公开(公告)号：WO9514739A3

公开(公告)日：1995-08-24

申请号：PCT/US9413342

申请日：1994-11-16

Applicant: BAXTER INT

Inventor： LAURIN DEAN ,  BUAN ANGELES LILLIAN ,  WOO LECON ,  LING MICHAEL T K ,  DING YUAN-PANG SAMUEL ,  ANDERSON WILLIAM ,  ROSENBAUM LARRY A ,  HAYWARD DENISE S ,  HOPPESCH JOSEPH P ,  NEBGEN GREGG ,  WESTPHAL STANLEY

IPC: A61L27/00 ,  A61L31/00 ,  C08L23/02 ,  C08L23/06 ,  C08L23/08 ,  C08L23/10 ,  C08L23/16 ,  C08L23/20 ,  C08L23/26 ,  C08L29/04 ,  C08L31/04 ,  C08L51/06 ,  C08L53/00 ,  C08L53/02 ,  C08L67/00 ,  C08L75/00 ,  C08L77/00 ,  C08L101/00 ,  C08L101/12 ,  C08L28/02

CPC classification number: C08L23/02 ,  C08L23/0815 ,  C08L23/0846 ,  C08L23/0853 ,  C08L23/0869 ,  C08L23/10 ,  C08L51/06 ,  C08L53/00 ,  C08L53/02 ,  C08L77/00 ,  C08L101/00 ,  C08L2203/02 ,  C08L2205/08 ,  C08L2666/04 ,  C08L2666/20 ,  C08L2666/14 ,  C08L2666/24 ,  C08L2666/02

Abstract: Multiple component polymer compositions for fabrication into articles. In particular, polymeric compositions comprising a heat resistant polymer; a radio frequency ('RF') susceptible polymer; a compatibilizing polymer; the composition having physical properties within the range a 1.0; e

公开(公告)号：WO0156783A8

公开(公告)日：2002-11-21

申请号：PCT/US0103993

申请日：2001-02-07

Applicant: BAXTER INT

Inventor： LING MICHAEL T K ,  WOO LECON ,  WOJNAROWSKI ROBERT ,  SHAH KETAN ,  NEBGEN GREGG ,  DING YUAN-PANG SAMUEL ,  KALYANKAR VARSHA ,  ANDERSON KEITH M K ,  ZAKARIJA LILLIAN G ,  CRAMER COLLEEN S ,  SCHARF MICHAEL ,  ROSENBAUM LARRY A

IPC: A61L31/00 ,  B32B27/08 ,  B32B27/32 ,  C08L23/08 ,  C08L23/10 ,  C08L25/04 ,  C08L53/00 ,  C08L53/02

CPC classification number: B32B27/08 ,  B29C47/0023 ,  B29C47/0026 ,  B29C47/061 ,  B32B7/02 ,  B32B27/306 ,  B32B27/32 ,  B32B27/34 ,  B32B2250/24 ,  B32B2307/7242 ,  B32B2323/043 ,  B32B2323/046 ,  B32B2329/04 ,  B32B2377/00 ,  B32B2535/00 ,  C08L23/08 ,  C08L23/0853 ,  C08L23/0869 ,  C08L23/10 ,  C08L25/04 ,  C08L53/00 ,  C08L53/02 ,  Y10T428/1314 ,  Y10T428/1379 ,  Y10T428/1383 ,  Y10T428/2874 ,  Y10T428/2878 ,  Y10T428/2883 ,  Y10T428/2887 ,  Y10T428/2891 ,  Y10T428/2896 ,  Y10T428/31573 ,  Y10T428/31587 ,  Y10T428/3175 ,  Y10T428/31757 ,  Y10T428/31909 ,  Y10T428/31913 ,  Y10T428/31917 ,  Y10T428/31924 ,  Y10T428/31928 ,  Y10T428/31931 ,  Y10T428/31935 ,  Y10T428/31938 ,  C08L2666/04

