3.
    发明专利
    未知

    公开(公告)号:DE2835439A1

    公开(公告)日:1980-02-28

    申请号:DE2835439

    申请日:1978-08-12

    Applicant: BASF AG

    Abstract: 2-(o-Hydroxyphenyl)-pyrrole and a process for its preparation, wherein o-benzyloxybenzoic acid allylamide is reacted with phosgene in an inert solvent, the resulting imide-chloride is cyclized in the presence of a strong sterically hindered base and the benzyl protective group is then removed by hydrogenolysis. 2-(o-Hydroxyphenyl)-pyrrole is a valuable intermediate for the synthesis of drugs. In particular, alkylamino-hydroxypropyl ethers thereof can, because of their beta -sympatholytic actions, be used for the treatment of coronary cardiac diseases, cardiac arrhythmias and hypertonia.

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