公开(公告)号：AT474557T

公开(公告)日：2010-08-15

申请号：AT05024161

申请日：2005-11-05

Applicant: BASF SE

Inventor： LISA RUDOLPH ERNEST ,  QUADIR ANISUL ,  HAM SCHEPER REBECCA ,  GRZESIOWSKI PETER

IPC: A61K9/14

Abstract: A method for formation of micro-prilled poloxamer particles is disclosed. The particles find special use in pharmaceutical formulations. The process involves use of atomizing nozzles at higher than normal pressure atomizing gas, high atomizing gas temperature, use of high feed temperatures to reduce the viscosity of the poloxamer and optionally sieving after prill formation in prilling towers. The poloxamer particles are spherical and preferably have an average nominal diameter of less than or equal to 106 microns. The process is very cost effective and rapid.

公开(公告)号：DE602005022396D1

公开(公告)日：2010-09-02

申请号：DE602005022396

申请日：2005-11-05

Applicant: BASF CORP ,  BASF SE

Inventor： LISA RUDOLPH ERNEST ,  QUADIR ANISUL ,  HAM SCHEPER REBECCA ,  GRZESIOWSKI PETER

IPC: A61K9/14