Abstract: The present invention provides a multiple layer thermoplastic structure of a (1) skin layer selected from the group consisting of polypropylene, ethylene homopolymers having a density of from about 0.930 g/cc to about 0.960 g/cc, and ethylene homopolymers having a density of from about 0.930 g/cc to about 0.960 c/cc blended with an ethylene and alpha -olefin copolymers having a density less than about 0.930 g/cc, the skin layer having a thickness of greater than about 3.0 mils; (2) a radio frequency susceptible layer adhered to the skin layer, the radio frequency susceptible layer having a dielectric loss greater than 0.05 at 1-60 MHz and at temperatures of ambient to 250 DEG C, the radio frequency susceptible layer having: (a) a first polyolefin selected from the group consisting of polypropylene and polypropylene copolymers, (b) a second polyolefin selected from the group consisting of ethylene copolymers, ultra-low density polyethylene, polybutene, and butene ethylene copolymers; (c) a radio frequency susceptible polymer selected from the group consisting of (i) ethylene copolymers having 50-85 % ethylene content with comonomers selected from a first group consisting of acrylic acid, methacrylic acid, ester derivatives of acrylic acid with alcohols having 1-10 carbons, ester derivatives of methacrylic acid with alcohols having 1-10 carbons, vinyl acetate, and vinyl alcohol (ii) homopolymers and copolymers containing at least one segment of urethanes, esters, ureas, imides, sulfones, and amides, and (d) a compatibilizing agent of a styrene and hydrocarbon copolymer; wherein the structure when fabricated into a 50 ml container has a water vapor transmission rate of less than 8 % by weight after the container has been autoclaved at 121 DEG C for 20 minutes and stored for 90 days in an environmentally regulated compartment having 15 % relative humidity at 40 DEG C.

Abstract translation: 本发明提供了选自聚丙烯，密度为约0.930g / cc至约0.960g / cc的乙烯均聚物的（1）表层的多层热塑性结构，以及密度为 约0.930g / cc至约0.960c / cc与乙烯和密度小于约0.930g / cc的α-烯烃共聚物共混，所述表层具有大于约3.0密耳的厚度; （2）粘附于皮肤层的无线电频率敏感层，在1-60MHz和环境温度至250℃的介电损耗大于0.05的无线电频率敏感层，所述射频敏感层具有：（a ）选自聚丙烯和聚丙烯共聚物的第一种聚烯烃，（b）选自乙烯共聚物，超低密度聚乙烯，聚丁烯和丁烯乙烯共聚物的第二种聚烯烃; （c）选自以下的射频敏感聚合物：（i）具有50-85％乙烯含量的共聚单体的乙烯共聚物选自丙烯酸，甲基丙烯酸，丙烯酸的酯衍生物与具有1个 -10碳，甲基丙烯酸与具有1-10个碳的醇的酯衍生物，乙酸乙烯酯和乙烯醇（ii）含有至少一个部分的氨基甲酸酯，酯，脲，酰亚胺，砜和酰胺的均聚物和共聚物和（ d）苯乙烯和烃共聚物的相容剂; 其中当制造成50ml容器时的结构在容器在121℃高压灭菌20分钟后具有小于8重量％的水蒸汽透过率，并在相对湿度为15％的环境调节室中储存90天 湿度在40℃

公开(公告)号：WO9915289A3

公开(公告)日：1999-06-17

申请号：PCT/US9819690

申请日：1998-09-18

Applicant: BAXTER INT

Inventor： SMITH SIDNEY T ,  ROSENBAUM LARRY A ,  GIOVANETTO STEVEN ,  BUCHANAN BRADLEY ,  DING Y SAMUEL ,  FAN SUCHUAN C ,  NEBGEN GREGG

IPC: A61J1/10 ,  B32B27/08 ,  B32B27/28 ,  A61J1/00

CPC classification number: B32B27/08 ,  B29C47/0021 ,  B29C47/0023 ,  B29C47/061 ,  B32B27/32 ,  B32B27/34 ,  B32B37/153 ,  B32B2323/046 ,  B32B2377/00 ,  B32B2535/00 ,  Y10T428/1379 ,  Y10T428/1383 ,  Y10T428/26 ,  Y10T428/28 ,  Y10T428/31725 ,  Y10T428/3175 ,  Y10T428/31855 ,  Y10T428/31909 ,  Y10T428/3192

Abstract: The present invention provides a multiple layer structure (10) for fabricating medical products. The layer structure (10) has a core layer (14) of an ethylene vinyl alcohol copolymer having an ethylene content of about 25-45 mole percent, a solution contact layer of a polyolefin positioned on a first side of the core layer, an outer (12) positioned on a second side of the core layer opposite the solution contact layer (16), the outer layer (12) being selected from the group consisting of polyamides, polyesters and polyolefins; two tie layers (18) - one of each adhered to the first and second sides of the core layer (14) and positioned between the solution contact layer (16) and the core layer (14) and between the outer layer (12) and the core layer (14), and wherein the structure (10) is produced in a cast coextrusion process.

