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公开(公告)号：WO9010006A3
公开(公告)日：1990-11-01
申请号：PCT/EP9000280
申请日：1990-02-20
Applicant: BASF AG
Inventor： DAUM LOTHAR , KEILHAUER GERHARD , SAUTER HUBERT , BERTRAM GUNDA , ANKE TIMM , WEBER WOLFGANG , STEGLICH WOLFGANG
IPC: C07D319/14 , A61K31/335 , A61K31/357 , A61P31/04 , C07D407/12 , C07D493/10
CPC classification number: C07D407/12 , C07D493/10
Abstract: β-methoxyacrylates of formula (I), in which R?1, R2 and R3¿ have the meanings given in the description, are useful for treating diseases. Their production is also described.
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公开(公告)号：ES2152310T3
公开(公告)日：2001-02-01
申请号：ES94911931
申请日：1994-03-19
Applicant: BASF AG
Inventor： JANSSEN BERND , KLING ANDREAS , MULLER STEFAN , RITTER KURT , SCHLECKER RAINER , KEILHAUER GERHARD
IPC: C07D295/08 , A61K31/34 , A61K31/341 , A61K31/357 , A61K31/36 , A61K31/40 , A61K31/403 , A61K31/41 , A61K31/42 , A61K31/421 , A61K31/4245 , A61K31/425 , A61K31/426 , A61K31/433 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/4412 , A61K31/4418 , A61K31/445 , A61K31/451 , A61K31/47 , A61K31/495 , A61K31/496 , A61P35/00 , C07D207/32 , C07D207/333 , C07D209/52 , C07D211/14 , C07D213/30 , C07D215/14 , C07D261/08 , C07D261/18 , C07D263/14 , C07D263/32 , C07D271/06 , C07D271/10 , C07D277/24 , C07D285/12 , C07D295/092 , C07D307/42 , C07D307/58 , C07D317/58 , C07D317/66 , C07D333/06 , C07D333/16 , C07D413/12 , C07D417/12 , C07D521/00 , C07F9/6509
Abstract: This invention relates to 1-amino-3-phenoxy-propane-derivatives of formula 1: 1 (in which A, B, R, Rx, X and Z are defined as in the specification described) and methods for their preparation. These compounds may be used as modulators of multidrug resistance in cancer chemotherapy and for circumvention of resistance in the treatment of malaria.
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公开(公告)号：DE69410614T2
公开(公告)日：1998-09-24
申请号：DE69410614
申请日：1994-08-08
Applicant: BASF AG
Inventor： KEILHAUER GERHARD , ROMERDAHL CYNTHIA , FERNANDEZ BRANA MIGUEL , QIAN XIAO-DONG , BOUSQUET PETER , CASTELLANO BERLANGA JOSE , MORAN MOSET MARINA , PEREZ DE VEGA MARIA
IPC: A61K31/47 , A61K31/473 , A61P35/00 , C07D221/14 , A61K31/435
Abstract: Disclosed herein are compounds pharmaceutical compositions containing same of the formula 1. A compound of the Formula wherein X, X', X'' and X''', A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical compositions containing same can be used in the treatment of cancer.
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公开(公告)号：ES2116612T3
公开(公告)日：1998-07-16
申请号：ES94924854
申请日：1994-08-08
Applicant: BASF AG
Inventor： KEILHAUER GERHARD , ROMERDAHL CYNTHIA , FERNANDEZ BRANA MIGUEL , QIAN XIAO-DONG , BOUSQUET PETER , CASTELLANO BERLANGA JOSE MARIA
IPC: A61K31/47 , A61K31/473 , A61P35/00 , C07D221/14 , A61K31/435
Abstract: Disclosed herein are compounds pharmaceutical compositions containing same of the formula 1. A compound of the Formula wherein X, X', X'' and X''', A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical compositions containing same can be used in the treatment of cancer.
