公开(公告)号：DE69130218T2

公开(公告)日：1999-05-12

申请号：DE69130218

申请日：1991-12-20

Applicant: BAXTER INT

Inventor： WOLF LUDWIG ,  FOLEY JOHN ,  BRATTEN WILLIAM

IPC: A61K35/14 ,  A61L2/00 ,  A61M1/36 ,  B01J19/12 ,  A61L2/08

公开(公告)号：DE69418296T2

公开(公告)日：1999-09-09

申请号：DE69418296

申请日：1994-07-06

Applicant: BAXTER INT

Inventor： WOLF LUDWIG ,  BRATTEN WILLIAM ,  FOLEY JOHN

IPC: B01J19/12 ,  A01N1/02 ,  A61L2/00 ,  A61L2/08 ,  A61M1/36 ,  A61M1/14 ,  B01J19/08

公开(公告)号：DE69117940D1

公开(公告)日：1996-04-18

申请号：DE69117940

申请日：1991-12-20

Applicant: BAXTER INT

Inventor： BISCHOF DANIEL ,  WOLF LUDWIG ,  FOLEY JOHN ,  BRATTEN WILLIAM

IPC: A61M1/36 ,  A61L2/00 ,  A61L2/08 ,  A61M1/34 ,  B01J19/12 ,  A61M37/00

Abstract: A system and method for treating a fluid carrying a biological contaminant to which a photoactive material has been bound include a treatment device that defines a flow passage with a gap. The system and method operate to establish a flow of fluid from the inlet end of the gap to the outlet end of the gap. The system and method expose the fluid, as it transits the gap, to a source of radiation that activates the photoactive material bound to the contaminant. The system and method also mix the fluid as it flows within the gap.

公开(公告)号：DE69130902T2

公开(公告)日：1999-09-30

申请号：DE69130902

申请日：1991-12-20

Applicant: BAXTER INT ,  QUADRA LOGIC TECH INC

Inventor： WOLF LUDWIG ,  FOLEY JOHN ,  BRATTEN WILLIAM ,  STONEFIELD MICHAEL ,  KUNZ GARY

IPC: A61L2/00 ,  A61L2/08 ,  A61L2/10 ,  A61M1/36 ,  B01J19/12

Abstract: A system and method for treating a fluid carrying a contaminant to which a photoactive material has been bound include a treatment device that defines a flow passage with a gap. The system and method operate to establish a flow of fluid from the inlet end of the gap to the outlet end of the gap. The system and method also channel the flow of fluid in the gap in succession through one or more flow paths. The system and method establish at least two discrete sources of radiation in the flow path at spaced apart locations along the direction of fluid flow. At least one of the radiation sources comprises a photodiode. The system and method further include a control for operating each discrete source of radiation at a selected wavelength within the prescribed range to activate the photoactive material bound to the contaminant. Upon activation, the material eradicates the contaminant. The system and method provide extracorporeal treatment of fluids like blood to quickly and effectively eradicate infection agents at relatively high flow rates.

公开(公告)号：DE69418296D1

公开(公告)日：1999-06-10

申请号：DE69418296

申请日：1994-07-06

Applicant: BAXTER INT

Inventor： WOLF LUDWIG ,  BRATTEN WILLIAM ,  FOLEY JOHN

IPC: B01J19/12 ,  A01N1/02 ,  A61L2/00 ,  A61L2/08 ,  A61M1/36 ,  A61M1/14 ,  B01J19/08

公开(公告)号：DE69130218D1

公开(公告)日：1998-10-22

申请号：DE69130218

申请日：1991-12-20

Applicant: BAXTER INT

Inventor： WOLF LUDWIG ,  FOLEY JOHN ,  BRATTEN WILLIAM

IPC: A61K35/14 ,  A61L2/00 ,  A61M1/36 ,  B01J19/12 ,  A61L2/08

公开(公告)号：DE69130902D1

公开(公告)日：1999-03-25

申请号：DE69130902

申请日：1991-12-20

Applicant: BAXTER INT ,  QUADRA LOGIC TECH INC

Inventor： WOLF LUDWIG ,  FOLEY JOHN ,  BRATTEN WILLIAM ,  STONEFIELD MICHAEL ,  KUNZ GARY

IPC: A61L2/00 ,  A61L2/08 ,  A61L2/10 ,  A61M1/36 ,  B01J19/12

Abstract: A system and method for treating a fluid carrying a contaminant to which a photoactive material has been bound include a treatment device that defines a flow passage with a gap. The system and method operate to establish a flow of fluid from the inlet end of the gap to the outlet end of the gap. The system and method also channel the flow of fluid in the gap in succession through one or more flow paths. The system and method establish at least two discrete sources of radiation in the flow path at spaced apart locations along the direction of fluid flow. At least one of the radiation sources comprises a photodiode. The system and method further include a control for operating each discrete source of radiation at a selected wavelength within the prescribed range to activate the photoactive material bound to the contaminant. Upon activation, the material eradicates the contaminant. The system and method provide extracorporeal treatment of fluids like blood to quickly and effectively eradicate infection agents at relatively high flow rates.

公开(公告)号：DE69117940T2

公开(公告)日：1996-11-21

申请号：DE69117940

申请日：1991-12-20

Applicant: BAXTER INT

Inventor： BISCHOF DANIEL ,  WOLF LUDWIG ,  FOLEY JOHN ,  BRATTEN WILLIAM

IPC: A61M1/36 ,  A61L2/00 ,  A61L2/08 ,  A61M1/34 ,  B01J19/12 ,  A61M37/00

Abstract: A system and method for treating a fluid carrying a biological contaminant to which a photoactive material has been bound include a treatment device that defines a flow passage with a gap. The system and method operate to establish a flow of fluid from the inlet end of the gap to the outlet end of the gap. The system and method expose the fluid, as it transits the gap, to a source of radiation that activates the photoactive material bound to the contaminant. The system and method also mix the fluid as it flows within the gap.