公开(公告)号：HU0202477A2

公开(公告)日：2002-12-28

申请号：HU0202477

申请日：2000-05-03

Applicant: BASF AG

Inventor： HOEGER ,  KOCK ,  LUBISCH ,  SADOWSKI

IPC: C07D237/32 ,  A61K31/502 ,  A61P1/10 ,  A61P9/00 ,  A61P9/10 ,  A61P13/12 ,  A61P17/02 ,  A61P19/02 ,  A61P25/00 ,  A61P25/08 ,  A61P25/10 ,  A61P25/12 ,  A61P25/14 ,  A61P25/16 ,  A61P25/28 ,  A61P29/00 ,  A61P31/04 ,  A61P35/00 ,  A61P35/04 ,  A61P37/00 ,  A61P41/00 ,  A61P43/00 ,  C07D401/12 ,  C07D403/12

Abstract: The present invention relates to the use of phthalazine derivatives as inhibitors of the enzyme poly(ADP-ribose) polymerase or PARP (EC 2.4.2.30), to the use as inhibitors of PARP-homologous enzymes and, in particular, these phthalazine derivatives also show a selective inhibition of PARP-homologous enzymes.