公开(公告)号：BG63304B1

公开(公告)日：2001-09-28

申请号：BG10190897

申请日：1997-09-24

Applicant: BASF AG

Inventor： MERKELE HANS R ,  FRETSCHNER ERICH ,  SCHROEDER JUERGEN

IPC: C07D231/12 ,  C07D521/00

Abstract: A process is disclosed for preparing N-substituted pyrazoles having the general formula in which R1 stands for C1 to C12 alkyl or C7 to C20 phenylalkyl, and R2, R3, R4 represent independently from each other hydrogen, C1 to C12 alkyl, C7 to C20 phenylalkyl or optionally substituted aryl residues, by reacting pyrazoles having the general formula 10 claims in which R2, R3 and R4 have above-said meanings, with an alcohol having the general formula R1-O-H, in which R1 has above-said meanings, at temperatures from 50 to 400oC in the presence of a catalyst. The reaction of pyrazole (II) with compound (III) is carried out in a molar ratio from 0.001:1 to 1: 1 in the liquid phase at a slight negative pressure up to an over pressure of 250 bars. Acids. their alkyl esters and/or their anhydrides are used as catalysts in a molar ratio from 0.0001: 1 to 0.5: 1 in relation to pyrazole (II). 10 claims

公开(公告)号：BG101908A

公开(公告)日：1998-05-29

申请号：BG10190897

申请日：1997-09-24

Applicant: BASF AG

Inventor： MERKELE HANS R ,  FRETSCHNER ERICH ,  SCHROEDER JUERGEN

IPC: C07D231/12 ,  C07D521/00

Abstract: A process is disclosed for preparing N-substituted pyrazoleshaving the general formulain which R1 stands for C1 to C12 alkyl or C7 to C20 phenylalkyl,and R2, R3, R4 represent independently from each other hydrogen,C1 to C12 alkyl, C7 to C20 phenylalkyl or optionally substitutedaryl residues, by reacting pyrazoles having the general formulain which R2, R3 and R4 have above-said meanings, with an alcoholhaving the general formulaR1-O-H, in which R1 has above-said meanings, at temperatures from50 to 400oC in the presence of a catalyst. The reaction ofpyrazole (II) with compound (III) is carried out in a molar ratiofrom 0.001:1 to 1: 1 in the liquid phase at a slight negativepressure up to an over pressure of 250 bars. Acids. their alkylesters and/or their anhydrides are used as catalysts in a molarratio from 0.0001: 1 to 0.5: 1 in relation to pyrazole (II).10 claims