公开(公告)号：AT386512T

公开(公告)日：2008-03-15

申请号：AT02736532

申请日：2002-03-28

Applicant: BAXTER INT

Inventor： DOTY MARK ,  REBBECK CHRISTINE ,  KIPP JAMES ,  RAGHAVAN NEERVALUR

IPC: A61K31/343 ,  C07D307/80 ,  A61K9/00 ,  A61K9/08 ,  A61K47/02 ,  A61K47/10 ,  A61K47/18 ,  A61K47/26 ,  A61K47/34 ,  A61K47/36 ,  A61P9/06

公开(公告)号：AT450250T

公开(公告)日：2009-12-15

申请号：AT02773797

申请日：2002-10-18

Applicant: BAXTER INT

Inventor： KIPP JAMES ,  DOTY MARK ,  REBBECK CHRISTINE ,  BRYNJELSEN SEAN ,  KONKEL JAMIE

IPC: A61K9/10 ,  A61K8/02 ,  A61K8/04 ,  A61K8/06 ,  A61K8/34 ,  A61K8/35 ,  A61K8/36 ,  A61K8/365 ,  A61K8/37 ,  A61K8/39 ,  A61K8/40 ,  A61K8/41 ,  A61K8/44 ,  A61K8/46 ,  A61K8/60 ,  A61K8/64 ,  A61K8/73 ,  A61K8/86 ,  A61K8/89 ,  A61K8/891 ,  A61K9/107 ,  A61K9/14 ,  A61K31/12 ,  A61K31/4985 ,  A61K31/58 ,  A61K47/02 ,  A61K47/06 ,  A61K47/10 ,  A61K47/12 ,  A61K47/14 ,  A61K47/16 ,  A61K47/18 ,  A61K47/20 ,  A61K47/26 ,  A61K47/32 ,  A61K47/34 ,  A61K47/36 ,  A61K47/38 ,  A61K47/42 ,  A61K47/44 ,  A61K47/46 ,  A61Q19/00

Abstract: The present invention discloses a composition of a stable suspension of a poorly water soluble pharmaceutical agent or cosmetic in the form of particles of the pharmaceutical agent or cosmetic suspended in a frozen aqueous matrix and method for its preparation. The composition is stable for a prolonged period of time, preferably six months or longer and is suitable for parenteral, oral, or non-oral routes such as pulmonary (inhalation), ophthalmic, or topical administration.