公开(公告)号：CZ20031978A3

公开(公告)日：2004-06-16

申请号：CZ20031978

申请日：2002-01-19

Applicant: BASF AG

Inventor： HERMANN THERON ,  PATTERSON A THOMAS ,  PERO JANICE G ,  YOCUM R ROGERS ,  BALDENIUS KAI-UWE ,  BECK CHRISTINE

IPC: C12N15/09 ,  A61K31/7088 ,  A61P43/00 ,  C12N1/21 ,  C12N9/10 ,  C12P13/00 ,  C12P13/02 ,  C12P13/04 ,  C12R1/125

Abstract: The present invention features improved methods for producing pantoate and pantothenate utilizing microorganisms having modified pantothenate biosynthetic enzyme activities. In particular, the invention features methods for reducing byproduct formation and increasing yields and purity of desired product. Recombinant microorganisms and conditions for culturing same are also are featured. Also featured are compositions produced by such microorganisms.