公开(公告)号：GB823025A

公开(公告)日：1959-11-04

申请号：GB1945458

申请日：1958-06-18

Applicant: BASF AG

Inventor： SCHOELLER CONRAD ,  ZIPF HANS FRIEDRICH ,  SCHOETENSACK WOLFGANG ,  BLECHSCHMIDT WOLFGANG

IPC: A61K31/765

Abstract: A polyglycol ether derivative which contains 6-12 ethoxy groups is prepared from an aliphatic alcohol, carboxylic acid, amine or amide which contains 6-14 carbon atoms by reaction with ethylene oxide or a polyglycol ether of the formula HO(CH2-CH2-O)nH wherein n is 6 to 12. Suitable polyglycol ether derivatives are those of dodecyl, octyl, iso-octyl, nonyl and decyl alcohols, dodecylamine, oleylamine, lauric acid amide, lauryl ethanolamide, dodecylamide, iso-octylamine, lauric and undecylenic acids.ALSO:A cough remedy comprises a polyglycol ether derivative containing 6-12 ethoxy groups of an aliphatic alcohol, carboxylic acid, amine or amide which contains from 6-14 carbon atoms (for preparation see Group IV (b)). Specified polyglycol ether derivatives are dodecyl nonaglycol ether and the derivatives of octyl, isooctyl, nonyl, decyl and dodecyl alcohols, dodecylamine, oleylamine, lauric acid amide, iso-octylamine, lauric and undecylenic acids. Examples describe compositions in the form of capsules, tablets, pills, intravenous injections, suppositories and a cough syrup.