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1.发明申请METHOD FOR PURIFICATION OF ANTIBODIES, ANTIBODY FRAGMENTS OR ENGINEERED VARIANTS THEREOF USING SPECIFIC ANTHRAQUINONE DYE-LIGAND STRUCTURES 审中-公开使用特定的蒽醌衍生物结构来检测抗体，抗体片段或其工程变体的方法
公开(公告)号：WO2015117984A1
公开(公告)日：2015-08-13
申请号：PCT/EP2015/052246
申请日：2015-02-04
Applicant: BASF SE
Inventor： FELLE, Max, Fabian , GRANSTRÖM, Mari , LINDER, David , KORDE, Shilpa, S. , SAMEL, Amarish
CPC classification number: C07K1/22 , B01J20/288 , B01J20/289 , B01J20/3085 , B01J20/3204 , B01J20/321 , B01J20/3212 , B01J20/3219 , B01J20/3261 , B01J2220/49 , C07K16/00 , C09B67/0097 , C09B69/101 , G01N33/583 , G01N33/6857
Abstract: The present invention relates to novel adsorbents applicable a process for the separation or purification of antibodies, antibody fragments or engineered variants thereof, which comprise anthraquinone dye ligands; corresponding purification processes; and corresponding analytical or preparative separation kits.
Abstract translation: 本发明涉及适用于分离或纯化包含蒽醌染料配体的抗体，抗体片段或其工程变体的方法的新型吸附剂; 相应的净化过程; 和相应的分析或制备分离试剂盒。
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公开(公告)号：WO2015000858A3
公开(公告)日：2015-01-08
申请号：PCT/EP2014/063876
申请日：2014-06-30
Applicant: BASF SE
Inventor： GRANSTRÖM, Mari , KINDLER, Alois , SPIESS, Antje , KLUGE, Stefanie , BONHAGE, Benjamin
IPC: C12P19/14
Abstract: Die Erfindung betrifft ein Verfahren zur Herstellung von Celluloseoligomeren (Cellooligomeren) unter Verwendung von Endoglucanasen und beta-glucosidase nach Vorbehandlung der Cellulose mit ionischer Flüssigkeit und die Verwendung der so hergestellten Oligomere auf verschiedenen technischen Gebieten.
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公开(公告)号：WO2013072277A2
公开(公告)日：2013-05-23
申请号：PCT/EP2012/072394
申请日：2012-11-12
Applicant: BASF SE , KINDLER, Alois , GRANSTRÖM, Mari , KRÖNER, Hubertus , KERN, Holger
Inventor： KINDLER, Alois , GRANSTRÖM, Mari , KRÖNER, Hubertus , KERN, Holger
IPC: D21H17/17
Abstract: AKD cellulosic composition obtainable by flowing a stream of a cellulosic suspension through a shearing device and in which a molten alkyl ketene dimer (AKD) is metered in to the stream of cellulosic suspension in or prior to the shearing device. The AKD cellulosic composition is particularly suitable in the manufacture of sized paper and paperboard.
Abstract translation: AKD纤维素组合物可通过使纤维素悬浮液的流动流过剪切装置而获得，并且其中在剪切装置中或之前将熔融烷基烯酮二聚体（AKD）计量加入到纤维素悬浮液流中。 AKD纤维素组合物特别适用于制造尺寸大的纸和纸板。
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公开(公告)号：WO2011086082A1
公开(公告)日：2011-07-21
申请号：PCT/EP2011/050305
申请日：2011-01-12
Applicant: BASF SE , GRANSTRÖM, Mari , MORMANN, Werner , FRANK, Petra
Inventor： GRANSTRÖM, Mari , MORMANN, Werner , FRANK, Petra
Abstract: A process for chlorinating polysaccharides or oligosaccharides, which comprises A) dissolving a polysaccharide or oligosaccharide in a solvent system which comprises at least one ionic liquid and B) reacting the polysaccharides or oligosaccharides with a chlorinating agent.
