公开(公告)号：DE69527923T2

公开(公告)日：2003-04-24

申请号：DE69527923

申请日：1995-05-25

Applicant: BAXTER INT

Inventor： MARTIS LEO ,  HENDERSON W

IPC: A61K9/08 ,  A61K31/19 ,  A61K31/194 ,  A61K31/70 ,  A61K31/7004 ,  A61K33/00 ,  A61K33/10 ,  A61K33/14 ,  A61M1/28 ,  A61P7/08 ,  A61P13/12 ,  A61M1/16

Abstract: A peritoneal dialysis solution that is biochemically balanced to correct metabolic acidosis associated with chronic renal failure in a more physiological manner. The peritoneal dialysis solution has a physiological pH, e.g. pH of 70 to 74 and contains bicarbonate at a concentration that is found in normal blood. Additionally, the solution contains carbon dioxide at a partial pressure that is similar to partial pressure of carbon dioxide found in normal blood. The peritoneal dialysis solution also contains a weak acid with a pKa of less than 5.0.

公开(公告)号：DE69330221T2

公开(公告)日：2002-04-18

申请号：DE69330221

申请日：1993-01-08

Applicant: BAXTER INT

Inventor： OFSTHUN J ,  HENDERSON W ,  BROWN I ,  PAULEY G

IPC: A61M1/18 ,  B01D61/14 ,  B01D61/18 ,  B01D61/24 ,  B01D63/02 ,  B01D69/02 ,  B01D69/08 ,  B01D71/68 ,  C12M1/12 ,  C12M3/06 ,  B01D63/08

Abstract: The invention employs dual-skinned membranes useful as one way or rectifying membranes which reduce back filtration of solute molecules in dialysis and which improve nutrient supply and product recovery in membrane bioreactors. The membranes are dual-skinned polymeric materials preferably in the form of hollow fibers. The membranes have sieving coefficient characteristics different for flow of liquids in one direction from that in the opposite direction. Improved dialysis devices are formed by using bundles of the hollow fiber membranes as a dialysis means having rectifying properties. Improved bioreactors are formed by using bundles of hollow fiber as a growth vessel having rectifying properties.

公开(公告)号：DE69527923D1

公开(公告)日：2002-10-02

申请号：DE69527923

申请日：1995-05-25

Applicant: BAXTER INT

Inventor： MARTIS LEO ,  HENDERSON W

IPC: A61K9/08 ,  A61K31/19 ,  A61K31/194 ,  A61K31/70 ,  A61K31/7004 ,  A61K33/00 ,  A61K33/10 ,  A61K33/14 ,  A61M1/28 ,  A61P7/08 ,  A61P13/12 ,  A61M1/16

Abstract: A peritoneal dialysis solution that is biochemically balanced to correct metabolic acidosis associated with chronic renal failure in a more physiological manner. The peritoneal dialysis solution has a physiological pH, e.g. pH of 70 to 74 and contains bicarbonate at a concentration that is found in normal blood. Additionally, the solution contains carbon dioxide at a partial pressure that is similar to partial pressure of carbon dioxide found in normal blood. The peritoneal dialysis solution also contains a weak acid with a pKa of less than 5.0.

公开(公告)号：DE69330221D1

公开(公告)日：2001-06-21

申请号：DE69330221

申请日：1993-01-08

Applicant: BAXTER INT

Inventor： OFSTHUN J ,  HENDERSON W ,  BROWN I ,  PAULEY G

IPC: A61M1/18 ,  B01D61/14 ,  B01D61/18 ,  B01D61/24 ,  B01D63/02 ,  B01D69/02 ,  B01D69/08 ,  B01D71/68 ,  C12M1/12 ,  C12M3/06 ,  B01D63/08

Abstract: The invention employs dual-skinned membranes useful as one way or rectifying membranes which reduce back filtration of solute molecules in dialysis and which improve nutrient supply and product recovery in membrane bioreactors. The membranes are dual-skinned polymeric materials preferably in the form of hollow fibers. The membranes have sieving coefficient characteristics different for flow of liquids in one direction from that in the opposite direction. Improved dialysis devices are formed by using bundles of the hollow fiber membranes as a dialysis means having rectifying properties. Improved bioreactors are formed by using bundles of hollow fiber as a growth vessel having rectifying properties.