Abstract:
The coating of a RF active material on a non-RF active substrate material of typical thickness for packaging purposes, can generate sufficient thermal energy to effect strong bonding of the substrate materials. The RF active material may be-deposited on less than the entire inner surface area of the substrate material, preferably, at or near the portion of the substrate surface which represents the heat seal interface. In this manner of application, additional coating or printing of other substances on the substrate surface can be achieved without hampering the heat sealing process. Flexible medical containers capable of containing a product which is maintained and removed under sterile conditions, can be constructed on commercial production machines from these coated non-RF active substrate materials.
Abstract:
An implantable device for the prevention or treatment of cancer comprising a n implantable chamber containing tumor cells, or somatic cells engineered to express at least one antigen corresponding to antigen of a patient's tumor, the chamber having a porous wall to provide, in use, a porous boundary between the patient's immune cells and the contain ed cells; the porosity of the boundary being sufficient to permit subcellular antigenic material to pass through the boundary, while preventin g the contained cells and patient immune cells from passing through the boundary.
Abstract:
An implantable device for the prevention or treatment of cancer comprising an implantable chamber containing tumor cells, or somatic cells engineered to express at least one antigen corresponding to antigen of a patient's tumor; the chamber having a porous wall to provide, in use, a porous boundary between the patient's immune cells and the contained cells; the porosity of the boundary being sufficient to permit subcellular antigenic material to pass through the boundary, while preventing the contained cells and patient immune cells from passing through the boundary.
Abstract:
The coating of a RF active material on a non-RF active substrate material of typical thickness for packaging purposes, can generate sufficient thermal energy to effect strong bonding of the substrate materials. The RF active material may be-deposited on less than the entire inner surface area of the substrate material, preferably, at or near the portion of the substrate surface which represents the heat seal interface. In this manner of application, additional coating or printing of other substances on the substrate surface can be achieved without hampering the heat sealing process. Flexible medical containers capable of containing a product which is maintained and removed under sterile conditions, can be constructed on commercial production machines from these coated non-RF active substrate materials.
Abstract:
An implantable device for the prevention or treatment of cancer comprising an implantable chamber containing tumor cells, or somatic cells engineered to express at least one antigen corresponding to antigen of a patient's tumor; the chamber having a porous wall to provide, in use, a porous boundary between the patient's immune cells and the contained cells; the porosity of the boundary being sufficient to permit subcellular antigenic material to pass through the boundary, while preventing the contained cells and patient immune cells from passing through the boundary.
Abstract:
Flexible container has a body section of plastics film having at least two layers, with one, inner, layer formed of a selected, crosslinkable material free of leachable plasticiser and a second outer layer formed of material which is substantially non crosslinkable and has a higher meltinq point than the first layer. The body section is irradiated to achieve a selected level of crosslinking and heat resistance in the first layer. The container is sterilised before use. Pref. inner layer is of poly(ethylene vinyl acetate) containing 10 to 35 wt.% vinylacetate units and the outler layer is of polyethylene, polypropylene or copolymers, blends, or alloys.
Abstract:
A film laminate for flexible containers capable of containing a product to be maintained and accessed under sterile conditions. The laminate having an outside layer of linear low density polyethylene, a core layer of nylon, an inside layer of linear low density polyethylene and two layers of a polyurethane adhesive for bonding the layers.
Abstract:
Implant assemblies (10) and methodologies provide immuno-protection for implanted allografts, xenografts, and isografts. The assemblies and methodologies establish an improved boundary between the host and the implanted cells (12). The boundary has a pore size, an ultimate strength, and a metabolic transit value that assures the survival of the cells (12) during the critical ischemic period and afterward. The boundary allows the fabrication and clinical use of implant assemblies and methodologies that can carry enough cells (12) to be of therapeutic value to the host, yet occupy a relatively small, compact area within the host.
Abstract:
An implantable device for the prevention or treatment of cancer comprising an implantable chamber containing tumor cells, or somatic cells engineered to express at least one antigen corresponding to antigen of a patient's tumor; the chamber having a porous wall to provide, in use, a porous boundary between the patient's immune cells and the contained cells; the porosity of the boundary being sufficient to permit subcellular antigenic material to pass through the boundary, while preventing the contained cells and patient immune cells from passing through the boundary.