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公开(公告)号：HRP940458A2
公开(公告)日：1997-06-30
申请号：HRP940458
申请日：1994-08-11
Applicant: BASF AG
Inventor： KEILHAUER GERHARD , ROMERDAHL CYNTHIA , BRANA MIGUEL FERNANDEZ , QUIAN XIAO-DONG , BOSQUET PETER , BERLANGA JOSE MARIA CASTELLANO , MOSET MARINA MORAN , VEGA MARIA JESUS PEREZ DE
IPC: A61K31/47 , A61K31/473 , A61P35/00 , C07D221/14 , C07D211/14 , A61K31/435
Abstract: Disclosed herein are compounds pharmaceutical compositions containing same of the formula 1. A compound of the Formula wherein X, X', X'' and X''', A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical compositions containing same can be used in the treatment of cancer.
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Patent Agency Ranking
公开(公告)号：SI9420053A
公开(公告)日：1996-08-31
申请号：SI9420053
申请日：1994-08-08
Applicant: BASF AG
Inventor： KEILHAUER GERHARD , ROMERDAHL CYNTHIA , FERNANDEZ BRANA MIGUEL , QIAN XIAO-DONG , BOUSQUET PETER , CASTELLANO BERLANGA JOSE MARIA , MORAN MOSET MARINA , PEREZ DE VEGA MARIA JESUS
IPC: A61K31/47 , A61K31/473 , A61P35/00 , C07D221/14 , A61K31/435
Abstract: Disclosed herein are compounds pharmaceutical compositions containing same of the formula 1. A compound of the Formula wherein X, X', X'' and X''', A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical compositions containing same can be used in the treatment of cancer.
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公开(公告)号：NO960632L
公开(公告)日：1996-02-16
申请号：NO960632
申请日：1996-02-16
Applicant: BASF AG
Inventor： KEILHAUER GERHARD , ROMERDAHL CYNTHIA , BRANA MIGUEL FERNANDEZ , QIAN XIAO-DONG , BOUSQUET PETER , BERLANGA JOSE MARIA CASTELLANO , MOSET MARINA MORAN , VEGA MARIA JESUS PEREZ DE
IPC: A61K31/47 , A61K31/473 , A61P35/00 , C07D221/14 , A61K31/435
Abstract: Disclosed herein are compounds pharmaceutical compositions containing same of the formula 1. A compound of the Formula wherein X, X', X'' and X''', A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical compositions containing same can be used in the treatment of cancer.
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公开(公告)号：NO952366L
公开(公告)日：1995-06-15
申请号：NO952366
申请日：1995-06-15
Applicant: BASF AG
Inventor： HAUPT ANDREAS , JANSSEN BERND , RITTER KURT , KLINGE DAGMAR , KEILHAUER GERHARD , ROMERDAHL CYNTHIA , BARLOZZARI TERESA , QIAN XIAO-DONG
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公开(公告)号：NO952366A
公开(公告)日：1995-06-15
申请号：NO952366
申请日：1995-06-15
Applicant: BASF AG
Inventor： HAUPT ANDREAS , JANSSEN BERND , RITTER KURT , KLINGE DAGMAR , KEILHAUER GERHARD , ROMERDAHL CYNTHIA , BARLOZZARI TERESA , QIAN XIAO-DONG
IPC: A61K38/00 , A61K38/08 , A61P35/00 , C07K1/00 , C07K5/02 , C07K5/027 , C07K7/02 , C07K7/06 , A61K38/05 , A61K38/06 , A61K38/07
CPC classification number: C07K7/02 , A61K38/00 , C07K5/0205
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公开(公告)号：SI9300661A
公开(公告)日：1994-06-30
申请号：SI9300661
申请日：1993-12-16
Applicant: BASF AG
Inventor： HAUPT ANDREAS , JANSSEN BERND , RITTER KURT , KLINGE DAGMAR , KEILHAUER GERHARD , ROMERDAHL CYNTHIA , BARLOZZARI TERESA , QIAN XIAO-DONG
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