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公开(公告)号：ES2125630T3
公开(公告)日：1999-03-01
申请号：ES95924737
申请日：1995-06-29
Applicant: BAXTER INT
Inventor： GELLER ROBIN LEE , BRAUKER JAMES H , JOHNSTON WILLIAM D , LEVON STEVEN A , MARYANOV DAVID A
Abstract: An implantable device for the prevention or treatment of cancer comprising an implantable chamber containing tumor cells, or somatic cells engineered to express at least one antigen corresponding to antigen of a patient's tumor; the chamber having a porous wall to provide, in use, a porous boundary between the patient's immune cells and the contained cells; the porosity of the boundary being sufficient to permit subcellular antigenic material to pass through the boundary, while preventing the contained cells and patient immune cells from passing through the boundary.
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公开(公告)号：AU699405B2
公开(公告)日：1998-12-03
申请号：AU2912895
申请日：1995-06-29
Applicant: BAXTER INT
Inventor： GELLER ROBIN LEE , BRAUKER JAMES H , JOHNSTON WILLIAM D , LEVON STEVEN A , MARYANOV DAVID A
Abstract: An implantable device for the prevention or treatment of cancer comprising an implantable chamber containing tumor cells, or somatic cells engineered to express at least one antigen corresponding to antigen of a patient's tumor; the chamber having a porous wall to provide, in use, a porous boundary between the patient's immune cells and the contained cells; the porosity of the boundary being sufficient to permit subcellular antigenic material to pass through the boundary, while preventing the contained cells and patient immune cells from passing through the boundary.
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公开(公告)号：NO970054A
公开(公告)日：1997-03-10
申请号：NO970054
申请日：1997-01-07
Applicant: BAXTER INT
Inventor： GELLER ROBIN LEE , BRAUKER JAMES H , JOHNSTON WILLIAM D , LEVON STEVEN A , MARYANOV DAVID A
IPC: A61K9/00 , A61K35/12 , A61K35/13 , A61K38/00 , A61K38/19 , A61K39/00 , A61P35/00 , C12N5/08 , A61K39/385 , A61K39/39
CPC classification number: A61K9/0024 , A61K35/13 , A61K38/19 , A61K39/0011 , A61K2039/5152 , A61K2300/00
Abstract: An implantable device for the prevention or treatment of cancer comprising an implantable chamber containing tumor cells, or somatic cells engineered to express at least one antigen corresponding to antigen of a patient's tumor; the chamber having a porous wall to provide, in use, a porous boundary between the patient's immune cells and the contained cells; the porosity of the boundary being sufficient to permit subcellular antigenic material to pass through the boundary, while preventing the contained cells and patient immune cells from passing through the boundary.
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公开(公告)号：CA2194555A1
公开(公告)日：1996-01-25
申请号：CA2194555
申请日：1995-06-29
Applicant: BAXTER INT
Inventor： MARYANOV DAVID A , BRAUKER JAMES H , JOHNSTON WILLIAM D , GELLER ROBIN LEE , LEVON STEVEN A
IPC: A61K9/00 , A61K35/12 , A61K35/13 , A61K38/00 , A61K38/19 , A61K39/00 , A61P35/00 , A61M37/00 , A61K38/17
Abstract: An implantable device for the prevention or treatment of cancer comprising a n implantable chamber containing tumor cells, or somatic cells engineered to express at least one antigen corresponding to antigen of a patient's tumor, the chamber having a porous wall to provide, in use, a porous boundary between the patient's immune cells and the contain ed cells; the porosity of the boundary being sufficient to permit subcellular antigenic material to pass through the boundary, while preventin g the contained cells and patient immune cells from passing through the boundary.
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公开(公告)号：CA2194555C
公开(公告)日：2002-01-29
申请号：CA2194555
申请日：1995-06-29
Applicant: BAXTER INT
Inventor： GELLER ROBIN LEE , BRAUKER JAMES H , JOHNSTON WILLIAM D , LEVON STEVEN A , MARYANOV DAVID A
IPC: A61K9/00 , A61K35/12 , A61K35/13 , A61K38/00 , A61K38/19 , A61K39/00 , A61P35/00 , A61M37/00 , A61K38/17
Abstract: An implantable device for the prevention or treatment of cancer comprising a n implantable chamber containing tumor cells, or somatic cells engineered to express at least one antigen corresponding to antigen of a patient's tumor, the chamber having a porous wall to provide, in use, a porous boundary between the patient's immune cells and the contain ed cells; the porosity of the boundary being sufficient to permit subcellular antigenic material to pass through the boundary, while preventin g the contained cells and patient immune cells from passing through the boundary.
