公开(公告)号：DE3064073D1

公开(公告)日：1983-08-18

申请号：DE3064073

申请日：1980-02-14

Applicant: BASF AG

Inventor： KROPP RUDOLF ,  THOEMEL FRANK DR ,  NUERRENBACH AXEL DR ,  HOFFMANN WERNER DR ,  WENISCH FRANZ DR ,  FUCHS HARTWIG

IPC: C07C45/00 ,  C07C45/69 ,  C07C49/517 ,  C07C67/00 ,  C07D307/20 ,  C07D309/12 ,  C07D311/74 ,  C07D311/94

Abstract: The preparation of bicyclic enol-ethers (I) (I) (where n is from 3 to 12, and R1, R2 and R3 may be H or C1-C4-alkyl) by free radical adduct formation of CHR1 =CR2-CHR3-O-R4 (III)(where R4 is tert.-butyl, tetrahydrofuran-2-yl or tetrahydropyran-2-yl) with a cyclic ketone (IV) (IV) followed by acid-catalyzed cyclization, and novel compounds II (II) The compounds (I) and (II) are intermediates for the synthesis of musk-like fragrances.

公开(公告)号：DE3739149A1

公开(公告)日：1989-06-01

申请号：DE3739149

申请日：1987-11-19

Applicant: BASF AG

Inventor： ZEIDLER ADOLF DR ,  THOEMEL FRANK DR ,  SCHOLZ HERBERT DR ,  WOERZ OTTO DR ,  KOOB KNUT DR ,  THIELE HEINO DR ,  KRADER THOMAS DR

IPC: C07C67/00 ,  C07C271/06 ,  C07C325/00 ,  C07C333/16

公开(公告)号：DE3160487D1

公开(公告)日：1983-07-28

申请号：DE3160487

申请日：1981-07-04

Applicant: BASF AG

Inventor： THOEMEL FRANK DR ,  HOFFMANN WERNER DR ,  DEGNER DIETER DR

IPC: A61K8/49 ,  A61Q17/04 ,  C07D307/58 ,  A61K7/42

公开(公告)号：DE3060473D1

公开(公告)日：1982-07-15

申请号：DE3060473

申请日：1980-09-10

Applicant: BASF AG

Inventor： THOEMEL FRANK DR ,  HOFFMANN WERNER DR

IPC: C11B9/00 ,  C11D3/50 ,  C07C121/34 ,  A61K7/46 ,  C07C120/00

公开(公告)号：DE3262975D1

公开(公告)日：1985-05-15

申请号：DE3262975

申请日：1982-06-30

Applicant: BASF AG

Inventor： DEGNER DIETER DR ,  HOFFMANN WERNER DR ,  THOEMEL FRANK DR

IPC: C07D315/00 ,  C25B3/25 ,  C25B3/04

Abstract: Cyclopentadecanolide of the formula I I is prepared by a process wherein 12-oxocyclopentadecanolide of the formula II is reduced electrochemically.

公开(公告)号：DE3260932D1

公开(公告)日：1984-11-15

申请号：DE3260932

申请日：1982-04-08

Applicant: BASF AG

Inventor： THOEMEL FRANK DR ,  HOFFMANN WERNER DR

IPC: C07C37/06 ,  C07C37/07 ,  C07C39/08 ,  C07C41/00 ,  C07C41/01 ,  C07C43/205 ,  C07C43/23 ,  C07C67/30 ,  C07C69/84 ,  C07C69/88 ,  C07C69/92 ,  C07C255/53 ,  C11B9/00 ,  C07C121/75 ,  C07C120/00 ,  A61K7/46

Abstract: A process for the preparation of resorcinol derivatives of the general formula I (I) where R1 is carbalkoxy, nitrile, alkyl or H and R2 to R5 are H or lower alkyl, by reacting the corresponding cyclohexane-1,3-dione (II) with oxygen or an oxygen-containing gas in the presence of a catalytic amount of a copper compound and of from 1 to 10 moles of a hydrogen halide, or from 0.5 to 5 moles of thionyl chloride per mole of II, in an alkanol having from 1 to 6 carbon atoms, tetrahydrofuran or methyl tert.-butyl ether as the solvent, at from 0 DEG to 150 C., without the addition of a significant amount of water to the reaction mixture. Some of the resorcinol derivatives prepared are useful scents with fragrance notes of the character of the odoriferous substance of natural oak moss.

