-
1.发明公开VERWENDUNG VON THIAZOL- UND THIADIAZOLVERBINDUNGEN ALS D3 DOPAMINREZEPTORLIGAND 失效使用噻唑和噻二唑D3 DOPAMINREZEPTORLIGAND
公开(公告)号：EP0768879A1
公开(公告)日：1997-04-23
申请号：EP95926897.0
申请日：1995-07-14
Applicant: BASF AKTIENGESELLSCHAFT
Inventor： HELLENDAHL, Beate , LANSKY, Annegret , RENDENBACH-MÜLLER, Beatrice , BACH, Alfred , UNGER, Liliane , TESCHENDORF, Hans-Jürgen , WICKE, Karsten
CPC classification number: C07D285/125 , A61K31/4439 , A61K31/454 , A61K31/496 , C07D277/36 , C07D285/135 , C07D417/12
Abstract: The use is disclosed of thiazole and thiadiazole compounds having the formula (I), in which R1, A, B and Ar have the meanings given in the description. These compounds have a high affinity to the dopamine D¿3? receptor and are therefore useful for treating diseases of the central nervous system.
-
公开(公告)号：EP0771197B1
公开(公告)日：2003-04-09
申请号：EP95926896.2
申请日：1995-07-14
Applicant: BASF AKTIENGESELLSCHAFT
Inventor： HELLENDAHL, Beate , LANSKY, Annegret , RENDENBACH-MÜLLER, Beatrice , BACH, Alfred , UNGER, Liliane , TESCHENDORF, Hans-Jürgen , WICKE, Carsten
IPC: A61K31/33 , A61K31/445 , A61K31/495 , A61P25/18 , A61P25/24
CPC classification number: A61K31/496
-
公开(公告)号：EP0772604A1
公开(公告)日：1997-05-14
申请号：EP95926895.0
申请日：1995-07-14
Applicant: BASF AKTIENGESELLSCHAFT
Inventor： HELLENDAHL, Beate , LANSKY, Annegret , MUNSCHAUER, Rainer , BIALOJAN, Siegfried , UNGER, Liliane , TESCHENDORF, Hans-Jürgen , WICKE, Karsten , DRESCHER, Karla
CPC classification number: C07D403/12 , C07D249/12
Abstract: The present invention relates to triazole compounds of formula (I) in which R1, R2 stand for H or different substituents, A stands for a bivalent group, B stands for a rest of the formula (a), (b) or (c) and Ar stands for optionally substituted phenyl, pyridyl, pyrimidyl or triazinyl. The compounds of the invention have a high affinity for the dopamine-D¿3?-receptor and are therefore usable for the treatment of diseases responding to dopamine-D3-ligands.
-
公开(公告)号：EP0768879B1
公开(公告)日：2003-03-19
申请号：EP95926897.0
申请日：1995-07-14
Applicant: BASF AKTIENGESELLSCHAFT
Inventor： HELLENDAHL, Beate , LANSKY, Annegret , RENDENBACH-MÜLLER, Beatrice , BACH, Alfred , UNGER, Liliane , TESCHENDORF, Hans-Jürgen , WICKE, Karsten
IPC: A61K31/435 , A61K31/44 , A61K31/445
CPC classification number: C07D285/125 , A61K31/4439 , A61K31/454 , A61K31/496 , C07D277/36 , C07D285/135 , C07D417/12
-
Patent Agency Ranking
公开(公告)号：EP0772603B1
公开(公告)日：2002-06-12
申请号：EP95926898.8
申请日：1995-07-14
Applicant: BASF AKTIENGESELLSCHAFT
Inventor： HELLENDAHL, Beate , LANSKY, Annegret , MUNSCHAUER, Rainer , BIALOJAN, Siegfried , UNGER, Liliane , TESCHENDORF, Hans-Jürgen , WICKE, Karsten , DRESCHER, Karla
IPC: C07D239/56 , C07D401/12 , C07D239/38 , C07D239/46 , C07D239/60 , A61K31/505
CPC classification number: C07D239/47 , A61K31/506 , C07D239/38 , C07D239/56 , C07D239/60
-
公开(公告)号：EP0772604B1
公开(公告)日：1999-05-06
申请号：EP95926895.4
申请日：1995-07-14
