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1.发明申请
公开(公告)号：WO2005030273A3
公开(公告)日：2005-06-09
申请号：PCT/US2004031107
申请日：2004-09-22
Applicant: BAXTER INT , RODRIGUEZ ALFREDO , RABINOW BARRETT E , DOTY MARK , KONKEL JAMIE
Inventor： RODRIGUEZ ALFREDO , RABINOW BARRETT E , DOTY MARK , KONKEL JAMIE
CPC classification number: B65B55/02 , A61L2/0011 , A61L2/0023 , A61L2/02 , A61L2/04
Abstract: The present invention provides a process for sterilizing a system, preferably a pharmaceutical preparation such as a dispersion of small particles or droplets of a pharmaceutically active compound using high pressure terminal sterilization techniques and products therefrom.
Abstract translation: 本发明提供了一种使用高压终端灭菌技术及其产品对系统，优选药物制剂如药物活性化合物的小颗粒或液滴分散体进行灭菌的方法。
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公开(公告)号：BRPI0414321A
公开(公告)日：2006-11-07
申请号：BRPI0414321
申请日：2004-09-22
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor： RODRIGUEZ ALFREDO , RABINOW BARRETT E , DOTY MARK J , KONKEL JAMIE
Abstract: The present invention provides a process for sterilizing a system, preferably a pharmaceutical preparation such as a dispersion of small particles or droplets of a pharmaceutically active compound using high pressure terminal sterilization techniques and products therefrom.
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3.发明专利
公开(公告)号：CA2539494C
公开(公告)日：2011-12-06
申请号：CA2539494
申请日：2004-09-22
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor： RODRIGUEZ ALFREDO , RABINOW BARRETT E , DOTY MARK , KONKEL JAMIE
Abstract: The present invention provides a process for sterilizing a system, preferably a pharmaceutical preparation such as a dispersion of small particles or droplets of a pharmaceutically active compound using high pressure terminal sterilization techniques and products therefrom.
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公开(公告)号：AT450250T
公开(公告)日：2009-12-15
申请号：AT02773797
申请日：2002-10-18
Applicant: BAXTER INT
Inventor： KIPP JAMES , DOTY MARK , REBBECK CHRISTINE , BRYNJELSEN SEAN , KONKEL JAMIE
IPC: A61K9/10 , A61K8/02 , A61K8/04 , A61K8/06 , A61K8/34 , A61K8/35 , A61K8/36 , A61K8/365 , A61K8/37 , A61K8/39 , A61K8/40 , A61K8/41 , A61K8/44 , A61K8/46 , A61K8/60 , A61K8/64 , A61K8/73 , A61K8/86 , A61K8/89 , A61K8/891 , A61K9/107 , A61K9/14 , A61K31/12 , A61K31/4985 , A61K31/58 , A61K47/02 , A61K47/06 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/16 , A61K47/18 , A61K47/20 , A61K47/26 , A61K47/32 , A61K47/34 , A61K47/36 , A61K47/38 , A61K47/42 , A61K47/44 , A61K47/46 , A61Q19/00
Abstract: The present invention discloses a composition of a stable suspension of a poorly water soluble pharmaceutical agent or cosmetic in the form of particles of the pharmaceutical agent or cosmetic suspended in a frozen aqueous matrix and method for its preparation. The composition is stable for a prolonged period of time, preferably six months or longer and is suitable for parenteral, oral, or non-oral routes such as pulmonary (inhalation), ophthalmic, or topical administration.
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5.发明专利
公开(公告)号：CA2539494A1
公开(公告)日：2005-04-07
申请号：CA2539494
申请日：2004-09-22
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor： RODRIGUEZ ALFREDO , RABINOW BARRETT E , DOTY MARK , KONKEL JAMIE
Abstract: The present invention provides a process for sterilizing a system, preferably a pharmaceutical preparation such as a dispersion of small particles or droplets of a pharmaceutically active compound using high pressure terminal sterilization techniques and products therefrom.
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Patent Agency Ranking
公开(公告)号：BRPI0414321B1
公开(公告)日：2015-05-26
申请号：BRPI0414321
申请日：2004-09-22
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor： RODRIGUEZ ALFREDO , RABINOW BARRETT E , DOTY MARK J , KONKEL JAMIE
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公开(公告)号：ES2394208T3
公开(公告)日：2013-01-23
申请号：ES04784813
申请日：2004-09-22
Applicant: BAXTER INTERNAT INC A DELAWARE CORP , BAXTER INT , BAXTER HEALTHCARE SA
Inventor： RODRIGUEZ ALFREDO , RABINOW BARRETT , DOTY MARK , KONKEL JAMIE
Abstract: Método para esterilizar un sistema de dispersión dinámico que comprende los pasos de presurizar elsistema por encima de 0,25 MPa para aumentar la temperatura del sistema por encima de 100ºC duranteun período suficiente para obtener un sistema estéril, donde el sistema de dispersión tiene una micro- onano-dispersión de partículas finas o gotitas y las partículas finas o gotitas presentan un estado estable yun estado inestable; y eliminar la presión sobre el sistema antes de que las partículas finas o las gotitas delmismo alcancen el estado inestable, caracterizado porque las partículas o gotitas comprenden uncompuesto terapéuticamente activo y un excipiente que se asocia al compuesto terapéuticamente activo ycomprendiendo un agente tensioactivo
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8.发明专利
公开(公告)号：AU2004275764B2
公开(公告)日：2010-01-14
申请号：AU2004275764
申请日：2004-09-22
Applicant: BAXTER HEALTHCARE SA , BAXTER INT
Inventor： RABINOW BARRETT E , KONKEL JAMIE , RODRIGUEZ ALFREDO , DOTY MARK
Abstract: The present invention provides a process for sterilizing a system, preferably a pharmaceutical preparation such as a dispersion of small particles or droplets of a pharmaceutically active compound using high pressure terminal sterilization techniques and products therefrom.
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9.发明专利
公开(公告)号：DK1663321T3
公开(公告)日：2012-11-19
申请号：DK04784813
申请日：2004-09-22
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor： RODRIGUEZ ALFREDO , RABINOW BARRETT E , DOTY MARK , KONKEL JAMIE
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10.发明专利
公开(公告)号：PT1663321E
公开(公告)日：2012-11-15
申请号：PT04784813
申请日：2004-09-22
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor： RODRIGUEZ ALFREDO , RABINOW BARRETT E , DOTY MARK , KONKEL JAMIE
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