公开(公告)号：WO2009156324A3

公开(公告)日：2012-06-21

申请号：PCT/EP2009057587

申请日：2009-06-18

Applicant: BASF SE ,  WAGNER BARBARA ,  OEHRLEIN REINHOLD ,  HERZOG BERND ,  EICHIN KAI ,  BAISCH GABRIELE ,  PORTMANN STEPHANIE

Inventor： WAGNER BARBARA ,  OEHRLEIN REINHOLD ,  HERZOG BERND ,  EICHIN KAI ,  BAISCH GABRIELE ,  PORTMANN STEPHANIE

IPC: A61Q17/00 ,  A61K8/35 ,  A61Q17/04 ,  C07C49/717 ,  C07C49/747 ,  C07C62/38 ,  C07C69/712 ,  C07C69/757 ,  C07C305/18 ,  C07D311/02 ,  C07F9/40 ,  C07H15/18 ,  C07H15/203 ,  C07H15/26

CPC classification number: A61Q17/04 ,  A61K8/35 ,  A61Q19/08 ,  C07C49/747 ,  C07C62/38 ,  C07C69/712 ,  C07C69/757 ,  C07C305/18 ,  C07C2602/12 ,  C07F9/4006 ,  C07H15/18 ,  C07H15/203 ,  C07H15/26

Abstract: Described is the use of benzotropolone and their derivatives, especially the compounds of formula (1); wherein R2, R3, R4, R5 and R6 independently of one another are hydrogen; OH; C1-C30alkyl, C2-C30al- kenyl, C1-C30alkoxy, C3-C12cycloalkyl or C1C30hydroxyalkyl, which may be substituted by one or more E and/or interrupted by one or more D; C6-C20aryl, which may be substitu¬ ted by one or more G; C4-C20heteroaryl, which may be substituted by one or more G, C2- C18alkenyl, C2-C18alkynyl, C7-C25aralkyl, CN, or -CO-R17; C1-C30mono- or dialkylamino; COR9; COOR9; CONR9R10; CN; SO2R9; OCOOR9; OCOR9; NHCOOR9; NR9COR10; NH2; *-(CO)-NH-(CH2)n1-(PO)-(OR11)2; -(CO)-O-(CH2)n1-(PO)-(OR11)2; sulphate; sulphonate; phosphate; phosphonate; -(CH2)n2-[O-(SO2)]n3-OR11; -O-(CH2)n4(CO)n5-R11; -(O)n6-(CH2)n7-(PO)-(OR9)2; -(O)n6-(CH2)n7-SO2-OR9; halogen; organosilanyl; organo- siloxanyl; or a sugar residue linked directly in an a- or ß-mode via the anomeric oxygen to the benzotropolone system or via a linear or branched alkylene, alkenylene, alkadiene or alkatriene spacer (sugar- (CH2)n-(X1)1 or 0 -benzotropolone system, wherein n = 1 -10 and X1 = -0-; -(CO)-; -0-C0-; -COO-, -NH-; -S-; -SO2-); R1, R7 and R8 independently of one another are hydrogen; C1C12alkyl or C3-C12-cycloalkyl, which may be substituted by one or more E and/or interrupted by one or more D; C6- C20aryl, which may be substituted by one or more G; C4-C20heteroaryl, which may be substituted by one or more G, C2-C18alkenyl, C2-C18alkynyl, C7-C25aralkyl, or COOR9; COR9; CONR9R10; SO3R9; SO2R9; PO3(R9)2; PO2(R9)2; organosilanyl; organosiloxanyl; or a sugar residue linked directly in an a- or ß-mode via the anomeric oxygen to the benzotropolone system or via a linear or branched alkylene, alkenylene, alkadiene or alkatriene spacer (sugar-(CH2)n-(X2)1 or 0-*, wherein n = 1 -10 and X2 = -C(=0)-; -0-C0-*); R9 and R10 independently from each other are hydrogen; C1C18alkyl or C3-C12-cycloalkyl which may be substituted by one or more E and/or interrupted by one or more D; C6- C20aryl, which may be substituted by one or more G; C4-C20heteroaryl, which may be substituted by one or more G; organosilanyl; organosiloxanyl; or a sugar residue linked directly in an a- or ß-mode via the anomeric oxygen or via a linear or branched alkylene, alkenylene, alkadiene or alkatriene spacer (sugar- (CH2)n-*, wherein n = 1 -10); or R9 and R10 together form a five or six membered ring, R11 is hydrogen; or C1-C5alkyl; n1, n2, n4 and n7 independently from each other are a number from 1 to 5; n3, n5 and n6 independently from each other are a 0; or 1; D is -CO-; -COO-; -S-; -SO-; -SO2-; -O-; -NR14-; -S1R19R20-; -POR11-; -CR12=CR13-; or -C=C-; and E is -0R18; -SR18; -NR14R15; -NR14COR15; -C0R17; -COOR16; -CONR14R15; -CN; halogen; Or SO3R18; SO2R18; PO3(R18)2; PO2(R18)2; organosilanyl; organosiloxanyl; or a sugar residue linked directly in an a- or ß-mode via the anomeric oxygen or via a linear or branched alkylene, alkenylene, alkadiene or alkatriene spacer (sugar- (CH2)n-(X1)1 or 0-*, wherein n = 1 -10 and X1 = -0-; -C(=0)-; -0-C0-; -COO-; -NH-; -S-; -SO2-); G is E; C1-C18alkyl, which is optionally interrupted by D; C1-C18perfluoroalkyl; C1-C18alkoxy, which is optionally substituted by E and/or interrupted by D; wherein R12, R13, R14 and R15 independently of each other are hydrogen; C6-C18aryl which is optionally substituted by OH, C1-C18alkyl or C1-C18alkoxy; C1-C18alkyl, which is optionally interrupted by -O-; or Ri4 and Ri5 together form a five or six membered ring, Ri6 is hydrogen; C6-Ci8aryl which is optionally substituted by OH, C1-C18alkyl or d- C18alkoxy; C1-C18alkyl which is optionally interrupted by -O-; R17 is H; C6-C18aryl which is optionally substituted by OH, C1-C18alkyl or C1-C18alkoxy; or d- C18alkyl which is optionally interrupted by -O-; R18 is hydrogen; C6-C18aryl, which is optionally substituted by OH, C1-C18alkyl or d- C18alkoxy; C1-C18alkyl, which is optionally interrupted by -O-; R19 and R20 independently of each other are hydrogen; C1-C18alkyl; C6-C18aryl which is optionally substituted by C1-C18alkyl; and R21 is C1-C18alkyl; or C6-C18aryl, which is substituted by C1-C18alkyl; * means, that this radical is directed to the benzotropolone moiety; for the protection of human and animal hair and skin against UV radiation.

