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公开(公告)号：HU0202970A2
公开(公告)日：2002-12-28
申请号：HU0202970
申请日：2000-04-27
Applicant: BASF AG
IPC: A61K31/415 , C07D235/20 , A61K31/4184 , A61K31/422 , A61K31/427 , A61K31/437 , A61K31/4439 , A61K31/4709 , A61K31/496 , A61K31/497 , A61P3/10 , A61P9/00 , A61P13/12 , A61P19/02 , A61P25/00 , A61P25/08 , A61P25/10 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P43/00 , C07D235/18 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/04 , C07D409/04 , C07D413/04 , C07D413/14 , C07D417/04 , C07D471/04
Abstract: The present invention relates to novel benzimidazoles, their preparation and their use as inhibitors of the enzyme poly(ADP-ribose) polymerase or PARP (EC 2.4.2.30) for producing drugs.
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公开(公告)号：HU0202477A2
公开(公告)日：2002-12-28
申请号：HU0202477
申请日：2000-05-03
Applicant: BASF AG
IPC: C07D237/32 , A61K31/502 , A61P1/10 , A61P9/00 , A61P9/10 , A61P13/12 , A61P17/02 , A61P19/02 , A61P25/00 , A61P25/08 , A61P25/10 , A61P25/12 , A61P25/14 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P35/04 , A61P37/00 , A61P41/00 , A61P43/00 , C07D401/12 , C07D403/12
Abstract: The present invention relates to the use of phthalazine derivatives as inhibitors of the enzyme poly(ADP-ribose) polymerase or PARP (EC 2.4.2.30), to the use as inhibitors of PARP-homologous enzymes and, in particular, these phthalazine derivatives also show a selective inhibition of PARP-homologous enzymes.
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