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公开(公告)号:DE2631780A1
公开(公告)日:1978-01-19
申请号:DE2631780
申请日:1976-07-15
Applicant: BASF AG
Inventor: LAEMMERHIRT LAUS DR , PICH CLAUS HINRICH DR , SEELERT KURT DR
IPC: A61K9/08 , A61K9/00 , A61K31/635 , A61K47/32 , A61K31/505
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公开(公告)号:DE2439196A1
公开(公告)日:1976-02-26
申请号:DE2439196
申请日:1974-08-16
Applicant: BASF AG
Inventor: HERRLE KARL DR , DENZINGER WALTER , SEELERT KURT DR
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公开(公告)号:CH619472A5
公开(公告)日:1980-09-30
申请号:CH1069575
申请日:1975-08-15
Applicant: BASF AG
Inventor: HERRLE KARL DR , DENZINGER WALTER , SEELERT KURT DR , SCHWARZ WOLFGANG DR
IPC: A61K31/18 , A61K31/785 , A61K31/79 , A61K33/18 , C08F8/00 , C08F8/20 , C08F126/10 , C08F8/22 , A01N43/36
Abstract: Polyvinylpyrrolidone-iodine, manufactured by reaction of iodine and a polyvinylpyrrolidone obtained by polymerization in an anhydrous organic solvent in the presence of a source of free radicals and optionally in the presence of a heavy metal of atomic number from 23 to 29, in the form of a complex compound or of a salt with an organic acid, as a co-activator, followed by steam distillation of this polyvinylpyrrolidone, if appropriate. The PVP-iodine of the invention is very stable and can be used as a disinfectant.
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公开(公告)号:CH617214A5
公开(公告)日:1980-05-14
申请号:CH1055675
申请日:1975-08-13
Applicant: BASF AG
Inventor: HERRLE KARL DR , DENZINGER WALTER DIPL ING , SEELERT KURT DR
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公开(公告)号:CH633181A5
公开(公告)日:1982-11-30
申请号:CH195078
申请日:1978-02-22
Applicant: BASF AG
Inventor: SCHNEIDER KURT DR , SEELERT KURT DR , LANG SIEGFRIED DR
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公开(公告)号:DE2631779A1
公开(公告)日:1978-01-19
申请号:DE2631779
申请日:1976-07-15
Applicant: BASF AG
Inventor: LAEMMERHIRT KLAUS DR , PICH CLAUS HINRICH DR , SEELERT KURT DR
IPC: A61K9/00 , A61K31/635 , A61K47/32 , A61K9/08 , A61K31/505
Abstract: New clear, aq. sulphonamide/trimethoprim solns. contain (a) a water-soluble sulphonamide salt, (b) trimethoprim and (c) polyvinyl pyrrolidone with a K-value of 10-18 in water, opt. with the addition of further substances and/or solvents. Sulphonamide/trimethoprim solns. are provided for oral, parenteral or external application. The new solns. avoid the need for solvents with poor pharmaceutical acceptability (e.g., propylene glycol, glycerine formal, dimethylacetamide). The solns. also avoid extreme of pH (which can cause local pain on injection). Typical formulation contains 4 g. sulphamoxole sodium, 0.8 g. trimethoprim, 55 g. polyvinyl pyrrolidone (K-value 12), 0.8 g. sodium sulphite and water for injection to 100 ml.
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公开(公告)号:DE2439197A1
公开(公告)日:1976-02-26
申请号:DE2439197
申请日:1974-08-16
Applicant: BASF AG
Inventor: HERRLE KARL DR , DENZINGER WALTER , SEELERT KURT DR , SCHWARZ WOLFGANG DR
IPC: C08F8/22 , C08F126/10
Abstract: Polyvinyl pyrrolidone-I2, (A), is prepd. by mixing (a) a polyvinyl pyrrolidone, (I) prepd. by polymerisation in an anhydrous organic solvent, esp. isopropanol, in the presence of a radical former and opt. of a complex cpd. of a heavy metal having atomic no. 23-29 or a salt thereof with an organic acid as coactivator, and (b) I2. (A), which have disinfectant, bactericidal, fungicidal and disinfectant properties, can be used in pharmaceutical compsns. opt. contg. H2O2; also in soap solns., shampoos, powders, gels and sprays.
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公开(公告)号:CH501725A
公开(公告)日:1971-01-15
申请号:CH260168
申请日:1968-02-22
Applicant: BASF AG
Inventor: RUTZ WALTER DR , SEELERT KURT DR , PLOETZ ERNST DR
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