公开(公告)号：DE3060939D1

公开(公告)日：1982-11-18

申请号：DE3060939

申请日：1980-05-16

Applicant: BASF AG

Inventor： HOFFMANN WERNER DR ,  THOEMEL FRANK DR

IPC: C07D309/20 ,  C07D309/22 ,  C11B9/00 ,  A61K7/46

Abstract: 2-(1-methyl-eth-1-en-1-yl)-,2-(1-methyl-prop-1-en-1-yl)-, 2-(eth-1-en-1-yl)- and 2-(prop-1-en-1-yl)-4-methyl-2,3-dihydro-6H-pyrans substituted in the 2-position of the side chain by hydroxymethyl, acyloxymethyl, alkoxycarbonylmethyl, halomethyl or formyl. The novel 4-methyl-2,3-dihydro-6H-pyrans are obtained by reaction of 3-methyl-but-3-en-1-ol with an appropriately substituted unsaturated aldehyde in the presence of an acid catalyst. The products possess very interesting organoleptic properties.

公开(公告)号：DE3361151D1

公开(公告)日：1985-12-12

申请号：DE3361151

申请日：1983-04-11

Applicant: BASF AG

Inventor： THOEMEL FRANK DR ,  HOFFMANN WERNER DR

IPC: C07C46/00 ,  B01J23/00 ,  B01J23/72 ,  B01J27/122 ,  B01J31/02 ,  C07B61/00 ,  C07C37/07 ,  C07C39/07 ,  C07C45/00 ,  C07C46/02 ,  C07C46/04 ,  C07C46/06 ,  C07C46/08 ,  C07C46/10 ,  C07C50/02 ,  C07C50/04 ,  C07C67/00

Abstract: Trimethyl-p-benzoquinone of the formula I (I) is prepared by a process wherein A. 2,5,6-trimethylcyclohex-2-en-1-one or 2,3,6-trimethylcyclohex-2-en-1-one is reacted with air or oxygen at from 0 DEG to 150 DEG C. in a virtually anhydrous low molecular weight alkanol in the presence of a catalytic amount of copper(I) oxide or copper(II) oxide and in the presence of from 1 to 10 moles of a hydrogen halide gas per mole of trimethylcyclohexenone, and thereafter B. the reaction mixture, which essentially contains 2,3,6-trimethylphenol and/or 4-halo-2,3,6-trimethylphenol, is mixed with an alkali metal alcoholate in an amount such that a sample, when moistened with water, has a pH of from 3 to 6, and is then reacted with air, pure oxygen or tert.-butyl hydroperoxide at from 0 DEG to 150 DEG C., or wherein from 1 to 10 mole equivalents of a hydrogen halide gas per mole of substrate to be reacted are passed into a mixture containing a virtually anhydrous low molecular weight alkanol and a catalytic amount of copper(I) oxide or copper(II) oxide at from 0 DEG to 30 DEG C., an alkali metal alcoholate is added in an amount such that a sample, when moistened with water, has a pH of from 3 to 6, about one mole equivalent of 2,3,6-trimethylphenol is added and the mixture is then reacted with air, oxygen or tert.-butyl peroxide at from 0 DEG to 150 DEG C. Trimethyl-p-benzoquinone is an important intermediate for the synthesis of vitamin E.

公开(公告)号：DE2961941D1

公开(公告)日：1982-03-11

申请号：DE2961941

申请日：1979-03-30

Applicant: BASF AG

Inventor： THOEMEL FRANK DR ,  HOFFMANN WERNER DR

IPC: C07C29/128 ,  C07C33/03 ,  C07C67/04 ,  C07C69/07 ,  C11B9/00

公开(公告)号：DE2960271D1

公开(公告)日：1981-05-07

申请号：DE2960271

申请日：1979-07-06

Applicant: BASF AG

Inventor： HOFFMANN WERNER DR ,  THOEMEL FRANK DR

IPC: C07C13/16 ,  C07C13/20 ,  C07C29/09 ,  C07C33/05 ,  C07C33/14 ,  C09D7/12 ,  C11B9/00 ,  C11D3/50 ,  A61K7/46