Abstract translation: 一种用于氯化多糖或寡糖的方法，其包括A）将多糖或寡糖溶解在包含至少一种离子液体的溶剂体系中，B）使多糖或寡糖与氯化剂反应。
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5.发明申请GENETICALLY MODIFIED MICROORGANISMS CAPABLE OF PRODUCING BETA-GLUCANS AND METHODS FOR PRODUCING BETA-GLUCANS 审中-公开能够生产β-葡聚糖的基因改造的微生物和用于生产β-葡聚糖的方法
公开(公告)号：WO2014006088A1
公开(公告)日：2014-01-09
申请号：PCT/EP2013/064024
申请日：2013-07-03
Applicant: WINTERSHALL HOLDING GMBH , BASF SE , BASF SCHWEIZ AG
Inventor： BROCKMANN, Beata , HEROLD, Andrea , ZELDER, Oskar , HAEFNER, Stefan , FLECK, Christian , SCHRÖDER, Hartwig , GRANSTRÖM, Mari , SCHMIDT, Julia, Kristiane
CPC classification number: C12P19/04 , C12N9/1051 , C12Y204/01034
Abstract: The present invention relates to genetically modified microorganisms capable of producing beta-glucans, characterized in that said genetically modified microorganism overexpresses (i) a polynucleotide encoding a polypeptide having 1,3-β-D-glucan synthase-activity, and/or (ii) a polypeptide having 1,3-β-glucan synthase-activity, compared to a corresponding non-modified control microorganism of the same strain. The present invention also relates to the use of a polynucleotide encoding a polypeptide having 1,3-β-D-glucan synthase-activity or the use of such a polypeptide for producing β-glucans. Furthermore, the present invention relates to methods for producing β-glucans comprising the introduction of a promoter upstream of a polynucleotide encoding a polypeptide having 1,3-β-D-glucan synthase-activity thereby increasing the expression of said polynucleotide, or a polynucleotide encoding a polypeptide having 1,3-β-D-glucan synthase-activity into a microorganism being able to synthesize β-glucans.
Abstract translation: 本发明涉及能够产生β-葡聚糖的转基因微生物，其特征在于所述遗传修饰的微生物过表达（i）编码具有1,3-β-D-葡聚糖合酶活性的多肽的多核苷酸和/或（ii ）具有1,3-β-葡聚糖合酶活性的多肽，与相同菌株的相应未修饰的对照微生物相比较。 本发明还涉及编码具有1,3-β-D-葡聚糖合酶活性的多肽的多核苷酸的用途或这种多肽用于产生β-葡聚糖的用途。 此外，本发明涉及生产β-葡聚糖的方法，包括在编码具有1,3-β-D-葡聚糖合酶活性的多肽的多核苷酸上游引入启动子，从而增加所述多核苷酸的表达，或多核苷酸 将具有1,3-β-D-葡聚糖合酶活性的多肽编码成能够合成β-葡聚糖的微生物。
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Patent Agency Ranking
公开(公告)号：WO2013053630A1
公开(公告)日：2013-04-18
申请号：PCT/EP2012/069614
申请日：2012-10-04
Applicant: BASF SE
Inventor： GRANSTRÖM, Mari , WENDEL, Volker , WENDEL, Volker , WOOD, Claudia , VÖLLMAR, Helmuth , KNAB, Anni , KINDLER, Alois , ZAJACZKOWSKI-FISCHER, Marta
Abstract: The present invention relates to oligo- and polysaccharides containing amine groups. More particularly, the present invention is directed towards a new process to manufacture cationic cellulose oligomers. The new cationic oligo- or polysaccharides are shown to be useful ingredients in various aqueous compositions, inter alia as ingredients for personal care compositions.
