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    6.
    发明专利
    未知

    公开(公告)号：DE3903992A1

    公开(公告)日：1990-08-16

    申请号：DE3903992

    申请日：1989-02-10

    Applicant: BASF AG

    Inventor： WUEST HANS-HEINER DR ,  JANSSEN BERND DR

    IPC: A61K31/12 ,  A61K8/30 ,  A61K8/33 ,  A61K8/35 ,  A61K8/40 ,  A61K8/41 ,  A61K8/46 ,  A61K8/49 ,  A61K31/135 ,  A61K31/165 ,  A61K31/19 ,  A61K31/235 ,  A61K31/275 ,  A61P17/00 ,  A61P27/02 ,  A61P29/00 ,  A61P31/04 ,  A61P35/00 ,  C07C49/225 ,  C07C49/792 ,  C07C65/36 ,  C07C65/40 ,  C07C69/76 ,  C07C69/773 ,  C07C69/92 ,  C07C69/94 ,  C07C225/18 ,  C07C255/56 ,  C07C309/73 ,  C07C311/16 ,  C07C311/21 ,  C07C311/29 ,  C07C317/24 ,  C07D295/10

    Abstract: Compounds of the general formula I in which A denotes an ethylene or methylene radical optionally substituted by a methyl, hydroxyl or oxo group, L denotes one of the groups R and R denotes hydrogen or a methyl radical, R denotes hydrogen, a hydroxyl or a C1-6-alkoxy group, R denotes hydrogen, a C1-4-alkyl radical, a halogen atom or a methoxy group, R denotes hydrogen or a methoxy group and R denotes hydrogen, a methyl or nitrile group, a C2-10-ketal group or the radicals -CHR -OR , -CHR -NR -R , -COR , in which R represents hydrogen or a C1-4-alkyl group, R represents hydrogen, a C1-4-alkyl, C1-20-alkanoyl or an optionally substituted benzoyl group, R and R represent hydrogen atoms, C1-4-alkyl, C1-6-alkanoyl or optionally substituted benzoyl groups or, together with the nitrogen atom to which they are bonded, represent a 5- or 6-membered, saturated heterocyclic radical, which apart from the nitrogen atom can additionally contain an oxygen atom, R represents hydrogen, a C1-4-alkyl group or the radicals -OR or -NR R with R denoting a hydrogen atom, a C1-8-alkyl group optionally substituted by 1 or 2 hydroxyl groups, an optionally substituted aryl group or an aralkyl group optionally substituted in the aryl moiety, and with R and R denoting hydrogen atoms, optionally substituted aralkyl or aryl groups, or R and R , together with the nitrogen to which they are bonded, denoting a 5- or 6-membered saturated heterocyclic radical, which apart from the nitrogen atom can additionally contain an oxygen atom, and R denotes a C1-4-alkyl group, and their physiologically tolerable salts, process for their preparation and medicaments and cosmetics prepared from them.

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