Applicant: BASF AKTIENGESELLSCHAFT
Inventor： HELLENDAHL, Beate , LANSKY, Annegret , MUNSCHAUER, Rainer , BIALOJAN, Siegfried , UNGER, Liliane , TESCHENDORF, Hans-Jürgen , WICKE, Karsten , DRESCHER, Karla
IPC: C07D249/12 , C07D249/14 , C07D249/08 , C07D401/06 , C07D401/12 , C07D403/12 , C07D401/14 , A61K31/41 , A61K31/505 , A61K31/435 , A61K31/53
CPC classification number: C07D403/12 , C07D249/12
-
公开(公告)号：EP0772603A1
公开(公告)日：1997-05-14
申请号：EP95926898.0
申请日：1995-07-14
Applicant: BASF AKTIENGESELLSCHAFT
Inventor： HELLENDAHL, Beate , LANSKY, Annegret , MUNSCHAUER, Rainer , BIALOJAN, Siegfried , UNGER, Liliane , TESCHENDORF, Hans-Jürgen , WICKE, Karsten , DRESCHER, Karla
CPC classification number: C07D239/47 , A61K31/506 , C07D239/38 , C07D239/56 , C07D239/60
Abstract: The use is disclosed of pyrimidine compounds having the formula (I), in which R?1, R2, R3¿, A, B and Ar have the meanings given in the description. These compounds have a high affinity for the dopamine D¿3? receptor and are therefore useful for treating diseases that respond to dopamine D3 ligands.
-
公开(公告)号：EP0771197A1
公开(公告)日：1997-05-07
申请号：EP95926896.0
申请日：1995-07-14
Applicant: BASF AKTIENGESELLSCHAFT
Inventor： HELLENDAHL, Beate , LANSKY, Annegret , RENDENBACH-MÜLLER, Beatrice , BACH, Alfred , UNGER, Liliane , TESCHENDORF, Hans-Jürgen , WICKE, Carsten
CPC classification number: A61K31/496
Abstract: The present invention relates to the use of heterocyclic compounds of formula (I) Het - A - B - Ar in which Het A, B and Ar have the meanings given in the description. The compounds of the invention have a high affinity for the dopamine-D3-receptor and are therefore usable for the treatment of diseases responding to dopamine-D3-ligands.
-
9.发明公开
公开(公告)号：EP0641324A1
公开(公告)日：1995-03-08
申请号：EP93909981.0
申请日：1993-05-13
Applicant: BASF Aktiengesellschaft
Inventor： HELLENDAHL, Beate , SCHLECKER, Rainer , ROEHL, Franz , ZIPPLIES, Matthias , RASCHACK, Manfred , HAFNER, Matthias
CPC classification number: C07D217/06 , A61K31/47 , C07D217/04
Abstract: Medicament for oral administration which contains as active substance per individual dose, besides the customary galenic auxiliaries, 10 to 1000 mg of a compound of general formula (I) or (II) in which W is a carbonyl group or a single bond, R1 is a hydrogen atom or a group of the general formula R3CO in which R3 is a lower alkyl, lower alkoxy, mono lower alkylamino or di lower alkylamino group, R2 is an alkyl residue with 3 to 20 carbon atoms which may be branched or unbranched and contain 1 to 3 double bonds, a saturated cycle of 3 to 7 carbon atoms integrated into the chain or as substituent, or may be substituted by one or more aromatic rings or contain an oxygen or sulphur atom, as a racemate and as isolated enantiomers; or the addition salt thereof with a physiologically acceptable acid, and the active substances themselves insofar as they are novel.
-
-
-
-
-
-
-
-
Search Results
9
records
(took 0.027 seconds)