Abstract translation: 本发明提供了用于制造医疗产品的多层结构（10）。 该层结构（10）具有乙烯含量约为25-45％（摩尔）的乙烯乙烯醇共聚物芯层（14），位于芯层第一侧的聚烯烃溶液接触层，外层 （12），其位于所述芯层的与所述溶液接触层（16）相对的第二侧上，所述外层（12）选自由聚酰胺，聚酯和聚烯烃组成的组; 两个连接层（18） - 每一个连接到芯层（14）的第一和第二侧并且位于溶液接触层（16）和芯层（14）之间以及外层（12）和 芯层（14），并且其中结构（10）以铸造共挤出工艺生产。

公开(公告)号：EP1556214A4

公开(公告)日：2007-03-21

申请号：EP02776382

申请日：2002-10-29

Applicant: BAXTER INT

Inventor： SMITH SIDNEY T ,  ROSENBAUM LARRY ,  GIOVANETTO STEVEN ,  NEBGEN GREGG

IPC: B32B27/32 ,  B32B27/34 ,  B32B27/36

CPC classification number: B32B27/34 ,  B32B27/32 ,  B32B27/36 ,  Y10T428/31725 ,  Y10T428/31786

Abstract: The present invention provides a multiple-layer structure for fabricating medical products. The multiple-layered structure has a first layer of a polyester; a second layer attached to the first layer, the second layer of an ethylene and alpha-olefin copolymer; and wherein the structure has a modulus of elasticity of less than about 60,000 psi.

公开(公告)号：EP2148775A4

公开(公告)日：2010-10-20

申请号：EP08755239

申请日：2008-05-09

Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA

Inventor： DING YUANPANG S ,  LING MICHAEL T ,  CHANG MOH-CHING O ,  VALLEE JEAN-MICHEL ,  NEBGEN GREGG

IPC: B32B1/08 ,  B32B15/08

CPC classification number: B32B27/08 ,  A61J1/10 ,  Y10T428/1352 ,  Y10T428/1379 ,  Y10T428/1383 ,  Y10T428/28 ,  Y10T428/2813 ,  Y10T428/2852 ,  Y10T428/287 ,  Y10T428/2891 ,  Y10T428/2896

公开(公告)号：EP1490220A4

公开(公告)日：2008-06-04

申请号：EP03716630

申请日：2003-03-17

Applicant: BAXTER INT

Inventor： NEBGEN GREGG ,  ANDERSON KEITH M K ,  SCHARF MICHAEL W

IPC: A61J1/10 ,  B32B7/02 ,  B32B27/06 ,  B32B27/08 ,  B32B27/32 ,  C08L23/08 ,  C08L23/10 ,  C08L25/04 ,  C08L53/00 ,  C08L53/02 ,  B32B27/30 ,  B32B27/34 ,  B32B27/36 ,  B32B27/40 ,  B32B27/42

CPC classification number: B29C47/061 ,  B29C47/0021 ,  B32B27/06 ,  B32B27/08 ,  B32B27/32 ,  C08L23/08 ,  C08L23/0853 ,  C08L23/0869 ,  C08L23/10 ,  C08L25/04 ,  C08L53/00 ,  C08L53/02 ,  Y10T428/1314 ,  Y10T428/1379 ,  Y10T428/1383 ,  Y10T428/2874 ,  Y10T428/2878 ,  Y10T428/2883 ,  Y10T428/2887 ,  Y10T428/2891 ,  Y10T428/2896 ,  Y10T428/31573 ,  Y10T428/31587 ,  Y10T428/31746 ,  Y10T428/3175 ,  Y10T428/31757 ,  Y10T428/31909 ,  Y10T428/31913 ,  Y10T428/31917 ,  Y10T428/31924 ,  Y10T428/31928 ,  Y10T428/31931 ,  Y10T428/31935 ,  Y10T428/31938 ,  C08L2666/04

