公开(公告)号：MY191883A

公开(公告)日：2022-07-18

申请号：MYPI2019001715

申请日：2017-10-05

Applicant: BASF SE

Inventor： SEBASTIAN WLOCH ,  GUNNAR HEYDRICH ,  MATTHIAS RAULUS

IPC: C07B57/00 ,  C07C29/78

Abstract: The present invention relates to a process for enriching enantiomers from an enantio-mer mixture by a fractionating melt crystallization in a melt crystallization apparatus. The invention specifically relates to a process for producing an enantiomer-enriched chiral terpene, in particular of D/L-lsopulegol. The process comprises: i) a crystallization step to obtain a crystallizate and a mother melt and removal of the mother melt from the crystallizate to afford a mother melt fraction; ii) sweating of the crystallizate obtained in step i) to afford a molten sweating frac-tion and iii) subsequent melting of the sweated crystallizate to afford a molten crystallizate fraction, wherein the optical rotation at least of the sweating fraction is determined online using a polarimeter and the changeover from step ii) to step iii) is controlled online by means of at least one control unit. (No suitable figure)