公开(公告)号：CA2877030A1

公开(公告)日：2013-12-27

申请号：CA2877030

申请日：2013-06-18

Applicant: BASF SE

Inventor： CHIODO TIZIANA ,  HELLMANN ROLF ,  VOSSEN MARCUS ,  SALVADOR BEATE ,  HAFNER ANDREAS ,  HINTERMANN TOBIAS

IPC: C07D401/04 ,  A61K31/505 ,  A61P35/02

Abstract: Novel solid forms of imatinib mesilate comprising as active ingredient 4-[(4-methyl-1- piperazinyl) methyl] N [4-methyl-3-[ [4-(3-pyridinyl)-2-pyrimidinyl] amino]-phenyl]- benzamide methanesulfonic acid saltand as co-crystal former benzoic acid, fumaric acid or succinic acid are described. The said multi-component crystalline forms possess improved physical and biological properties with respect to the crystalline forms of the active pharmaceutical ingredient previously known.

公开(公告)号：CA3099875A1

公开(公告)日：2019-12-19

申请号：CA3099875

申请日：2019-05-29

Applicant: BASF SE

Inventor： VIERTELHAUS MARTIN ,  HELLMANN ROLF ,  SEISER TOBIAS ,  ZAGAR CYRILL ,  ARMEL GREGORY ,  STEINBRENNER ULRICH

IPC: C07D239/54 ,  A01N43/54

Abstract: The present invention relates to one crystalline form A of ethyl 2-[2-[2-chloro-4-fluoro-5-[3-methyl- 2,6-dioxo-4-(trifluoromethyl)pyrimidin-1-yl]phenoxy]phenoxy]acetate, a process for the production of this crystalline form, formulations for plant protection and herbicidal compositions comprising such form A.

公开(公告)号：CA3080449A1

公开(公告)日：2019-05-31

申请号：CA3080449

申请日：2018-11-08

Applicant: BASF SE

Inventor： VIERTELHAUS MARTIN ,  HELLMANN ROLF ,  KOULELIS DENNIS ,  SEISER TOBIAS

IPC: C07D403/14 ,  A01N43/54

Abstract: The present invention relates to crystalline forms of ethyl 2-[[3-[[3-chloro-5-fluoro-6-[3- methyl-2,6-dioxo-4-(trifluoromethyl)pyrimidin-1-yl]-2-pyridyl]oxy]-2-pyridyl]oxy]acetate, herein after also referred to as "compound of formula (I)". The invention also relates to a process for the production of these crystalline forms, formulations for plant protection and herbicidal compositions which contain one of these crystalline forms

公开(公告)号：CA2955570A1

公开(公告)日：2016-02-11

申请号：CA2955570

申请日：2015-08-03

Applicant: BASF SE

Inventor： VIERTELHAUS MARTIN ,  CHIODO TIZIANA ,  SALVADOR BEATE ,  VOSSEN MARCUS ,  HAFNER ANDREAS ,  HINTERMANN TOBIAS ,  WEISHAAR WALTER ,  HELLMANN ROLF

IPC: C07D213/40

Abstract: The present invention primarily relates to multi-component crystals comprising a compound of formula 1 and a second compound selected from the group consisting of co-crystal formers and sol-vents. The invention is further related to pharmaceutical compositions comprising such multi-component crystals. Furthermore, the invention relates to processes for preparing said multi-component crystals. The invention also relates to several aspects of using said multi-component crystals or pharmaceutical compositions to treat a disease.

公开(公告)号：AU2009289244A1

公开(公告)日：2010-03-11

申请号：AU2009289244

申请日：2009-09-04

Applicant: BASF SE

Inventor： PLATSCH HERBERT ,  SCHIFFER HELMUT ,  HELLMANN ROLF ,  EMIG STEFAN ,  GRABARSE WOLFGANG ,  KOHLE HARALD ,  GROSSMANN KLAUS ,  LANGEWALD JURGEN ,  BOEDDINGHAUS CHRISTINE ,  DORSCH JOHN

IPC: G01N33/68 ,  G01N33/50 ,  G06F17/00

Abstract: The present invention relates to a method for testing a substance or a substance mixture and the use thereof for identifying and/or characterizing the mode of action of the substance or the substance mixture or for determining the biochemical and/or metabolic state of an organism or group of organisms or part(s) thereof after exposure to the substance or the substance mixture.