Abstract: A multiple layer structure comprising a first and a second skin layer, each skin layer comprised of a polypropylene containing polymer, and a radio frequency ('RF') susceptible layer adhered to and between the first and second skin layers. The RF layer has a first component of a propylene based polymer, a second component of a non-propylene polyolefin, a third component of a radio frequency susceptible polymer, and a fourth component of a polymeric compatibilizing agent.

Abstract translation: 一种多层结构，包括第一和第二表层，含有聚合物的聚丙烯构成的每个表层，和一个射频（“RF”）敏感层粘附到与第一和第二表层之间。 所述RF层具有基于丙烯聚合物的第一组分，非丙烯的聚烯烃的第二部件，射频敏感聚合物的第三组分，和聚合物相容剂的第四组分。

公开(公告)号：EP1389068A4

公开(公告)日：2007-03-07

申请号：EP02728809

申请日：2002-04-17

Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA

Inventor： SMITH SIDNEY T ,  ROSENBAUM LARRY ,  NEBGEN GREGG ,  HURST WILLIAM S ,  HOERLE WILLIAM S ,  SADIK ADEL M ,  SKELNIK MELISSA J ,  GIOVANETTO STEVEN H ,  BUCHANAN BRADLEY

IPC: B65D30/02 ,  A61J1/00 ,  A61J1/05 ,  A61J1/10 ,  B32B1/08 ,  B32B27/08 ,  B32B27/30 ,  B65D65/40 ,  A61B19/00

CPC classification number: B32B27/30 ,  A61J1/10 ,  A61M2207/00 ,  B32B1/08 ,  Y10S128/24 ,  Y10S128/912 ,  Y10S206/828 ,  Y10S604/905 ,  Y10T428/1334 ,  Y10T428/1341 ,  Y10T428/2495 ,  Y10T428/269 ,  Y10T428/31757 ,  Y10T428/31909 ,  Y10T428/31913 ,  Y10T428/31935

公开(公告)号：AT537964T

公开(公告)日：2012-01-15

申请号：AT08755239

申请日：2008-05-09

Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA

Inventor： DING YUANPANG S ,  LING MICHAEL T ,  CHANG MOH-CHING O ,  VALLEE JEAN-MICHEL ,  NEBGEN GREGG

IPC: B32B1/08 ,  B32B15/08

公开(公告)号：DE69827762T2

公开(公告)日：2006-02-09

申请号：DE69827762

申请日：1998-09-18

Applicant: BAXTER INT

Inventor： SMITH T ,  ROSENBAUM A ,  GIOVANETTO STEVEN ,  BUCHANAN BRADLEY ,  DING SAMUEL ,  FAN C ,  NEBGEN GREGG

IPC: A61J1/10 ,  A61J1/00 ,  B32B27/08 ,  B32B27/28

公开(公告)号：CA2195628C

公开(公告)日：2005-04-19

申请号：CA2195628

申请日：1996-04-30

Applicant: BAXTER INT

Inventor： ROSENBAUM LARRY A ,  GIOVANETTO STEVEN ,  SMITH SIDNEY T ,  BACEHOWSKI DAVID V ,  NEBGEN GREGG ,  KALYANKAR VARSHA

IPC: B32B27/28 ,  B32B27/08 ,  B32B27/30 ,  B32B27/32 ,  C08L23/08 ,  C08L23/10 ,  C08L25/04 ,  C08L53/00 ,  C08L53/02 ,  C08L77/00

Abstract: A multiple layer structure comprising a skin layer, a barrier layer, a radio frequency susceptible layer having a first polyolefin in an amount within a range of 30-60 % by weight, a second polyolefin in an amount within the range of 25-50 % by weight, a radio frequency susceptible polymer in an amount within the range of 3-40 % by weight, a styrene and hydrocarbon block copolymer in an amount within the range of 5-40 % by weight of the sealant layer.