Abstract translation: 描述了苯佐龙醇及其衍生物，特别是式（1）的化合物的用途; 其中R2，R3，R4，R5和R6彼此独立地是氢; 哦; C 1 -C 30烷基，C 2 -C 30亚烯基，C 1 -C 30烷氧基，C 3 -C 12环烷基或C 1 -C 30羟烷基，其可以被一个或多个E取代和/或被一个或多个D中断; 可以被一个或多个G取代的C 6 -C 20芳基; 可以被一个或多个G，C 2 -C 18烯基，C 2 -C 18炔基，C 7 -C 25芳烷基，CN或-CO-R 17取代的C 4 -C 20杂芳基; C 1 -C 30单 - 或二烷基氨基; COR 9; COOR9; CONR9R10; CN; SO 2 R 9; OCOOR9; OCOR9; NHCOOR9; NR9COR10; NH2; * - （CO）-NH-（CH 2）N 1 - （PO） - （OR 11）2; - （CO）-O-（CH 2）N 1 - （PO） - （OR 11）2; 硫酸盐; 磺酸盐; 磷酸盐; 膦酸盐; - （CH 2）N 2 - [O-（SO2）] N3-OR11; -O-（CH2）N4（CO）N5-R11; - （O）N 6 - （CH 2）N 7 - （PO） - （OR 9）2; - （O）N 6 - （CH 2）N7-SO2-OR 9; 卤素; organosilanyl; 有机硅氧烷基 或通过异头氧直接连接到苯佐洛酮系统或通过直链或支链亚烷基，亚烯基，链二烯或烷基三烯间隔物（糖 - （CH 2）n - （X1）1或O - 苯并异噻唑酮系统，其中n = 1-10且X1 = -0-; - （CO） - ; -O-C0-; -COO-，-NH-; -S-; -SO2-）; R 1，R 7和R 8彼此独立地是氢; C 1 -C 12烷基或C 3 -C 12环烷基，其可以被一个或多个E取代和/或被一个或多个D中断; C 6 -C 20芳基，其可以被一个或多个G取代; 可以被一个或多个G，C 2 -C 18烯基，C 2 -C 18炔基，C 7 -C 25芳烷基或COOR 9取代的C 1 -C 20杂芳基; COR 9; CONR9R10; SO3R9; SO 2 R 9; PO3（R 9）2; PO2（R 9）2; organosilanyl; 有机硅氧烷; 或直链或α-支链的亚烷基，链烯二烯或三亚胺间隔基（糖 - （CH 2）n - （X 2）1或O - *，其中n = 1-10，X2 = -C（= O） - ; - O-C0- *）; R9和R10彼此独立地是氢; 可以被一个或多个E取代和/或被一个或多个D中断的C 1 -C 18烷基或C 3 -C 12 - 环烷基; 可以被一个或多个G取代的C 6 -C 20芳基; 可以被一个或多个G取代的C 4 -C 20杂芳基; organosilanyl; 有机硅氧烷; 或通过端基异构体氧或经由直链或支链的亚烷基，亚烯基，链二烯或烷基三烯间隔物（糖 - （CH 2）n - ），其中n = 1-10）直接连接在α-或β-模式中的糖残基; 或R 9和R 10一起形成五元或六元环，R 11为氢; 或C 1 -C 5烷基; n1，n2，n4和n7彼此独立地为1至5的数; n3，n5和n6彼此独立地为0; 或1; D是-CO-; -COO-; -S-; -所以-; -SO2-; -O-; NR 14; -S1R19R20-; -POR11-; -CR12 = CR13-; 或-C = C-; E为-0R18; -SR18; -NR14R15; -NR14COR15; -C0R17; -COOR16; -CONR14R15; -CN; 卤素; 或SO3R18; SO2R18; PO3（R18）2; PO2（R18）2; organosilanyl; 有机硅氧烷; 或通过异头氧直接或通过直链或支链亚烷基，亚烯基，链二烯或烷三胺间隔基（糖 - （CH 2）n - （X1）1或0- *）直接连接在α-或β-模式上的糖残基，其中 n = 1-10且X1 = -0-; -C（= O） - ; - O-O-COO-; -NH-; -S-; -SO2-）; G是E 任选地被D中断的C 1 -C 18烷基; C1-C18perfluoroalkyl; C1-C18烷氧基，其任选地被E取代和/或被D中断; 其中R 12，R 13，R 14和R 15彼此独立地是氢; 任选被OH，C 1 -C 18烷基或C 1 -C 18烷氧基取代的C 6 -C 18芳基; 任选地被-O-间隔的C 1 -C 18烷基; 或R 14和R 15一起形成五元或六元环，R 6为氢; 任选被OH，C 1 -C 18烷基或C 1 -C 18烷氧基取代的C 6 -C 18芳基; 任选被-O-间隔的C 1 -C 18烷基; R17为H; 任选被OH，C 1 -C 18烷基或C 1 -C 18烷氧基取代的C 6 -C 18芳基; 或任选被-O-中断的C 1 -C 18烷基; R18是氢; 任选被OH，C 1 -C 18烷基或C 1 -C 18烷氧基取代的C 6 -C 18芳基; 任选地被-O-间隔的C 1 -C 18烷基; R 19和R 20彼此独立地是氢; C1-C18烷基; 任选被C 1 -C 18烷基取代的C 6 -C 18芳基; 和R 21是C 1 -C 18烷基; 或被C 1 -C 18烷基取代的C 6 -C 18芳基; *表示该基团针对苯佐洛尔酮部分; 用于保护人和动物的头发和皮肤免受紫外线辐射。

