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公开(公告)号：WO2010115797A1
公开(公告)日：2010-10-14
申请号：PCT/EP2010/054284
申请日：2010-03-31
Applicant: BASF SE , PIATESI, Andrea , HABICHER, Tilo , BÜSCHEL, Michael , WANG, Li-Wen , REICHERT, Jürgen , PACKE-WIRTH, Rainer , BALDENIUs, Kai-Uwe , KROMM, Erich , HAEFNER, Stefan , SCHWALB, Carsten , HÖFFKEN, Hans Wolfgang
Inventor： PIATESI, Andrea , HABICHER, Tilo , BÜSCHEL, Michael , WANG, Li-Wen , REICHERT, Jürgen , PACKE-WIRTH, Rainer , BALDENIUs, Kai-Uwe , KROMM, Erich , HAEFNER, Stefan , SCHWALB, Carsten , HÖFFKEN, Hans Wolfgang
CPC classification number: C12N9/0008 , C11D3/38654 , C12N15/63 , C12P7/00 , D06M15/423 , D06M16/003 , D06P1/0004 , D06P1/56
Abstract: The invention relates to the use of an enzyme preparation which catalyzes the degradation of formaldehyde for reducing the formaldehyde content in a formaldehyde-containing formulation. In a preferred embodiment, the enzyme preparation contains a formaldehyde dismutase from a Pseudomonas putida strain. Further, the invention refers to a process for reducing the formal dehyde content in cross-linking agents for textile finishing or in polymer dispersions used, e.g. in construction chemistry. Further the invention relates to the use of an enzyme preparation which catalyzes the degradation of aldehydes for reducing the formaldehyde content in an aldehyde-containing formulation. Furthermore, the invention relates to a novel variant of the formaldehyde dismutase from Pseudomonas putida.
Abstract translation: 本发明涉及催化甲醛降解以降低含甲醛制剂中的甲醛含量的酶制剂的用途。 在优选的实施方案中，酶制剂含有恶臭假单胞菌菌株的甲醛歧化酶。 此外，本发明涉及用于降低用于纺织品整理的交联剂或所用聚合物分散体中的正式脱水含量的方法，例如， 在建筑化学。 此外，本发明涉及催化醛降解以降低含醛制剂中的甲醛含量的酶制剂的用途。 此外，本发明涉及恶臭假单胞菌的甲醛歧化酶的新型变体。
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2.发明申请METHOD OF CULTIVATING MICROORGANISMS HAVING NITRILE HYDRATASE ACTIVITY 审中-公开培养具有NITRILE HYDRATASE活性的微生物的方法
公开(公告)号：WO2016050861A1
公开(公告)日：2016-04-07
申请号：PCT/EP2015/072594
申请日：2015-09-30
Applicant: BASF SE
Inventor： HAGE, Kerstin , SCHWALB, Carsten , SPRÖTE, Petra , ÖDMAN, Peter , BALDENIUS, Kai-Uwe , ERNST, Burkhard , STEIGELMANN, Gunter , FREYER, Stephan , BOLLSCHWEILER, Claus , BRAUN, Michael Günter , DAEUWEL, Juergen
CPC classification number: C12N9/88 , C12N1/20 , C12N1/38 , C12Y402/01084
Abstract: The present invention relates to methods for cultivating a nitrile hydratase producing microorganism, compositions for cultivating a nitrile hydratase producing microorganism, and use of compositions comprising a saccharide and an organic acid for cultivating a nitrile hydratase producing microorganism. The composition provided in and to be employed in context with the present invention is particularly suitable for inducing both, growth and nitrile hydratase production of corresponding microorganisms.
Abstract translation: 本发明涉及培养腈水合酶产生微生物的方法，用于培养腈水合酶产生微生物的组合物，以及使用含有糖和有机酸的组合物来培养腈水合酶产生微生物。 在本发明中提供和使用的组合物特别适用于诱导相应微生物的生长和腈水合酶的生产。
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公开(公告)号：WO2018011242A1
公开(公告)日：2018-01-18
申请号：PCT/EP2017/067474
申请日：2017-07-12
Applicant: BASF SE
Inventor： HAGE, Kerstin , SCHWALB, Carsten , STEIGELMANN, Gunter , KAEDING, Thomas , BRIECHLE, Sebastian
Abstract: The present invention is directed to a fermentation medium and a fermentation method using said fermentation medium wherein the fermentation medium comprising a basal medium and a chelating agent having the formula (I) R 1 -CH(COOX 1 )-N(CH 2 COOX 1 ) 2 , wherein R 1 is selected from hydrogen, linear or branched C 1 -C 4 -alkyl, phenyl, benzyl, CH 2 OH, and CH 2 CH 2 COOX 1 , X 1 is (Μ x Η 1-x ), M being a monovalent cation, preferably being selected from ammonium or alkali metal or combinations of at least two of the foregoing, x is in the range of from zero to 1, wherein x is an average value.
Abstract translation: 本发明涉及发酵培养基和使用所述发酵培养基的发酵方法，其中发酵培养基包含基础培养基和具有式（I）R1的螯合剂， -CH（COOX 1）-N（CH 2）COOX 1）2，其中R 1选自氢，直链或支链C 1 -C 4 - 烷基，苯基，苄基，CH 2 OH ，并且CH 2 = CH 2 COOX 1，X 1是（M x = H是1价阳离子，优选选自铵或碱金属或前述至少两种的组合，x在0-1的范围内，其中x 是一个平均值。
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公开(公告)号：WO2017055587A1
公开(公告)日：2017-04-06
申请号：PCT/EP2016/073479
申请日：2016-09-30
Applicant: BASF SE , BASF S.A. CONDOMINIO ROCHAVERÁ, TORRE CRYSTAL
Inventor： FELLE, Max Fabian , SCHWALB, Carsten , HÜMMERICH, Daniel , FEHR, Markus
CPC classification number: C07K14/463 , C07K14/43563 , C07K2319/00 , C07K2319/20 , C07K2319/40
Abstract: Die vorliegende Erfindung betrifft neuartige repetitive selbstassemblierende Vorläuferproteine, dafür kodierende Nukleinsäuresequenzen und Expressionskonstrukte, sowie Verfahren zur rekombinanten Herstellung von Peptiden unter Verwendung von solchen Vorläuferproteinen.
