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1.发明申请
公开(公告)号：WO2016050816A3
公开(公告)日：2016-06-02
申请号：PCT/EP2015072506
申请日：2015-09-30
Applicant: BASF SE
Inventor： BUDDE MICHAEL , BRAUN MICHAEL , DAEUWEL JUERGEN , OEDMAN PETER , BALDENIUS KAI-UWE , KLEINER MATTHIAS , FREYER STEPHAN
IPC: C12P13/02
CPC classification number: C12P13/02 , C12N9/78 , C12N9/80 , C12Y305/01004 , C12Y305/05001
Abstract: The present invention relates to means and methods for producing an amide compound from a nitrile compound with less acrylic acid as by-product using a Nitrile hydratase (NHase) and Amidase producing microorganism as biocatalyst. Also provided is an aqueous amide compound obtained by the methods of the invention as well as a composition comprising acrylamide or polyacrylamide as well as a dried microorganism exhibiting a NHase/Amidase activity ratio of at least 400 when being brought into contact with a nitrile compound to convert said nitrile compound into an amide compound.
Abstract translation: 本发明涉及使用腈水合酶（NHase）和产酰胺酶微生物作为生物催化剂由腈化合物和少量丙烯酸副产物生产酰胺化合物的方法和方法。 还提供了通过本发明的方法获得的含水酰胺化合物以及包含丙烯酰胺或聚丙烯酰胺的组合物以及当与腈化合物接触时显示至少400的NHase /酰胺酶活性比的干燥微生物与 将所述腈化合物转化成酰胺化合物。
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公开(公告)号：WO2014041011A3
公开(公告)日：2014-05-08
申请号：PCT/EP2013068786
申请日：2013-09-11
Applicant: BASF SE , BASF SCHWEIZ AG , UNIV GRONINGEN
Inventor： BALDENIUS KAI-UWE , DITRICH KLAUS , BREUER MICHAEL , NAVICKAS VAIDOTAS , DICK JANSEN , BARTSCH SEBASTIAN , CRISMARU CIPRIAN GICA
CPC classification number: C12N9/1096 , C12N9/0006 , C12P13/001 , C12Y101/01001 , C12Y104/01001 , C12Y206/01018
Abstract: The present invention relates to a novel enzymatically catalyzed method for the production of aliphatic primary amines, which method comprises the enzymatic oxidation of a primary aliphatic alcohol catalyzed by an alcohol dehydrogenase, amination of the resulting oxocompound catalyzed by a transaminase and optionally coupled with an enzymatically catalyzed regeneration of the consumed cofactor; recombinant expression systems and microorganisms procuring the required enzyme activities; and bioreactors for performing such methods; as well as the use of the obtained amines in organic synthesis, in particular for preparing organic polymers.
Abstract translation: 本发明涉及用于生产脂族伯胺的新的酶催化方法，该方法包括由醇脱氢酶催化的伯脂肪醇的酶氧化，由转氨酶催化的所得氧化合物的胺化，并任选地与酶 消耗的辅因子的催化再生; 重组表达系统和微生物获得所需的酶活性; 和用于进行这种方法的生物反应器; 以及在有机合成中使用得到的胺，特别是制备有机聚合物。
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公开(公告)号：BR112015004662B1
公开(公告)日：2022-02-15
申请号：BR112015004662
申请日：2013-09-03
Applicant: BASF SE
Inventor： KINDLER ALOIS , REHFINGER ALWIN , PIATESI ANDREA , BALDENIUS KAI-UWE , DITRICH KLAUS , ZAJACZKOWSKI-FISCHER MARTA , BÖHLING RALF
IPC: C07C55/20 , C07C59/147 , C12P7/64
Abstract: processo para preparar ácido sebácico. processo de preparação de ácido sebácico por meio de reação, em uma primeira etapa (i), de ácido linoleico com água catalisada por uma hidratase de oleato para formar ácido 10-hidróxi-12-octadecenoico, em uma segunda etapa (ii) pirólise do ácido 10-hidróxi-12-octadecenóico em 1-octeno e ácido 10-oxodecanoico e, em terceira etapa (iii), oxidação do ácido 10- oxodecanoico em ácido sebácico.
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公开(公告)号：AU2015326905A1
公开(公告)日：2017-04-06
申请号：AU2015326905
申请日：2015-09-30
Applicant: BASF SE
Inventor： BUDDE MICHAEL , BRAUN MICHAEL , DAEUWEL JUERGEN , OEDMAN PETER , BALDENIUS KAI-UWE , KLEINER MATTHIAS , FREYER STEPHAN
IPC: C12P13/02
Abstract: The present invention relates to means and methods for producing an amide compound from a nitrile compound with less acrylic acid as by-product using a Nitrile hydratase (NHase) and Amidase producing microorganism as biocatalyst. Also provided is an aqueous amide compound obtained by the methods of the invention as well as a composition comprising acrylamide or polyacrylamide as well as a dried microorganism exhibiting a NHase/Amidase activity ratio of at least 400 when being brought into contact with a nitrile compound to convert said nitrile compound into an amide compound.
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5.发明专利
公开(公告)号：CA2962510A1
公开(公告)日：2016-04-07
申请号：CA2962510
申请日：2015-09-30
Applicant: BASF SE
Inventor： BRAUN MICHAEL , DAEUWEL JUERGEN , LANG HANS-JUERGEN , OEDMAN PETER , BALDENIUS KAI-UWE , KLEINER MATTHIAS , KIEFER MICHAEL , FREYER STEPHAN , BUDDE MICHAEL
Abstract: The present invention relates to methods for preparing an aqueous acrylamide solution having a low acrylic acid concentration. In addition, the present invention relates to methods for reducing the acrylic acid concentration of an aqueous acrylamide solution. The methods involve a bioconversion of acrylonitrile to acrylamide in the presence of a biocatalyst, wherein during the bioconversion the content of acrylonitrile is maintained at 0.3 w/w % or more referred to the total weight of the composition in the reactor. Also provided is an aqueous acrylamide solution which is obtained by the methods of the present invention. Furthermore, the present invention is related to an acrylamide homopolymer or copolymer obtained by polymerizing the acrylamide of the aqueous solution.
