公开(公告)号：DE19840069A1

公开(公告)日：2000-03-09

申请号：DE19840069

申请日：1998-09-03

Applicant: BASF AG

Inventor： FRIEDRICH THOMAS ,  BEWERT WOLFGANG ,  LUEDDECKE ERIK ,  KLINGLER JUERGEN ,  HEGER ROBERT

IPC: A23K20/174 ,  A23K20/189 ,  A23K40/30 ,  A23L33/15 ,  C12N9/06 ,  C07K7/08 ,  A61K38/43 ,  C07K7/06

Abstract: A method to manufacture a preparation of an active substance is new, where the active substance is surrounded by at least one layer consisting of a protein that is cross-linked by an enzyme chosen from the group of lipoxygenase, protein disulfide isomerase, phenol oxidase and peroxidase, lysyl oxidase, protein disulfide reductase, tyrosine oxidase or sulfhydryl oxidases. Independent claims are also included for: (1) an active substance preparation prepared by a method as above; and (2) an isolated protein comprising at least one of the 12 sequences given in the specification.

公开(公告)号：DE19840489A1

公开(公告)日：2000-03-09

申请号：DE19840489

申请日：1998-09-04

Applicant: BASF AG

Inventor： FRIEDRICH THOMAS ,  BEWERT WOLFGANG ,  LUEDDECKE ERIK ,  KLINGLER JUERGEN ,  HEGER ROBERT

IPC: A23B5/00 ,  A23K20/174 ,  A23K20/179 ,  A23K20/189 ,  A23K40/30 ,  A23L33/15 ,  A23P10/30 ,  A61K9/16 ,  C12N9/06 ,  C07K7/08 ,  A23K1/16 ,  A23L1/30 ,  A61K31/07 ,  A61K31/366 ,  A61K31/592

Abstract: An enzyme (I) selected from lipoxygenases, protein disulfide isomerases, phenol oxidases and peroxidases, lysyl oxidases, protein disulfide reductases, tyrosine oxidases or sulfhydryl oxidases is used to formulate compositions containing active ingredients. Independent claims are also included for the following: (1) a process for producing compositions in which one or more active ingredients are surrounded by at least one layer, where at least part of at least one layer comprises a protein that has been crosslinked with (I). (2) a composition in which at least part of at least one layer surrounding one or more active ingredients comprises a protein that has been crosslinked with (I); (3) an isolated protein comprising at least one of amino acid sequences (II)-(XIII): (a) G(S)(C)Q(C)KTNEKVNIEAPKPNI(C)DT(L)(S) (b) EYP(C)APDVVYNTK (c) GGTYSTVTQNPTLNR (d) DYNIMPGGGXVHR (e) ATGGTYSTVXAQN (f) APETENNAR (g) GPL(P)VNE(E)TTIEPLSFYNT (h) IYELSLQELIAEYGSDDPNNQHTFYSDI (i) DNVDDLSCTIIQR (j) VAPETENCAR (k) NVDVEYPCAPGVVYNTK (l) GYPNAEY(S)LDF/ER, in which lysine iota -amino groups are optionally oxidized to aldehyde groups; and (4) a food or animal feed containing the composition of (2).

公开(公告)号：DE19909351A1

公开(公告)日：2000-09-07

申请号：DE19909351

申请日：1999-03-03

Applicant: BASF AG

Inventor： SCHROF WOLFGANG ,  KLINGLER JUERGEN ,  HORN DIETER

IPC: G01J3/28 ,  G01J3/44 ,  G01J3/457 ,  G01N21/65