公开(公告)号：DE19913699A1

公开(公告)日：2000-09-28

申请号：DE19913699

申请日：1999-03-26

Applicant: BASF AG

Inventor： SCHAEFER BERND ,  HELMCHEN GUENTER ,  KAZMAIER ULI ,  SCHLEICH SIMONE ,  STAHR HELMUT ,  WOLFART VOLKER

IPC: C07D211/78 ,  C07D207/16 ,  C07D207/20 ,  C07D211/70

Abstract: The invention relates to a method for producing compounds of the general formula (I) in which R is hydrogen, C1-C6-alkoxy, -NHC1-C6-alkyl, -N(C1-C6-alkyl)2, OH, NH2; R is hydrogen, C1-C6-alkyl, Me3Si, C1-C6-alkyl-S; R is Boc, C1-C6-acyl, mesyl, benzolsulfonyl, tosyl, trifluoroacetyl, A1-A3-peptide; n is 1, 2; and R is H, C1-C6-alkyl rest. According to said method a pyrroline or dehydropiperidine derivative of the general formula (II) is reacted with a strong base and a compound of the general formula (III), in which Y is Cl, C1-C6-alkoxy, -NHC1-C6-alkyl, -N(C1-C6-alkyl)2, N(C1-C6-alkyl) OC1-C6, where R is not equal OH, or with carbon dioxide when R = OH. The reaction product of (II) and (III) is possibly hydrolyzed or reacted with a compound of the general formula (IV) R -X, in which X is Cl, Br, I, MesO, TosO, triflate, R is hydrogen, C1-C6-alkyl, Me3Si, C1-C6-alkyl-S or NH4, or R -X is (C1-C6-alkyl-`S)2.

公开(公告)号：ZA200107629B

公开(公告)日：2002-09-17

申请号：ZA200107629

申请日：2001-09-17

Applicant: BASF AG

Inventor： SCHAEFER BERND ,  HELMCHEN GUENTER ,  KAZMAIER ULI ,  SCHLEICH SIMONE ,  STAHR HELMUT ,  WOLFART VOLKER

IPC: C07D211/78 ,  C07D207/16 ,  C07D207/20 ,  C07D211/70 ,  C07D

Abstract: A process for preparing compounds of the formula Iin whichR is hydrogen, C1-C6-alkoxy, -NHC1-C6-alkyl, -N(C1-C6-alkyl)2, OH, NH2R1 is hydrogen, C1-C6-alkyl, Me3Si, C1-C6-alkyl-SR2 is Boc, C1-C6-acyl, mesyl, benzenesulfonyl, tosyl, trifluoroacetyl, A1-A3-peptiden is 1, 2R4 is H, C1-C6-alkyl,is described.

公开(公告)号：NO20014645D0

公开(公告)日：2001-09-25

申请号：NO20014645

申请日：2001-09-25

Applicant: BASF AG

Inventor： SCHAEFER BERND ,  HELMCHEN GUENTER ,  KAZMAIER ULI ,  SCHLEICH SIMONE ,  STAHR HELMUT ,  WOLFART VOLKER

IPC: C07D211/78 ,  C07D207/16 ,  C07D207/20 ,  C07D211/70 ,  C07D207/22

Abstract: A process for preparing compounds of the formula Iin whichR is hydrogen, C1-C6-alkoxy, -NHC1-C6-alkyl, -N(C1-C6-alkyl)2, OH, NH2R1 is hydrogen, C1-C6-alkyl, Me3Si, C1-C6-alkyl-SR2 is Boc, C1-C6-acyl, mesyl, benzenesulfonyl, tosyl, trifluoroacetyl, A1-A3-peptiden is 1, 2R4 is H, C1-C6-alkyl,is described.

公开(公告)号：HU0200420A2

公开(公告)日：2002-05-29

申请号：HU0200420

申请日：2000-03-17

Applicant: BASF AG

Inventor： HELMCHEN GUENTER ,  KAZMAIER ULI ,  SCHLEICH SIMONE ,  DR SCHAEFER BERND ,  STAHR HELMUT ,  WOLFART VOLKER

IPC: C07D211/78 ,  C07D207/16 ,  C07D207/20 ,  C07D211/70 ,  C07D207/22

Abstract: A process for preparing compounds of the formula Iin whichR is hydrogen, C1-C6-alkoxy, -NHC1-C6-alkyl, -N(C1-C6-alkyl)2, OH, NH2R1 is hydrogen, C1-C6-alkyl, Me3Si, C1-C6-alkyl-SR2 is Boc, C1-C6-acyl, mesyl, benzenesulfonyl, tosyl, trifluoroacetyl, A1-A3-peptiden is 1, 2R4 is H, C1-C6-alkyl,is described.

公开(公告)号：BR0009330A

公开(公告)日：2002-01-08

申请号：BR0009330

申请日：2000-03-17

Applicant: BASF AG

Inventor： SCHOFER BERND ,  HELMCHEN GUENTER ,  KAZMAIER ULI ,  SCHLEICH SIMONE ,  STAHR HELMUT ,  WOLFART VOLKER

IPC: C07D211/78 ,  C07D207/16 ,  C07D207/20 ,  C07D211/70 ,  C07D207/22

Abstract: A process for preparing compounds of the formula Iin whichR is hydrogen, C1-C6-alkoxy, -NHC1-C6-alkyl, -N(C1-C6-alkyl)2, OH, NH2R1 is hydrogen, C1-C6-alkyl, Me3Si, C1-C6-alkyl-SR2 is Boc, C1-C6-acyl, mesyl, benzenesulfonyl, tosyl, trifluoroacetyl, A1-A3-peptiden is 1, 2R4 is H, C1-C6-alkyl,is described.

公开(公告)号：NO20014645L

公开(公告)日：2001-09-25

申请号：NO20014645

申请日：2001-09-25

Applicant: BASF AG

Inventor： SCHAEFER BERND ,  HELMCHEN GUENTER ,  KAZMAIER ULI ,  SCHLEICH SIMONE ,  STAHR HELMUT ,  WOLFART VOLKER

IPC: C07D211/78 ,  C07D207/16 ,  C07D207/20 ,  C07D211/70 ,  C07D207/22

Abstract: A process for preparing compounds of the formula Iin whichR is hydrogen, C1-C6-alkoxy, -NHC1-C6-alkyl, -N(C1-C6-alkyl)2, OH, NH2R1 is hydrogen, C1-C6-alkyl, Me3Si, C1-C6-alkyl-SR2 is Boc, C1-C6-acyl, mesyl, benzenesulfonyl, tosyl, trifluoroacetyl, A1-A3-peptiden is 1, 2R4 is H, C1-C6-alkyl,is described.

公开(公告)号：NO20014645A

公开(公告)日：2001-09-25

申请号：NO20014645

申请日：2001-09-25

Applicant: BASF AG

Inventor： SCHAEFER BERND ,  HELMCHEN GUENTER ,  KAZMAIER ULI ,  SCHLEICH SIMONE ,  STAHR HELMUT ,  WOLFART VOLKER

IPC: C07D211/78 ,  C07D207/16 ,  C07D207/20 ,  C07D211/70 ,  C07D207/22

CPC classification number: C07D211/70 ,  C07D207/20