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公开(公告)号：WO2007073526A2
公开(公告)日：2007-06-28
申请号：PCT/US2006061157
申请日：2006-11-21
Applicant: BAXTER INT , BAXTER HEALTHCARE SA , BACKES LARRY P , ANDERSON KEITH M
Inventor： BACKES LARRY P , ANDERSON KEITH M
CPC classification number: B65D75/30 , B65D1/095 , B65D75/58 , B65D75/5855 , B65D75/5866 , B65D81/3266
Abstract: A pliable single use liquid container and dispensing device for delivery of a precise amount of orally administered liquids across a broad range of viscosities is provide with the container being formed of generally opposed pliable sheets, a first seal joining the first and second pliable sheets and partially defining a liquid-containing chamber, a second seal joining the first and second pliable sheets and partially defining a pressure relieving chamber adjacent to the liquid-containing chamber, a boundary seal joining the first and second pliable sheets between the liquid containing chamber and the pressure relieving chamber, a precisely measured single dose volume of fluent liquid disposed within the liquid containing chamber, the boundary seal being lighter than the first and second seals so that upon application of pressure to the liquid in the liquid-containing chamber the fluid transfer region seal opens to permit the liquid to flow from the liquid- containing chamber into the pressure relieving chamber, a sealed outlet adapted for fluid communication with the pressure relieving chamber for flow of the liquid from the pressure relieving chamber out of the liquid container and sized based on the viscosity of the liquid and the geometry of the dispensing device, the outlet seal adapted to open upon application of fluid pressure from liquid in the pressure relieving chamber for dispensing the liquid from the liquid container and prevent spilling and splashing of the liquid prior to delivery, control the delivery rate of the liquid to the recipient, and provide tactile force flow rate information feedback to the administrator.
Abstract translation: 提供一种用于在宽范围的粘度下递送精确量的经口施用的液体的柔韧的一次性液体容器和分配装置，其中容器由大致相对的柔韧片形成，第一密封接合第一和第二柔韧片， 限定液体容纳室，第二密封件，其接合所述第一和第二柔性片材并且部分地限定邻近所述液体容纳室的减压室;边界密封件，其将所述第一和第二柔性片材在所述液体容纳室和所述压力容器 泄放室，设置在液体容纳室内的精确测量的单剂量体积的流体液体，边界密封件比第一和第二密封件轻，使得当对液体容纳室中的液体施加压力时，流体传送区域密封 打开以允许液体从含液体室流入p 一个密封出口，适合于与减压室流体连通的密封出口，用于使液体从压力释放室流出液体容器，并基于液体的粘度和分配装置的几何形状来定尺寸，出口 密封件适于在压力释放室中的液体施加流体压力时打开，用于从液体容器分配液体，并防止在输送之前液体溢出和飞溅，控制液体向接收器的传送速率，并提供触觉 强制流量信息反馈给管理员。
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公开(公告)号：CA2628799A1
公开(公告)日：2007-06-28
申请号：CA2628799
申请日：2006-11-21
Applicant: BAXTER HEALTHCARE SA , BAXTER INT
Inventor： BACKES LARRY P , ANDERSON KEITH M
Abstract: A pliable single use liquid container and dispensing device for delivery of a precise amount of orally administered liquids across a broad range of viscosities is provide with the container being formed of generally opposed pliable sheets, a first seal joining the first and second pliable sheets and partially defining a liquid-containing chamber, a second seal joining the first and second pliable sheets and partially defining a pressure relieving chamber adjacent to the liquid-containing chamber, a boundary seal joining the first and second pliable sheets between the liquid-containing chamber and the pressure relieving chamber, a precisely measured single dose volume of fluent liquid disposed within the liquid-containing chamber, the boundary seal being lighter than the first and second seals so that upon application of pressure to the liquid in the liquid-containing chamber the fluid transfer region seal opens to permit the liquid to flow from the liquid-containing chamber into the pressure relieving chamber, a sealed outlet adapted for fluid communication with the pressure relieving chamber for flow of the liquid from the pressure relieving chamber out of the liquid container and sized based on the viscosity of the liquid and the geometry of the dispensing device, the outlet seal adapted to open upon application of fluid pressure from liquid in the pressure relieving chamber for dispensing the liquid from the liquid container and prevent spilling and splashing of the liquid prior to delivery, control the delivery rate of the liquid to the recipient, and provide tactile force flow rate information feedback to the administrator.
