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1.发明申请
公开(公告)号：WO2016050816A3
公开(公告)日：2016-06-02
申请号：PCT/EP2015072506
申请日：2015-09-30
Applicant: BASF SE
Inventor： BUDDE MICHAEL , BRAUN MICHAEL , DAEUWEL JUERGEN , OEDMAN PETER , BALDENIUS KAI-UWE , KLEINER MATTHIAS , FREYER STEPHAN
IPC: C12P13/02
CPC classification number: C12P13/02 , C12N9/78 , C12N9/80 , C12Y305/01004 , C12Y305/05001
Abstract: The present invention relates to means and methods for producing an amide compound from a nitrile compound with less acrylic acid as by-product using a Nitrile hydratase (NHase) and Amidase producing microorganism as biocatalyst. Also provided is an aqueous amide compound obtained by the methods of the invention as well as a composition comprising acrylamide or polyacrylamide as well as a dried microorganism exhibiting a NHase/Amidase activity ratio of at least 400 when being brought into contact with a nitrile compound to convert said nitrile compound into an amide compound.
Abstract translation: 本发明涉及使用腈水合酶（NHase）和产酰胺酶微生物作为生物催化剂由腈化合物和少量丙烯酸副产物生产酰胺化合物的方法和方法。 还提供了通过本发明的方法获得的含水酰胺化合物以及包含丙烯酰胺或聚丙烯酰胺的组合物以及当与腈化合物接触时显示至少400的NHase /酰胺酶活性比的干燥微生物与 将所述腈化合物转化成酰胺化合物。
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公开(公告)号：AU2015326905A1
公开(公告)日：2017-04-06
申请号：AU2015326905
申请日：2015-09-30
Applicant: BASF SE
Inventor： BUDDE MICHAEL , BRAUN MICHAEL , DAEUWEL JUERGEN , OEDMAN PETER , BALDENIUS KAI-UWE , KLEINER MATTHIAS , FREYER STEPHAN
IPC: C12P13/02
Abstract: The present invention relates to means and methods for producing an amide compound from a nitrile compound with less acrylic acid as by-product using a Nitrile hydratase (NHase) and Amidase producing microorganism as biocatalyst. Also provided is an aqueous amide compound obtained by the methods of the invention as well as a composition comprising acrylamide or polyacrylamide as well as a dried microorganism exhibiting a NHase/Amidase activity ratio of at least 400 when being brought into contact with a nitrile compound to convert said nitrile compound into an amide compound.
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3.发明专利
公开(公告)号：CA2962510A1
公开(公告)日：2016-04-07
申请号：CA2962510
申请日：2015-09-30
Applicant: BASF SE
Inventor： BRAUN MICHAEL , DAEUWEL JUERGEN , LANG HANS-JUERGEN , OEDMAN PETER , BALDENIUS KAI-UWE , KLEINER MATTHIAS , KIEFER MICHAEL , FREYER STEPHAN , BUDDE MICHAEL
Abstract: The present invention relates to methods for preparing an aqueous acrylamide solution having a low acrylic acid concentration. In addition, the present invention relates to methods for reducing the acrylic acid concentration of an aqueous acrylamide solution. The methods involve a bioconversion of acrylonitrile to acrylamide in the presence of a biocatalyst, wherein during the bioconversion the content of acrylonitrile is maintained at 0.3 w/w % or more referred to the total weight of the composition in the reactor. Also provided is an aqueous acrylamide solution which is obtained by the methods of the present invention. Furthermore, the present invention is related to an acrylamide homopolymer or copolymer obtained by polymerizing the acrylamide of the aqueous solution.
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公开(公告)号：CO2017004034A2
公开(公告)日：2017-09-20
申请号：CO2017004034
申请日：2017-04-26
Applicant: BASF SE
Inventor： BRAUN MICHAEL , DAEUWEL JUERGEN , OEDMAN PETER , BALDENIUS KAI-UWE , KLEINER MATTHIAS , FREYER STEPHAN , BUDDE MICHAEL
IPC: C12P13/02
Abstract: La presente invención se refiere a medios y métodos para producir un compuesto de amida a partir de un compuesto de nitrilo con menor cantidad de ácido acrílico como subproducto usando un microorganismo que produce nitrilo hidratasa (NHasa) y amidasa como biocatalizador. También se proporciona un compuesto acuoso de amida obtenido mediante los métodos de la invención, así como también una composición que comprende acrilamida o poliacrilamida, así como también un microorganismo seco que exhibe una relación de actividad de NHasa/amidasa de al menos 400 cuando entra en contacto con un compuesto de nitrilo para convertir el compuesto de nitrilo en un compuesto de amida.