Abstract translation: 本发明涉及含有胺基团的寡糖和多糖。 更具体地说，本发明涉及制造阳离子纤维素低聚物的新方法。 新的阳离子寡聚物或多糖被证明是各种水性组合物中的有用成分，特别是作为个人护理组合物的成分。
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公开(公告)号：EP2870239B1
公开(公告)日：2018-10-31
申请号：EP13734062.6
申请日：2013-07-03
Applicant: Wintershall Holding GmbH , BASF SE
Inventor： BROCKMANN, Beata , HEROLD, Andrea , ZELDER, Oskar , HAEFNER, Stefan , FLECK, Christian , SCHRÖDER, Hartwig , GRANSTRÖM, Mari , SCHMIDT, Julia, Kristiane
CPC classification number: C12P19/04 , C12N9/1051 , C12Y204/01034
Abstract: The present invention relates to genetically modified microorganisms capable of producing beta-glucans, characterized in that said genetically modified microorganism overexpresses (i) a polynucleotide encoding a polypeptide having 1,3-&bgr;-D-glucan synthase-activity, and/or (ii) a polypeptide having 1,3-&bgr;-D-glucan synthase-activity, compared to a corresponding non-modified control microorganism of the same strain. The present invention also relates to the use of a polynucleotide encoding a polypeptide having 1,3-&bgr;-D-glucan synthase-activity or the use of such a polypeptide for producing &bgr;-glucans. Furthermore, the present invention relates to methods for producing &bgr;-glucans comprising the introduction of a promoter upstream of a polynucleotide encoding a polypeptide having 1,3-&bgr;-D-glucan synthase-activity thereby increasing the expression of said polynucleotide, or a polynucleotide encoding a polypeptide having 1,3-&bgr;-D-glucan synthase-activity into a microorganism being able to synthesize &bgr;-glucans.
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8.发明公开METHOD FOR PURIFICATION OF ANTIBODIES, ANTIBODY FRAGMENTS OR ENGINEERED VARIANTS THEREOF USING SPECIFIC ANTHRAQUINONE DYE-LIGAND STRUCTURES 有权清洗过程抗体，抗体片段或特定蒽醌染料配位结构的IT操作VERSIONS
公开(公告)号：EP3102637A1
公开(公告)日：2016-12-14
申请号：EP15704492.6
申请日：2015-02-04
Applicant: BASF SE
Inventor： FELLE, Max Fabian , GRANSTRÖM, Mari , LINDER, David , KORDE, Shilpa S. , SAMEL, Amarish
CPC classification number: C07K1/22 , B01J20/288 , B01J20/289 , B01J20/3085 , B01J20/3204 , B01J20/321 , B01J20/3212 , B01J20/3219 , B01J20/3261 , B01J2220/49 , C07K16/00 , C09B67/0097 , C09B69/101 , G01N33/583 , G01N33/6857
Abstract: The present invention relates to novel adsorbents applicable a process for the separation or purification of antibodies, antibody fragments or engineered variants thereof, which comprise anthraquinone dye ligands; corresponding purification processes; and corresponding analytical or preparative separation kits.
Abstract translation: 本发明涉及适用新吸附剂为抗体，抗体片段的分离或纯化方法或其改造的变体，其包含蒽醌染料配体; CORRESPONDING纯化过程; 和相应的分析或制备分离试剂盒。
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公开(公告)号：EP2523977A1
公开(公告)日：2012-11-21
申请号：EP11700099.2
申请日：2011-01-12
Applicant: BASF SE , Universität Siegen
Inventor： GRANSTRÖM, Mari , MORMANN, Werner , FRANK, Petra
Abstract: A process for chlorinating polysaccharides or oligosaccharides, which comprises A) dissolving a polysaccharide or oligosaccharide in a solvent system which comprises at least one ionic liquid and B) reacting the polysaccharides or oligosaccharides with a chlorinating agent.
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10.发明公开ENDOGLUCANASE-INDUZIERTE HERSTELLUNG VON CELLULOSEOLIGOMEREN 审中-公开内酰胺酶-IUUZIERTE HERSTELLUNG VON CELLULOSEOLIGOMEREN
公开(公告)号：EP3017056A2
公开(公告)日：2016-05-11
申请号：EP14733666.3
申请日：2014-06-30
Applicant: BASF SE
Inventor： GRANSTRÖM, Mari , KINDLER, Alois , SPIESS, Antje , KLUGE, Stefanie , BONHAGE, Benjamin
IPC: C12P19/14
CPC classification number: C12P19/14 , A23K20/163 , A61K8/66 , A61K8/731 , A61K2800/10 , A61Q19/00 , C11D3/22 , C11D3/222 , C12P19/04 , C12Y302/01004
Abstract: The invention relates to a method for the production of cellulose oligomers (cellooligomers) using endoglucanases and to the use of the thus produced oligomers in different technical fields.
Abstract translation: 本发明涉及使用内切葡聚糖酶生产纤维素低聚物（纤维寡聚体）的方法以及在所生产的低聚物的各种技术领域中的用途。
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