公开(公告)号：JPH1149789A

公开(公告)日：1999-02-23

申请号：JP16829998

申请日：1998-06-16

Applicant: BASF AG

Inventor： HELMCHEN GUENTHER ,  MUERMANN CHRISTOPH DR

IPC: B01J31/24 ,  C07B53/00 ,  C07C45/50 ,  C07F9/655 ,  C07F15/00

Abstract: PROBLEM TO BE SOLVED: To obtain the subject new-ligand capable of easily reacting with transition metal compounds to form transition metal complexes useful as catalysts for selective enanthio hydrogenation reactions, isomerization reactions, etc., at low costs. SOLUTION: A new optically active diphosphine ligand of formula I [R is H, a 1-10C acyl, a 1-10C alkyl, a 2-10C alkenyl, a (substituted) aryl, a group of formula II (R -R are each a 1-10C alkyl, an aryl, an arylalkylene), etc.; R , R are each a 1-10C alkyl, a (substituted) aryl, etc.], and its borane adduct. The ligand of formula I can be reacted with a transition metal compound to form a transition metal complex used as a catalyst for selective synthesizing enantiomers, etc. The diphosphine ligand of formula I is obtained by reacting an optically active α,β-unsaturated lactone of formula III as a Michael acceptor with the anion of the compound of the formula: HP(R )2 and subsequently with a compound of the formula: Ha1P(R )2 (Hal is a halogen) and subsequently reducing the carbonyl functional group into ethylene group.

公开(公告)号：DE59609005D1

公开(公告)日：2002-05-08

申请号：DE59609005

申请日：1996-12-19

Applicant: BASF AG

Inventor： HELMCHEN GUENTHER ,  LANGER THOMAS

IPC: B01J31/18 ,  B01J31/24 ,  C07B41/02 ,  C07B53/00 ,  C07B61/00 ,  C07C29/143 ,  C07C29/145 ,  C07C33/14 ,  C07C33/20 ,  C07C33/22 ,  C07F9/50 ,  C07F15/00

Abstract: Chiral ruthenium complexes of formula RuX1X2L1L2 (I) are new. X1, X2 = anion (from halogen, 1-10 C carboxylic acid (optionally substituted by 1-3 Cl or F), methane sulphinic acid or trifluoromethane sulphinic acid; or X1+X2 = dianion of a 1,3-, 1,4- or 1,5-dicarboxylic acid; L1 = 5-6 membered cyclic ether, 5-8 C cyclic olefin, aromatic compound (optionally substituted by 1-3 alkyl), CO, PF3, isobutene or PR1R2R3; L2 = a bidentate chiral ligand of formula (III); R1R3 = alkyl, cycloalkyl, or aryl (optionally substituted by 1-3 1-4 C alkyl or 1-4 C alkoxy); R4 = alkyl, cycloalkyl or aryl (optionally substituted by 1-3 alkyl, alkoxy or halo); R5 = H or as for R4; or PR4R5 = a saturated 5-7 C ring, optionally condensed with 1 or 2 aryl; R6 = alkyl (optionally substituted by one or more OH, SH, NH, COOH, aryloxy, alkoxy, arylthio, alkylthio, acyloxy, alkoxycarbonyl, acylamino, aralkyl, heteroaralkyl, aryl or heteroaryl); R7 = H, alkyl, aryl or aralkyl; R8, R9 = H, 1-4 C alkyl or 1-4 C alkoxy; or R8+R9 complete cycloalkyl or aryl; provided that the absolute configuration of C atoms carrying R6 and R7 is independently (S) or (R).