公开(公告)号：AU2018373514A1

公开(公告)日：2020-05-14

申请号：AU2018373514

申请日：2018-11-08

Applicant: BASF SE

Inventor： VIERTELHAUS MARTIN ,  HELLMANN ROLF ,  KOULELIS DENNIS ,  SEISER TOBIAS

IPC: C07D403/14 ,  A01N43/54

Abstract: The present invention relates to crystalline forms of ethyl 2-[[3-[[3-chloro-5-fluoro-6-[3- methyl-2,6-dioxo-4-(trifluoromethyl)pyrimidin-1-yl]-2-pyridyl]oxy]-2-pyridyl]oxy]acetate, herein after also referred to as "compound of formula (I)". The invention also relates to a process for the production of these crystalline forms, formulations for plant protection and herbicidal compositions which contain one of these crystalline forms

公开(公告)号：AU2013242103A1

公开(公告)日：2014-10-16

申请号：AU2013242103

申请日：2013-03-20

Applicant: BASF SE

Inventor： CHIODO TIZIANA ,  KLIMOV EVGUENI ,  SCHAFER ANSGAR ,  HOFFKEN HANS WOLFGANG ,  HELLMANN ROLF ,  KABAT ANDRE ,  ISRAELS RAFEL ,  SCHNABEL GERHARD ,  BRATZ MATTHIAS ,  KIBAT CHRISTINE ,  HOUY WOLFGANG

IPC: A01N37/40 ,  A01N25/12 ,  A01P13/00 ,  C07C63/06 ,  C07D239/42 ,  C07D239/47 ,  C07D277/40 ,  C07D473/12

Abstract: Co-crystals comprising a) a herbicide compound A, which is 3,6-dichloro-2-methoxybenzoic acid (dicamba), and b) a co-crystal former B, which is selected from the group of aromatic, N- containing heterocycles; and their use in agrochemical compositions.

公开(公告)号：CA2867504A1

公开(公告)日：2013-10-03

申请号：CA2867504

申请日：2013-03-20

Applicant: BASF SE

Inventor： CHIODO TIZIANA ,  KLIMOV EVGUENI ,  SCHAFER ANSGAR ,  HOFFKEN HANS WOLFGANG ,  HELLMANN ROLF ,  KABAT ANDRE ,  ISRAELS RAFEL ,  SCHNABEL GERHARD ,  BRATZ MATTHIAS ,  KIBAT CHRISTINE ,  HOUY WOLFGANG

IPC: A01N37/40 ,  A01N25/12 ,  A01P13/00 ,  C07C63/06 ,  C07D239/42 ,  C07D239/47 ,  C07D277/40 ,  C07D473/12

Abstract: Co-crystals comprising a) a herbicide compound A, which is 3,6-dichloro-2-methoxybenzoic acid (dicamba), and b) a co-crystal former B, which is selected from the group of aromatic, N- containing heterocycles; and their use in agrochemical compositions.

公开(公告)号：NZ591163A

公开(公告)日：2012-08-31

申请号：NZ59116309

申请日：2009-09-04

Applicant: BASF SE

Inventor： PLATSCH HERBERT ,  SCHIFFER HELMUT ,  HELLMANN ROLF ,  EMIG STEFAN ,  GRABARSE WOLFGANG ,  KOHLE HARALD ,  GROSSMANN KLAUS ,  LANGEWALD JURGEN ,  BOEDDINGHAUS CHRISTINE ,  DORSCH JOHN

IPC: G01N33/68 ,  G01N33/50 ,  G06F17/00

Abstract: Disclosed is a method for testing a substance or a substance mixture and the use thereof for identifying and/or characterizing the mode of action of the substance or the substance mixture or for determining the biochemical and/or metabolic state of an organism or group of organisms or part(s) thereof after exposure to the substance or the substance mixture.

公开(公告)号：CA2735390A1

公开(公告)日：2010-03-11

申请号：CA2735390

申请日：2009-09-04

Applicant: BASF SE

Inventor： PLATSCH HERBERT ,  SCHIFFER HELMUT ,  HELLMANN ROLF ,  EMIG STEFAN ,  GRABARSE WOLFGANG ,  KOEHLE HARALD ,  GROSSMANN KLAUS ,  LANGEWALD JUERGEN ,  BOEDDINGHAUS CHRISTINE ,  DORSCH JOHN

IPC: G01N33/68 ,  G01N33/50 ,  G06F17/00

Abstract: The present invention relates to a method for testing a substance or a substance mixture and the use thereof for identifying and/or characterizing the mode of action of the substance or the substance mixture or for determining the biochemical and/or metabolic state of an organism or group of organisms or part(s) thereof after exposure to the substance or the substance mixture.