公开(公告)号：WO1996032130A1

公开(公告)日：1996-10-17

申请号：PCT/US1996004776

申请日：1996-04-08

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  BURHOP, Kenneth, E. ,  COLE, Daniel, J.

IPC: A61K38/16

CPC classification number: A61K38/42

Abstract: Cross-linked hemoglobin infusion following subarachnoid hemorrhage dramatically reduces the tissue area of hypoperfusion and reduces the extent of neuronal damage in the area of hypoperfusion. A therapeutically effective dose ranges from about 1000-5500 mg of body weight and may be administered up to 72 hours after the onset of hemorrhage.

Abstract translation: 蛛网膜下腔出血后交叉血红蛋白输注显着降低灌注不足的组织面积，并减少灌注不足区域神经元损伤的程度。 治疗有效剂量范围为约1000-5500mg体重，并且可以在出血发作后至多72小时施用。