请号：JP13485192

申请日：1992-05-27

Applicant: BASF AG

Inventor： FUUBERUTO ZAUTAA ,  GIIZERA ROORENTSU ,  GERUTO SHIYUTAINAA ,  BERUNTO YANSEN ,  TEIMU ANKE ,  BUORUFUGANGU SHIYUTEEKURITSUHI

IPC: A61K31/165 ,  A61K31/215 ,  A61K31/415 ,  A61K31/42 ,  A61K31/44 ,  A61K31/505

Abstract: PURPOSE: To obtain an antifungal agent comprising a phenylacetic acid derivative. CONSTITUTION: This antifungal agent comprises 0.01-90wt.% of a compound of the formula (Y is =CH-OCH3 , =CH-CH3 , =CH-CH2 -CH3 , etc.; X is O, NH, etc.; Z is a halogen, nitro, cyano, an alkyl, an alkynyl, an aryl, etc.; U, V and W are each a halogen, H, nitro, etc.) as an active ingredient. The compound is excellent in antifungal action and is useful for treating subcutaneous mycoses and dermatomycosis caused especially by Epidermophyton, Microsporum, Trichophyton, yeast fungus Candida, filamentous fungi, etc. The antifungal agent can be pharmaceutically manufactured into a dosage form such as tablet, sugar-coated tablet capsule, pill, aqueous solution, injection, ointment, cream, paste or lotion. A dose is 1-50mg/kg in the case of oral administration.

公开(公告)号：JPH0211586A

公开(公告)日：1990-01-16

申请号：JP11239689

申请日：1989-05-02

Applicant: BASF AG

Inventor： ROOTAA DAUMU ,  GERUHARUTO KAIRUHAUAA ,  GIIZERA ROORENTSU ,  EEBERUHARUTO AMUMERUMAN ,  TEIMU ANKE ,  UORUFUGANGU UEEBAA ,  UORUFUGANGU SHIYUTEGURITSUHI ,  BERUTO SHIYUTEFUAN ,  ANGERA SHIEERAA

IPC: C12P17/18 ,  A01N43/90 ,  A61K31/335 ,  A61P31/04 ,  A61P31/12 ,  A61P35/00 ,  C07D493/10 ,  C12R1/645