公开(公告)号：WO2014170833A3

公开(公告)日：2015-01-29

申请号：PCT/IB2014060751

申请日：2014-04-16

Applicant: BASF SE ,  BASF CHINA CO LTD

Inventor： ÖHRLEIN REINHOLD ,  BAISCH GABRIELE

IPC: C08G77/04 ,  C07F7/02 ,  G02F1/167

CPC classification number: C07F7/21 ,  C07F7/084 ,  C09B69/008 ,  G02F1/167 ,  G02F2001/1678

Abstract: The present invention provides salts of a cation and an anion, wherein the cation comprises (i) a silsesquioxane moiety of formula (1) (ii) a chromophoric moiety D, which may which may be substituted with one or more substituents selected from the group consisting of C1-10-alkyl, phenyl, halogen, OC1-6-alkyl, OH, NH2 and NO2, and (iii) a moiety of formula (2) wherein L4 is C1-20-alkylene, phenylene-C1-20-alkylene or C1-20-alkylene-phenylene-C1-20-alkylene, R11, R12, R13 and R14 are independently from each other hydrogen or C1-4-alkyl, R15, R16, R17 and R18 are independently from each other C1-4-alkyl, R19 is C1-20-alkyl, which may be substituted with phenyl, O-C1-6-alkyl or NO2, and d is an integer from 1 to 25, and electrophoretic devices comprising the salts.

Abstract translation: 本发明提供阳离子和阴离子的盐，其中阳离子包括（i）式（1）的倍半硅氧烷部分（ii）发色部分D，其可以被一个或多个选自以下基团的取代基取代： 由C 1-10 - 烷基，苯基，卤素，OC 1-6 - 烷基，OH，NH 2和NO 2组成，和（iii）式（2）的部分，其中L 4是C 1-20亚烷基，亚苯基-C1-20- 亚烷基或C 1-20亚烷基 - 亚苯基-C1-20-亚烷基，R11，R12，R13和R14彼此独立地为氢或C1-4 - 烷基，R15，R16，R17和R18彼此独立地为C1- 4-烷基，R 19为可被苯基，O-C 1-6 - 烷基或NO 2取代的C 1-20烷基，d为1至25的整数，以及包含该盐的电泳装置。

公开(公告)号：ES2340260T3

公开(公告)日：2010-06-01

申请号：ES02764615

申请日：2002-07-02

Applicant: BASF SE

Inventor： OHRLEIN REINHOLD ,  BAISCH GABRIELE ,  KIRNER HANS JORG ,  BIENEWALD FRANK ,  BURKHARDT STEPHAN ,  STUDER MARTIN

IPC: C07C67/307 ,  C07C227/32 ,  C07B53/00 ,  C07B61/00 ,  C07C67/30 ,  C07C67/31 ,  C07C69/67 ,  C07C69/675 ,  C07C69/708 ,  C07C69/716 ,  C07C69/732 ,  C07C69/738 ,  C07C227/06 ,  C07C227/16 ,  C07C229/22 ,  C07C231/02 ,  C07C235/04 ,  C07C235/06 ,  C07C235/74 ,  C07C247/12 ,  C07D207/34 ,  C12P7/62