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Patent Agency Ranking
公开(公告)号：DK0769932T3
公开(公告)日：1999-06-23
申请号：DK95924737
申请日：1995-06-29
Applicant: BAXTER INT
Inventor： BRAUKER JAMES H , GELLER ROBIN LEE , JOHNSTON WILLIAM D , LEVON STEVEN A , MARYANOV DAVID A
Abstract: An implantable device for the prevention or treatment of cancer comprising an implantable chamber containing tumor cells, or somatic cells engineered to express at least one antigen corresponding to antigen of a patient's tumor; the chamber having a porous wall to provide, in use, a porous boundary between the patient's immune cells and the contained cells; the porosity of the boundary being sufficient to permit subcellular antigenic material to pass through the boundary, while preventing the contained cells and patient immune cells from passing through the boundary.
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公开(公告)号：AU2912895A
公开(公告)日：1996-02-09
申请号：AU2912895
申请日：1995-06-29
Applicant: BAXTER INT
Inventor： GELLER ROBIN LEE , BRAUKER JAMES H , JOHNSTON WILLIAM D , LEVON STEVEN A , MARYANOV DAVID A
Abstract: An implantable device for the prevention or treatment of cancer comprising an implantable chamber containing tumor cells, or somatic cells engineered to express at least one antigen corresponding to antigen of a patient's tumor; the chamber having a porous wall to provide, in use, a porous boundary between the patient's immune cells and the contained cells; the porosity of the boundary being sufficient to permit subcellular antigenic material to pass through the boundary, while preventing the contained cells and patient immune cells from passing through the boundary.
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公开(公告)号：AT172099T
公开(公告)日：1998-10-15
申请号：AT95924737
申请日：1995-06-29
Applicant: BAXTER INT
Inventor： GELLER ROBIN LEE , BRAUKER JAMES H , JOHNSTON WILLIAM D , LEVON STEVEN A , MARYANOV DAVID A
Abstract: An implantable device for the prevention or treatment of cancer comprising an implantable chamber containing tumor cells, or somatic cells engineered to express at least one antigen corresponding to antigen of a patient's tumor; the chamber having a porous wall to provide, in use, a porous boundary between the patient's immune cells and the contained cells; the porosity of the boundary being sufficient to permit subcellular antigenic material to pass through the boundary, while preventing the contained cells and patient immune cells from passing through the boundary.
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公开(公告)号：MX9700148A
公开(公告)日：1998-01-31
申请号：MX9700148
申请日：1995-06-29
Applicant: BAXTER INT
Inventor： GELLER ROBIN LEE , BRAUKER JAMES H , JOHNSTON WILLIAM D , LEVON STEVEN A , MARYANOV DAVID A
Abstract: Un dispositivo implantable para la prevencion o tratamiento del cáncer, comprende una cámara implantable que contiene células de tumor, o células somáticas preparadas por ingeniería para expresar al menos un antígeno que corresponde al antígeno de un tumor del paciente, la cámara tiene una pared porosa para suministrar en uso, una frontera porosa entre las células inmunes del paciente y las células contenidas; la porosidad de la frontera siendo suficiente para permitir que el material antigénico subcelular pase a través de la frontera, mientras se evita que las células contenidas y las células inmunes del paciente pasen a través de la frontera.
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公开(公告)号：NO970054L
公开(公告)日：1997-03-10
申请号：NO970054
申请日：1997-01-07
Applicant: BAXTER INT
Inventor： GELLER ROBIN LEE , BRAUKER JAMES H , JOHNSTON WILLIAM D , LEVON STEVEN A , MARYANOV DAVID A
IPC: A61K9/00 , A61K35/12 , A61K35/13 , A61K38/00 , A61K38/19 , A61K39/00 , A61P35/00 , C12N5/08 , A61K39/385 , A61K39/39
Abstract: An implantable device for the prevention or treatment of cancer comprising an implantable chamber containing tumor cells, or somatic cells engineered to express at least one antigen corresponding to antigen of a patient's tumor; the chamber having a porous wall to provide, in use, a porous boundary between the patient's immune cells and the contained cells; the porosity of the boundary being sufficient to permit subcellular antigenic material to pass through the boundary, while preventing the contained cells and patient immune cells from passing through the boundary.
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