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Patent Agency Ranking5.发明专利
公开(公告)号：AU2015326907B2
公开(公告)日：2019-07-04
申请号：AU2015326907
申请日：2015-09-30
Applicant: BASF SE
Inventor： LANG HANS-JUERGEN , OEDMAN PETER , BALDENIUS KAI-UWE , KLEINER MATTHIAS , KIEFER MICHAEL , FREYER STEPHAN , BUDDE MICHAEL , BRAUN MICHAEL , DAEUWEL JUERGEN
IPC: C12P13/02
Abstract: The present invention relates to methods for preparing an aqueous acrylamide solution having a low acrylic acid concentration. In addition, the present invention relates to methods for reducing the acrylic acid concentration of an aqueous acrylamide solution. The methods involve a bioconversion of acrylonitrile to acrylamide in the presence of a biocatalyst, wherein during the bioconversion the content of acrylonitrile is maintained at 0.3 w/w % or more referred to the total weight of the composition in the reactor. Also provided is an aqueous acrylamide solution which is obtained by the methods of the present invention. Furthermore, the present invention is related to an acrylamide homopolymer or copolymer obtained by polymerizing the acrylamide of the aqueous solution.
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公开(公告)号：CA2962325A1
公开(公告)日：2016-04-07
申请号：CA2962325
申请日：2015-09-30
Applicant: BASF SE
Inventor： BUDDE MICHAEL , BRAUN MICHAEL , DAEUWEL JUERGEN , OEDMAN PETER , BALDENIUS KAI-UWE , KLEINER MATTHIAS , FREYER STEPHAN
IPC: C12P13/02
Abstract: The present invention relates to means and methods for producing an amide compound from a nitrile compound with less acrylic acid as by-product using a Nitrile hydratase (NHase) and Amidase producing microorganism as biocatalyst. Also provided is an aqueous amide compound obtained by the methods of the invention as well as a composition comprising acrylamide or polyacrylamide as well as a dried microorganism exhibiting a NHase/Amidase activity ratio of at least 400 when being brought into contact with a nitrile compound to convert said nitrile compound into an amide compound.
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公开(公告)号：CO2017004030A2
公开(公告)日：2017-09-20
申请号：CO2017004030
申请日：2017-04-26
Applicant: BASF SE
Inventor： BRAUN MICHAEL , DAEUWEL JUERGEN , LANG HANS-JUERGEN , OEDMAN PETER , BALDENIUS KAI-UWE , KLEINER MATTHIAS , KIEFER MICHAEL , FREYER STEPHAN , BUDDE MICHAEL
IPC: C12P13/02
Abstract: La presente invención se refiere a métodos para preparar una solución acuosa de acrilamida que tiene una baja concentración de ácido acrílico. Asimismo, la presente invención se refiere a métodos para reducir la concentración de ácido acrílico de una solución acuosa de acrilamida. Los métodos incluyen una bioconversión de acrilonitrilo en acrilamida en presencia de un biocatalizador, en donde, durante la bioconversión, el contenido de acrilonitrilo se mantiene a 0,3 % p/p o más con respecto al peso total de la composición en el reactor. También se proporciona una solución acuosa de acrilamida que se obtiene mediante los métodos de la presente invención. Además, la presente invención se refiere a un homopolímero o copolímero de acrilamida que se obtiene mediante polimerización de la acrilamida de la solución acuosa.
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公开(公告)号：AU2015326905B2
公开(公告)日：2019-07-04
申请号：AU2015326905
申请日：2015-09-30
Applicant: BASF SE
Inventor： BUDDE MICHAEL , BRAUN MICHAEL , DAEUWEL JUERGEN , OEDMAN PETER , BALDENIUS KAI-UWE , KLEINER MATTHIAS , FREYER STEPHAN
IPC: C12P13/02
Abstract: The present invention relates to means and methods for producing an amide compound from a nitrile compound with less acrylic acid as by-product using a Nitrile hydratase (NHase) and Amidase producing microorganism as biocatalyst. Also provided is an aqueous amide compound obtained by the methods of the invention as well as a composition comprising acrylamide or polyacrylamide as well as a dried microorganism exhibiting a NHase/Amidase activity ratio of at least 400 when being brought into contact with a nitrile compound to convert said nitrile compound into an amide compound.
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9.发明专利
公开(公告)号：AU2015326907A1
公开(公告)日：2017-04-06
申请号：AU2015326907
申请日：2015-09-30
Applicant: BASF SE
Inventor： BRAUN MICHAEL , DAEUWEL JUERGEN , LANG HANS-JUERGEN , OEDMAN PETER , BALDENIUS KAI-UWE , KLEINER MATTHIAS , KIEFER MICHAEL , FREYER STEPHAN , BUDDE MICHAEL
IPC: C12P13/02
Abstract: The present invention relates to methods for preparing an aqueous acrylamide solution having a low acrylic acid concentration. In addition, the present invention relates to methods for reducing the acrylic acid concentration of an aqueous acrylamide solution. The methods involve a bioconversion of acrylonitrile to acrylamide in the presence of a biocatalyst, wherein during the bioconversion the content of acrylonitrile is maintained at 0.3 w/w % or more referred to the total weight of the composition in the reactor. Also provided is an aqueous acrylamide solution which is obtained by the methods of the present invention. Furthermore, the present invention is related to an acrylamide homopolymer or copolymer obtained by polymerizing the acrylamide of the aqueous solution.
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