Abstract: Un proceso para la preparación del intermedio de la fórmula VI **(Ver fórmula)** en donde Ra'' y Rc'' son cada uno independientemente hidrógeno o un grupo protector hidroxi o juntos son un grupo protector hidroxi puenteado, y Rb es un grupo protector carboxi, cuyo proceso comprende la conversión de un compuesto de la fórmula I **(Ver fórmula)** en donde X es halógeno; un radical de ácido carboxílico o sulfónico orgánico que tiene de 1 a 24 átomos de carbono, no sustituido o sustituido por 1 a 3 radicales, deleccionados de alcoxi con hasta siete átomos de carbono, halógeno, nitro, alcoxicarbonilo con hasta siete átomos de carbono, fenilo, fenil-alquilo C1-7, feniloxi, alcanoiloxi con hasta siete átomos de carbono, benzoiloxi, di-alquilo C1-7-amino, N-fenil-alquilo C1-7-N-C alquilo C1-7-amino, N,N-di(fenil-alquilo C1-7)-amino, carbamoilo, tiocarbamoilo, sulfamoilo y ciano; hidrocarbiloxi activado o hidrocarbiltio activado seleccionado de alquiloxi con hasta siete átomos de carbono, sustituido o no sustituido en la posición 1 mediante carbonilo esterificado, ciano o mediante fenilcarbonilo; ariloxi que tiene de 6 a 12 átomos en el anillo; heterocicliloxi que tiene de 4 a 12 átomos en el anillo y hasta tres heteroátomos seleccionados de nitrógeno, azufre y oxígeno; o -N(CH3)-OCH3, Ra es hidrógeno o un grupo protector hidroxi y Rb es un grupo protector carboxi, en un compuesto de la fórmula I* **(Ver fórmula)** en donde Rc'' es hidrógeno o un grupo protector hidroxilo, Rb'' es hidrógeno o un grupo protector carboxi y R* y R** son cada uno independientemente hidrógeno o un grupo protector amida, la conversión del compuesto de la fórmula I* en un compuesto de la fórmula XVI **(Ver fórmula)** en donde Ra'' y Rc'' son cada uno independientemente hidrógeno o un grupo protector hidroxi, R* y R** son cada uno independientemente hidrógeno o un grupo protector amida, y Rb es un grupo protector carboxi; la reducción del intermedio de la fórmula XVI, y la remoción del grupo protector R* y R**, si está presente, para proporcionar el intermedio de la fórmula VI; en donde la conversión de compuesto de la fórmula I* en el compuesto de la fórmula XVI comprende hacer reaccionar el compuesto de la fórmula I*, en donde Rc'' es hidrógeno y Rb'', R* y R** son como se define aquí, con un compuesto de la fórmula XX en la presencia de una base fuerte **(Ver fórmula)** en donde Rb es un grupo protector carboxi, para formar un compuesto de la fórmula XV **(Ver fórmula)** en donde R* y R** son como se definió anteriormente para los compuestos de la fórmula I*, Rc'' es hidrógeno y Rb es un grupo protector carboxi; el compuesto (XV) luego se reduce diastereoselectivamente para formar un sin-diol de la fórmula XVI **(Ver fórmula)** en donde Ra'' y Rc'' son hidrógeno; o, después, de introducción posterior de grupos protectores, Ra'' y Rc'' son cada uno independientemente hidrógeno o un grupo protector hidroxi, con la condición que por lo menos uno de los radicales es tal un grupo protector, o Ra'' y Rc'' juntos son un grupo protector hidroxi puenteado; R* y R** son como se define para el compuesto de la fórmula I*, y Rb es un grupo protector carboxi.

公开(公告)号：DK1404642T3

公开(公告)日：2010-05-17

申请号：DK02764615

申请日：2002-07-02

Applicant: BASF SE

Inventor： OEHRLEIN REINHOLD ,  BAISCH GABRIELE ,  KIRNER HANS JOERG ,  BIENEWALD FRANK ,  BURKHARDT STEPHAN ,  STUDER MARTIN

IPC: C07C67/307 ,  C07C227/32 ,  C07B53/00 ,  C07B61/00 ,  C07C67/31 ,  C07C69/67 ,  C07C69/675 ,  C07C69/708 ,  C07C69/716 ,  C07C69/732 ,  C07C69/738 ,  C07C227/06 ,  C07C227/16 ,  C07C229/22 ,  C07C231/02 ,  C07C235/04 ,  C07C235/06 ,  C07C235/74 ,  C07C247/12 ,  C07D207/34 ,  C12P7/62

公开(公告)号：DE60235365D1

公开(公告)日：2010-04-01

申请号：DE60235365

申请日：2002-07-02

Applicant: BASF SE

Inventor： OEHRLEIN REINHOLD ,  BAISCH GABRIELE ,  KIRNER HANS JOERG ,  BIENEWALD FRANK ,  BURKHARDT STEPHAN ,  STUDER MARTIN

IPC: C07C67/307 ,  C07C227/32 ,  C07B53/00 ,  C07B61/00 ,  C07C67/31 ,  C07C69/67 ,  C07C69/675 ,  C07C69/708 ,  C07C69/716 ,  C07C69/732 ,  C07C69/738 ,  C07C227/06 ,  C07C227/16 ,  C07C229/22 ,  C07C231/02 ,  C07C235/04 ,  C07C235/06 ,  C07C235/74 ,  C07C247/12 ,  C07D207/34 ,  C12P7/62

公开(公告)号：AT513861T

公开(公告)日：2011-07-15

申请号：AT06763916

申请日：2006-06-28

Applicant: BASF SE

Inventor： CRACIUN LILIANA ,  POLISHCHUK OREST ,  SCHRIVER GEORGE WILLIAM ,  BAISCH GABRIELE ,  OEHRLEIN REINHOLD

IPC: C08F30/02 ,  C07F9/38 ,  C07F9/40 ,  C09D143/02 ,  C09J143/02

Abstract: The present invention relates to polymerizable N-substituted acrylamide phosphorus-containing monomers, organic polymers formed from the same. Incorporation of said monomers into adhesives, pigment dispersants, coatings or films for polar surfaces or particles gives improved adhesive, anti-corrosive, and flame retardant properties.

