4.
    发明专利
    未知

    公开(公告)号:DK0769932T3

    公开(公告)日:1999-06-23

    申请号:DK95924737

    申请日:1995-06-29

    Applicant: BAXTER INT

    Abstract: An implantable device for the prevention or treatment of cancer comprising an implantable chamber containing tumor cells, or somatic cells engineered to express at least one antigen corresponding to antigen of a patient's tumor; the chamber having a porous wall to provide, in use, a porous boundary between the patient's immune cells and the contained cells; the porosity of the boundary being sufficient to permit subcellular antigenic material to pass through the boundary, while preventing the contained cells and patient immune cells from passing through the boundary.

    5.
    发明专利
    未知

    公开(公告)号:DK0579787T3

    公开(公告)日:1997-07-07

    申请号:DK92921233

    申请日:1992-09-25

    Applicant: BAXTER INT

    Abstract: The coating of a RF active material on a non-RF active substrate material of typical thickness for packaging purposes, can generate sufficient thermal energy to effect strong bonding of the substrate materials. The RF active material may be-deposited on less than the entire inner surface area of the substrate material, preferably, at or near the portion of the substrate surface which represents the heat seal interface. In this manner of application, additional coating or printing of other substances on the substrate surface can be achieved without hampering the heat sealing process. Flexible medical containers capable of containing a product which is maintained and removed under sterile conditions, can be constructed on commercial production machines from these coated non-RF active substrate materials.

    7.
    发明专利
    未知

    公开(公告)号:DE3782745D1

    公开(公告)日:1993-01-07

    申请号:DE3782745

    申请日:1987-02-05

    Applicant: BAXTER INT

    Abstract: Flexible container has a body section of plastics film having at least two layers, with one, inner, layer formed of a selected, crosslinkable material free of leachable plasticiser and a second outer layer formed of material which is substantially non crosslinkable and has a higher meltinq point than the first layer. The body section is irradiated to achieve a selected level of crosslinking and heat resistance in the first layer. The container is sterilised before use. Pref. inner layer is of poly(ethylene vinyl acetate) containing 10 to 35 wt.% vinylacetate units and the outler layer is of polyethylene, polypropylene or copolymers, blends, or alloys.

    9.
    发明专利
    未知

    公开(公告)号:AT208169T

    公开(公告)日:2001-11-15

    申请号:AT93908495

    申请日:1993-03-25

    Applicant: BAXTER INT

    Abstract: Implant assemblies (10) and methodologies provide immuno-protection for implanted allografts, xenografts, and isografts. The assemblies and methodologies establish an improved boundary between the host and the implanted cells (12). The boundary has a pore size, an ultimate strength, and a metabolic transit value that assures the survival of the cells (12) during the critical ischemic period and afterward. The boundary allows the fabrication and clinical use of implant assemblies and methodologies that can carry enough cells (12) to be of therapeutic value to the host, yet occupy a relatively small, compact area within the host.

    10.
    发明专利
    未知

    公开(公告)号:ES2125630T3

    公开(公告)日:1999-03-01

    申请号:ES95924737

    申请日:1995-06-29

    Applicant: BAXTER INT

    Abstract: An implantable device for the prevention or treatment of cancer comprising an implantable chamber containing tumor cells, or somatic cells engineered to express at least one antigen corresponding to antigen of a patient's tumor; the chamber having a porous wall to provide, in use, a porous boundary between the patient's immune cells and the contained cells; the porosity of the boundary being sufficient to permit subcellular antigenic material to pass through the boundary, while preventing the contained cells and patient immune cells from passing through the boundary.

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