METHODS FOR DETERMINING MODULATORS OF INSECT TRANSIENT RECEPTOR POTENTIAL V (TRPV) CHANNEL
    1.
    发明申请
    METHODS FOR DETERMINING MODULATORS OF INSECT TRANSIENT RECEPTOR POTENTIAL V (TRPV) CHANNEL 审中-公开
    确定瞬时受体电位V(TRPV)通道的调节剂的方法

    公开(公告)号:WO2015097560A3

    公开(公告)日:2015-11-26

    申请号:PCT/IB2014003205

    申请日:2014-12-19

    Applicant: BASF SE

    Abstract: The present invention relates to a screening method for determining whether or not a candidate compound is a modulator of an insect transient receptor potential V (TRPV) channel. The present invention further provides a method of insect control by applying to an insect- specific TRPV channel modulator determined by the screening method. The present invention further relates to an expression vector that includes a nucleic acid molecule coding for an insect TRPV channel. Also, the present invention relates to cell that includes the expression vector encoding a TRPV channel.

    Abstract translation: 本发明涉及一种用于确定候选化合物是否为昆虫瞬态受体电位V(TRPV)通道的调节剂的筛选方法。 本发明还提供了通过应用于通过筛选方法测定的昆虫特异性TRPV通道调节剂的昆虫防治方法。 本发明还涉及包含编码昆虫TRPV通道的核酸分子的表达载体。 此外,本发明涉及包含编码TRPV通道的表达载体的细胞。

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