New di:alkoxy-substituted pyrazine derivs. - useful as amino acid and di:peptide intermediates

    公开(公告)号:DE3928510A1

    公开(公告)日:1991-03-07

    申请号:DE3928510

    申请日:1989-08-29

    Applicant: BASF AG

    Abstract: Dialkoxy-pyrazine derivs. (I) are new. R1 = methyl and R2 = methyl or R1 = ethyl and R2 = methyl; R3 = methyl, ispropyl, isobutyl, sec.butyl, tert.butyl or benzyl. Prepn. of (I) is by reaction of (II) with HNR5R6 and a Lewis acid to give (III) followed by hydrolysis of prod. (III) and 6-alkylation. R5 = H or 1-6 alkyl. The 6-alkylation is carried out using a trimethyl-or triethyl-oxonium tetrafluoro -borate. USE/ADVANTAGE - Cpds. (I) are intermediates for amino acids and dipeptides. Cpds. (I) are more suitable as intermediates than the symmetrical dialkoxy-pyraxines described in DE 2934252.

    4.
    发明专利
    未知

    公开(公告)号:DE58907247D1

    公开(公告)日:1994-04-21

    申请号:DE58907247

    申请日:1989-09-09

    Applicant: BASF AG

    Abstract: PCT No. PCT/EP89/01050 Sec. 371 Date Jul. 17, 1990 Sec. 102(e) Date Jul. 17, 1990 PCT Filed Sep. 9, 1989 PCT Pub. No. WO90/03386 PCT Pub. Date Apr. 5, 1990.Process for producing dipeptides from non-proteinogenic amino acids with terminal carbon atoms.

Patent Agency Ranking