公开(公告)号：AT527304T

公开(公告)日：2011-10-15

申请号：AT04735241

申请日：2004-05-28

Applicant: BASF SE

Inventor： ROGERS JONATHAN ,  BAUDIN GISELE ,  JUNG TUNJA ,  OEHRLEIN REINHOLD ,  BAISCH GABRIELE

IPC: C08G77/38 ,  C08F2/50 ,  G03F7/00 ,  G03F7/029 ,  G03F7/075

Abstract: Polymeric photoinitiators of the formula I or II wherein n and m independently of one another are 3-5; o is 10-16; p is 4-8; R is phenyl-CO-CO-O-; Y and Y' independently of one another are C 1 -C 10 alkylene or -[(CH 2 ) a -O-(CH 2 ) b ] c - wherein a is 2-10, b is 0-10, c is 1-3; with the proviso that they are, however, at least 1 if the methylene group in question is between two oxygen atoms.

公开(公告)号：DE60334444D1

公开(公告)日：2010-11-18

申请号：DE60334444

申请日：2003-02-25

Applicant: BASF SE

Inventor： OEHRLEIN REINHOLD ,  SCHOENING KAI-UWE ,  BAISCH GABRIELE ,  SCHMIDT JEMIMA ,  BAUDIN GISELE ,  JUNG TUNJA

IPC: C12N11/08 ,  C12P9/00 ,  C07F7/08 ,  C07F7/10

公开(公告)号：EP2986658A4

公开(公告)日：2017-03-08

申请号：EP14785766

申请日：2014-04-16

Applicant: BASF SE

Inventor： ÖHRLEIN REINHOLD ,  BAISCH GABRIELE

IPC: C09B69/00 ,  G02F1/167

CPC classification number: C07F7/21 ,  C07F7/084 ,  C09B69/008 ,  G02F1/167 ,  G02F2001/1678

Abstract: The present invention provides salts of a cation and an anion, wherein the cation comprises (i) a silsesquioxane moiety of formula (ii) a chromophoric moiety D, which may which may be substituted with one or more substituents selected from the group consisting of C1-10-alkyl, phenyl, halogen, OC1-6-alkyl, OH, NH2 and NO2, and (iii) a moiety of formula wherein L4 is C1-20-alkylene, phenylene-C1-20-alkylene or C1-20-alkylene-phenylene-C1-20alkylene, R11, R12, R13 and R14 are independently from each other hydrogen or C1-4-alkyl, R15, R16, R17 and R18 are independently from each other C1-4-alkyl, R19 is C1-20-alkyl, which may be substituted with phenyl, O—C1-6-alkyl or NO2, and d is an integer from 1 to 25, and electrophoretic devices comprising the salts.

公开(公告)号：EP2834288A4

公开(公告)日：2015-12-30

申请号：EP13773124

申请日：2013-04-02

Applicant: BASF SE

Inventor： ÖHRLEIN REINHOLD ,  BAISCH GABRIELE

IPC: C09B69/00 ,  G02F1/167

CPC classification number: C08G77/045 ,  C07F7/21 ,  C08G77/388 ,  C08G77/392 ,  C09B69/008 ,  G09G3/344

Abstract: The present invention provides compounds of Formula (1A), wherein Formula (II) is Formula (III) and Formula (1B) wherein Formula (IV) is Formula (V) and electrophoretic devices comprising the compounds of formula (1A) or (1B).

Abstract translation: 本发明提供式（1A）化合物，其中式（II）为式（III）和式（1B），其中式（Ⅳ）为式（Ⅴ）和包含式（1A）或（1B）化合物的电泳装置 ）。