公开(公告)号：AU2006310551B2

公开(公告)日：2011-10-20

申请号：AU2006310551

申请日：2006-10-26

Applicant: BASF SE

Inventor： MARCUS KNELL ,  MONIKA BRINK ,  HENDRIK WEVERS JAN

IPC: C07D213/81 ,  C07D213/79

Abstract: The invention relates to a process for the preparation of pyridylcarboxylic amides and esters I, Formula (I) wherein Hal, X and R have the meanings given in claim 1, which comprises the following steps: (a) heating a mixture consisting essentially of trichloromethylpyridine II, Formula (II), wherein Hal has the meaning given, and 1.0 to 1.5 equivalents of concentrated sulfuric acid, characterized in that the trichloromethylpyridine II in a liquid form is added to the concentrated sulfuric acid at a temperature from 110°C to 160°C; and (b) reacting the intermediate product obtained in step (a) with an amine or alcohol III, HXR, wherein X and R have the meaning given, optionally in the presence of a solvent and/or a base.

公开(公告)号：ZA200804849B

公开(公告)日：2009-11-25

申请号：ZA200804849

申请日：2008-06-04

Applicant: BASF SE

Inventor： MARCUS KNELL ,  WEVERS JAN HENDRIK ,  MONIKA BRINK

IPC: C07D20100101

Abstract: The invention relates to a process for the preparation of pyridylcarboxylic amides and esters I, Formula (I) wherein Hal, X and R1 have the meanings given in claim 1, which comprises the following steps: (a) heating a mixture consisting essentially of trichloromethylpyridine II, Formula (II), wherein Hal has the meaning given, and 1.0 to 1.5 equivalents of concentrated sulfuric acid, characterized in that the trichloromethylpyridine II in a liquid form is added to the concentrated sulfuric acid at a temperature from 110° C. to 160° C.; and (b) reacting the intermediate product obtained in step (a) with an amine or alcohol III, HXR1, wherein X and R1 have the meaning given, optionally in the presence of a solvent and/or a base.