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公开(公告)号：DE60129208T2
公开(公告)日：2008-03-06
申请号：DE60129208
申请日：2001-02-07
Applicant: BAXTER INT
Inventor： LING MICHAEL T , WOO LECON , WOJNAROWSKI ROBERT , SHAH KETAN , NEBGEN GREGG , DING YUAN-PANG SAMUEL , KALYANKAR VARSHA , ANDERSON KEITH M , ZAKARIJA LILLIAN G , CRAMER COLLEEN S , SCHARF MICHAEL , ROSENBAUM LARRY A
Abstract: The present invention provides a multiple layer thermoplastic structure of a (1) skin layer selected from the group consisting of polypropylene, ethylene homopolymers having a density of from about 0.930 g/cc to about 0.960 g/cc, and ethylene homopolymers having a density of from about 0.930 g/cc to about 0.960 g/cc blended with an ethylene and a-olefin copolymers having a density less than about 0.930 g/cc, the skin layer having a thickness of greater than about 3.0 mils; (2) a radio frequency susceptible layer adhered to the skin layer, the radio frequency susceptible layer having a dielectric loss greater than 0.05 at 1-60 MHz and at temperatures of ambient to 250° C., the radio frequency susceptible layer having: (a) a first polyolefin selected from the group consisting of polypropylene and polypropylene copolymers, (b) a second polyolefin selected from the group consisting of ethylene copolymers, ultra-low density polyethylene, polybutene, and butene ethylene copolymers; (c) a radio frequency susceptible polymer selected from the group consisting of (i) ethylene copolymers having 50-85% ethylene content with comonomers selected from a first group consisting of acrylic acid, methacrylic acid, ester derivatives of acrylic acid with alcohols having 1-10 carbons, ester derivatives of methacrylic acid with alcohols having 1-10 carbons, vinyl acetate, and vinyl alcohol (ii) homopolymers and copolymers containing at least one segment of urethanes, esters, ureas, imides, sulfones, and amides, and (d) a compatibilizing agent of a styrene and hydrocarbon copolymer; wherein the structure when fabricated into a 50 ml container has a water vapor transmission rate of less than 8% by weight after the container has been autoclaved at 121° C. for 20 minutes and stored for 90 days in an environmentally regulated compartment having 15% relative humidity at 40° C.
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公开(公告)号：DE60129208D1
公开(公告)日：2007-08-16
申请号：DE60129208
申请日：2001-02-07
Applicant: BAXTER INT
Inventor： LING MICHAEL T , WOO LECON , WOJNAROWSKI ROBERT , SHAH KETAN , NEBGEN GREGG , DING YUAN-PANG SAMUEL , KALYANKAR VARSHA , ANDERSON KEITH M , ZAKARIJA LILLIAN G , CRAMER COLLEEN S , SCHARF MICHAEL , ROSENBAUM LARRY A
Abstract: The present invention provides a multiple layer thermoplastic structure of a (1) skin layer selected from the group consisting of polypropylene, ethylene homopolymers having a density of from about 0.930 g/cc to about 0.960 g/cc, and ethylene homopolymers having a density of from about 0.930 g/cc to about 0.960 g/cc blended with an ethylene and a-olefin copolymers having a density less than about 0.930 g/cc, the skin layer having a thickness of greater than about 3.0 mils; (2) a radio frequency susceptible layer adhered to the skin layer, the radio frequency susceptible layer having a dielectric loss greater than 0.05 at 1-60 MHz and at temperatures of ambient to 250° C., the radio frequency susceptible layer having: (a) a first polyolefin selected from the group consisting of polypropylene and polypropylene copolymers, (b) a second polyolefin selected from the group consisting of ethylene copolymers, ultra-low density polyethylene, polybutene, and butene ethylene copolymers; (c) a radio frequency susceptible polymer selected from the group consisting of (i) ethylene copolymers having 50-85% ethylene content with comonomers selected from a first group consisting of acrylic acid, methacrylic acid, ester derivatives of acrylic acid with alcohols having 1-10 carbons, ester derivatives of methacrylic acid with alcohols having 1-10 carbons, vinyl acetate, and vinyl alcohol (ii) homopolymers and copolymers containing at least one segment of urethanes, esters, ureas, imides, sulfones, and amides, and (d) a compatibilizing agent of a styrene and hydrocarbon copolymer; wherein the structure when fabricated into a 50 ml container has a water vapor transmission rate of less than 8% by weight after the container has been autoclaved at 121° C. for 20 minutes and stored for 90 days in an environmentally regulated compartment having 15% relative humidity at 40° C.
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