Process for the preparation of pyridylcarbroxylic amides and esters

    公开(公告)号:ZA200804849B

    公开(公告)日:2009-11-25

    申请号:ZA200804849

    申请日:2008-06-04

    Applicant: BASF SE

    Abstract: The invention relates to a process for the preparation of pyridylcarboxylic amides and esters I, Formula (I) wherein Hal, X and R1 have the meanings given in claim 1, which comprises the following steps: (a) heating a mixture consisting essentially of trichloromethylpyridine II, Formula (II), wherein Hal has the meaning given, and 1.0 to 1.5 equivalents of concentrated sulfuric acid, characterized in that the trichloromethylpyridine II in a liquid form is added to the concentrated sulfuric acid at a temperature from 110° C. to 160° C.; and (b) reacting the intermediate product obtained in step (a) with an amine or alcohol III, HXR1, wherein X and R1 have the meaning given, optionally in the presence of a solvent and/or a base.

    Process for the preparation of pyridylcarboxylic amides and esters

    公开(公告)号:AU2006310551B2

    公开(公告)日:2011-10-20

    申请号:AU2006310551

    申请日:2006-10-26

    Applicant: BASF SE

    Abstract: The invention relates to a process for the preparation of pyridylcarboxylic amides and esters I, Formula (I) wherein Hal, X and R have the meanings given in claim 1, which comprises the following steps: (a) heating a mixture consisting essentially of trichloromethylpyridine II, Formula (II), wherein Hal has the meaning given, and 1.0 to 1.5 equivalents of concentrated sulfuric acid, characterized in that the trichloromethylpyridine II in a liquid form is added to the concentrated sulfuric acid at a temperature from 110°C to 160°C; and (b) reacting the intermediate product obtained in step (a) with an amine or alcohol III, HXR, wherein X and R have the meaning given, optionally in the presence of a solvent and/or a base.

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