Abstract translation: 本发明涉及新的重复自组装前体蛋白，核酸编码序列和表达构建体，以及用于重组产生使用这样的前体蛋白的肽的方法。
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公开(公告)号：WO2010139736A2
公开(公告)日：2010-12-09
申请号：PCT/EP2010/057726
申请日：2010-06-02
Applicant: BASF SE , HÜMMERICH, Daniel , LIEBMANN, Burghard , FEHR, Markus , SCHWALB, Carsten , BRÜSER, Heike
Inventor： HÜMMERICH, Daniel , LIEBMANN, Burghard , FEHR, Markus , SCHWALB, Carsten , BRÜSER, Heike
IPC: C07K14/00
CPC classification number: C07K14/4723 , C07K2319/00 , C07K2319/50 , C12N15/62 , C12P21/06
Abstract: Die vorliegende Erfindung betrifft repetitive selbstassemblierende Vorläuferproteine, dafür kodierende Nukleinsäuresequenzen und Expressionskonstrukte, sowie Verfahren zur rekombinanten Herstellung von Peptiden unter Verwendung von solchen Vorläuferproteinen.
Abstract translation: 本发明涉及重复自组装前体蛋白，核酸编码序列和表达构建体，以及用于重组产生使用这样的前体蛋白的肽的方法。
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Patent Agency Ranking
公开(公告)号：WO2010139539A1
公开(公告)日：2010-12-09
申请号：PCT/EP2010/056536
申请日：2010-05-12
Applicant: BASF SE , BRÜSER, Heike , HÜMMERICH, Daniel , BOLLSCHWEILER, Claus , SCHWALB, Carsten
Inventor： BRÜSER, Heike , HÜMMERICH, Daniel , BOLLSCHWEILER, Claus , SCHWALB, Carsten
CPC classification number: A61K38/1729 , C07K14/4723 , Y02A50/475
Abstract: Die Erfindung betrifft eine pharmazeutische Zusammensetzung, enthaltend in einem pharmazeutischen Träger ein Peptid, das wenigstens ein Sequenzmotiv folgender allgemeiner Formel (I) Hel1 - HB - Hel2 umfasst, sowie die Verwendung und Herstellung dieser pharmazeutischen Zusammensetzungen.
Abstract translation: 本发明涉及包括在包含下述通式（I）HEL1中的至少一个序列基序的肽的药物载体的药物组合物 - HB - Hel2包括，以及使用和制备这些药物组合物。
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公开(公告)号：EP3484996A1
公开(公告)日：2019-05-22
申请号：EP17736682.0
申请日：2017-07-12
Applicant: BASF SE
Inventor： HAGE, Kerstin , SCHWALB, Carsten , STEIGELMANN, Gunter , KAEDING, Thomas , BRIECHLE, Sebastian
Abstract: The present invention is directed to a fermentation medium and a fermentation method using said fermentation medium wherein the fermentation medium comprising a basal medium and a chelating agent having the formula (I) R1—CH(COOX1)—N(CH2COOX1)2, wherein R1 is selected from hydrogen, linear or branched C1-C4-alkyl, phenyl, benzyl, CH2OH, and CH2CH2COOX1, X1 is (MxH1-x), M being a monovalent cation, preferably being selected from ammonium or alkali metal or combinations of at least two of the foregoing, x is in the range of from zero to 1, wherein x is an average value.
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公开(公告)号：EP2437769A2
公开(公告)日：2012-04-11
申请号：EP10724472.5
申请日：2010-06-02
Applicant: BASF SE
Inventor： HÜMMERICH, Daniel , LIEBMANN, Burghard , FEHR, Markus , SCHWALB, Carsten , BRÜSER, Heike
CPC classification number: C07K14/4723 , C07K2319/00 , C07K2319/50 , C12N15/62 , C12P21/06
Abstract: The present invention relates to repetitive self-assembling precursor proteins, nucleic acid sequences and expression constructs encoding the same, and to methods for recombinant production of peptides using such precursor proteins.
Abstract translation: 本发明涉及重复的自组装前体蛋白，核酸序列和编码其的表达构建体，以及使用这种前体蛋白重组生成肽的方法。
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公开(公告)号：EP2429564A1
公开(公告)日：2012-03-21
申请号：EP10721448.8
申请日：2010-05-12
Applicant: BASF SE
Inventor： BRÜSER, Heike , HÜMMERICH, Daniel , BOLLSCHWEILER, Claus , SCHWALB, Carsten
CPC classification number: A61K38/1729 , C07K14/4723 , Y02A50/475
Abstract: The invention relates to a pharmaceutical composition containing, in a pharmaceutical carrier, a peptide comprising at least one sequence motif of the following general formula (I) Hel1 - HB - Hel2. The invention also relates to the use and production of said pharmaceutical compositions.
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公开(公告)号：EP3484996B1
公开(公告)日：2020-09-09
申请号：EP17736682.0
申请日：2017-07-12
Applicant: BASF SE
Inventor： HAGE, Kerstin , SCHWALB, Carsten , STEIGELMANN, Gunter , KAEDING, Thomas , BRIECHLE, Sebastian
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