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    New peptides.
    1.
    发明专利
    New peptides. 未知

    公开(公告)号：PL178351B1

    公开(公告)日：2000-04-28

    申请号：PL30620893

    申请日：1993-05-10

    Applicant: BASF AG

    Inventor： HAUPT ANDREAS ,  EMLING FRANZ ,  ROMERDAHL CYNTHIA

    IPC: C07K5/10 ,  C07K7/06

    Abstract: 1. The peptide with the formula I where: R1> refers to a C1-7-alkyl group, C3-6-cycloalkyl group, R2> refers to an atom of hydrogen, C1-4-alkyl group, R1>-N-R2> together refer to an N-pyrrolidinyl group, A refers to valyl radical, isoleucil radical, 2-tert-butyl-glycil radical or 2-ethyl-glycil radical, B refers to N-methyl- or N-ethyl-valyl radical, norvalyl, leucil, isoleucil, 2-tert-butyl-glycol, 3-tert-butyl-alanyl radical, D and E refer to a radical selected independently from the group of radicals: prolyl, homo-prolyl, hydroxy-prolyl or thiazolidinyl-4-carbonyl; F and G refer to a radical selected independently from the group of radicals: valyl, 2-tert-butyl-glycil, isoleucil, leucil, 3-cyclohexyl-alanyl, phenyl-alanyl, N-methyl-phenyl-alanyl, tetra-hydro-iso-quinolyl-2-carbonyl, 1-aminoindole-1-carbonyl and 3-naphthyl-alanyl, X refers to a C1-5-alkyl group, v and w are independently equal to 0 or 1, while K refers to OH group, C1-7-alkoxyl group, phenoxyl group, or an amino radical with the formula R5>-N-R6>, where: R5> refers to an atom of hydrogen, or a hydroxyl group or a C1-7-alkoxyl group or benzyloxyl group or C1-7-alkyl group or fluorine-alkyl group or C3-7-cycloalkyl group or benzyl group, which can be substituted with three substituents at most, while the substituents may refer independently to CF3, nitric group, C1-7-alkyl-sulphonyl group, C1-4-alkoxyl group, phenoxyl group, benzoxyl group, a halogen or a C1-4-alkyl group; R6> refers to an atom of hydrogen or C1-7-alkyl group C3-7-cycloalkyl group or fluorine-alkyl group or phenyl group, which can be substituted with three substituents at most, while the substituents may refer independently to a CF3 group, nitric group, C1-4-alkyl group - which can form a cyclical configuration - C1-4-alkoxyl group, phenoxyl group, benzoxyl group or C1-7-alkyl-sulphonyl group...

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