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Patent Agency Ranking
公开(公告)号：ES2370515T3
公开(公告)日：2011-12-19
申请号：ES06743390
申请日：2006-05-02
Applicant: BASF SE
Inventor： OFTRING ALFRED , BRAUN GEROLD , WIRSING FRIEDRICH , STAMM ARMIN , BALDENIUS KAI-UWE
IPC: C07C227/26 , C07C229/16
Abstract: Procedimiento para la preparación de sal de tri(metal alcalino) del ácido metilglicino-N,N-diacético de color claro, con bajo contenido en subproductos mediante la hidrólisis alcalina de metilglicinonitrildiacetonitrilo (MGDN) con las etapas en la secuencia (a) a (f): (a) mezclar MGDN con álcali acuoso a una temperatura
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公开(公告)号：CA2756514C
公开(公告)日：2020-03-24
申请号：CA2756514
申请日：2010-03-31
Applicant: BASF SE
Inventor： PIATESI ANDREA , HABICHER TILO , BUESCHEL MICHAEL , WANG LI-WEN , REICHERT JUERGEN , PACKE-WIRTH RAINER , BALDENIUS KAI-UWE , KROMM ERICH , HAEFNER STEFAN , SCHWALB CARSTEN , HOEFFKEN HANS WOLFGANG
Abstract: The invention relates to the use of an enzyme preparation which catalyzes the degradation of formaldehyde for reducing the formaldehyde content in a formaldehyde-containing formulation. In a preferred embodiment, the enzyme preparation contains a formaldehyde dismutase from a Pseudomonas putida strain. Further, the invention refers to a process for reducing the formal dehyde content in cross-linking agents for textile finishing or in polymer dispersions used, e.g. in construction chemistry. Further the invention relates to the use of an enzyme preparation which catalyzes the degradation of aldehydes for reducing the formaldehyde content in an aldehyde-containing formulation. Furthermore, the invention relates to a novel variant of the formaldehyde dismutase from Pseudomonas putida.
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公开(公告)号：AU2015314601B2
公开(公告)日：2019-07-04
申请号：AU2015314601
申请日：2015-06-30
Applicant: BASF SE
Inventor： NAVICKAS VAIDOTAS , BALDENIUS KAI-UWE , BREUER MICHAEL , WILDBERGER PATRICIA , PFEIFFER MARTIN , NIDETZKY BERND
Abstract: The present invention relates to methods of producing sugar phosphates by enzymatic transphosphorylation, wherein the phosphoryl transfer from phosphate donor substrates to sugar substrates is catalyzed by an enzyme having alpha-glucose-1-phophatase activity. Furthermore, the present invention relates to a biocatalyst having sucrose phosphorylase as well as alpha-glucose-1-phosphatase activity and its use. The production of an enzyme having alpha-glucose-1-phophatase activity and its use in the transphosphorylation of sugar substrates is also presented herein.
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公开(公告)号：CO2017004030A2
公开(公告)日：2017-09-20
申请号：CO2017004030
申请日：2017-04-26
Applicant: BASF SE
Inventor： BRAUN MICHAEL , DAEUWEL JUERGEN , LANG HANS-JUERGEN , OEDMAN PETER , BALDENIUS KAI-UWE , KLEINER MATTHIAS , KIEFER MICHAEL , FREYER STEPHAN , BUDDE MICHAEL
IPC: C12P13/02
Abstract: La presente invención se refiere a métodos para preparar una solución acuosa de acrilamida que tiene una baja concentración de ácido acrílico. Asimismo, la presente invención se refiere a métodos para reducir la concentración de ácido acrílico de una solución acuosa de acrilamida. Los métodos incluyen una bioconversión de acrilonitrilo en acrilamida en presencia de un biocatalizador, en donde, durante la bioconversión, el contenido de acrilonitrilo se mantiene a 0,3 % p/p o más con respecto al peso total de la composición en el reactor. También se proporciona una solución acuosa de acrilamida que se obtiene mediante los métodos de la presente invención. Además, la presente invención se refiere a un homopolímero o copolímero de acrilamida que se obtiene mediante polimerización de la acrilamida de la solución acuosa.
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公开(公告)号：MX2014010905A
公开(公告)日：2014-10-15
申请号：MX2014010905
申请日：2013-03-11
Applicant: BASF SE
Inventor： PIATESI ANDREA , SIEGEL WOLFGANG , BALDENIUS KAI-UWE
IPC: C12P13/00
Abstract: La presente invención se refiere a métodos de un nuevo tipo para producir biocatalíticamente nitrilos a partir de oximas usando oxima deshidratasas y a mutaciones de un nuevo tipo que tiene actividad de oxima deshidratasa y uso de los mismos en un método para producir biocatalíticamente nitrilos, tales como en particular para producir citral nitirlo, neral nitrilo, geranial nitrilo, o citronelilnitirlo a partir de ciral oxima, neral oxima, geranial oxima, o citronelal oxima, y a oxima deshidratasas que pueden usarse para los mismos, secuencias de nucleótidos para lo mismo y construcciones de expresión de microorganismos que comprenden secuencias de nucleótidos.
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