公开(公告)号：WO1992019284A1

公开(公告)日：1992-11-12

申请号：PCT/US1992003422

申请日：1992-04-27

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  GRIMM, Daniel, J. ,  LEUENBERGER, Mark, S.

IPC: A61L02/12

CPC classification number: A61L2/10 ,  A61J1/10 ,  A61J1/1406 ,  A61J1/1462 ,  A61J1/1468 ,  A61J1/1487 ,  A61J2205/10 ,  A61J2205/20 ,  A61J2205/30 ,  A61L2/0011 ,  Y10T436/12

Abstract: A container (10) for irradiation comprises a flexible, flat collapsible wall (12, 13) defining a sealed chamber (36), the plastic material of the wall (12, 13) is substantially transparent to irradiation, typically ultraviolet radiation. Access ports (22, 24, 26) are provided for communicating through the wall (12, 13) to the chamber (36). A flap (32) is provided, integral with the wall (12, 13) and spaced from the chamber (36), and carries identifying indicia (38) including a typical bar code indicia (40), so that the wall (12, 13) may be at least substantially free of opaque indicia. Also, structure may be provided for detecting and indicating exposure of the container to irradiation, such as ultraviolet sensitive tape (50) adhering to the flap (32). Alignment holes (46) may be provided, typically in the flap (32), to facilitate orientation of the container (10) with apparatus for irradiation (51) and apparatus for bar code reading (72), making use of alignment pins (70) carried by such apparatus (51).

Abstract translation: 用于照射的容器（10）包括限定密封室（36）的柔性的，平坦的可折叠壁（12,13），所述壁（12,13）的塑料材料对照射（通常为紫外线辐射）基本上是透明的。 提供进入端口（22,24,26）用于通过壁（12,13）连通到室（36）。 提供了一个与所述壁（12,13）成一体并且与所述室（36）间隔开的折板（32），并且携带包括典型条形码标记（40）的识别标记（38），使得所述壁 13）可以至少基本上不含不透明标记。 而且，可以提供用于检测和指示容器照射的结构，例如粘附到翼片（32）上的紫外线敏感带（50）。 通常可以在翼片（32）中设置对准孔（46），以便利用用于照射的装置（51）和用于条形码读取装置（72）的容器（10）的取向，利用对准销（70 ）由该装置（51）承载。

公开(公告)号：EP0981388A1

公开(公告)日：2000-03-01

申请号：EP99908459.3

申请日：1999-02-25

Applicant: BAXTER INTERNATIONAL INC.(a Delaware corporation)

Inventor： GRIMM, Daniel, J.

IPC: A61M37/00

CPC classification number: A61M1/3672 ,  A61M1/3696

Abstract: An apheresis system (10) is disclosed which may include a separation chamber (20); a suspension flow path which communicates at one end with the separation chamber and includes a connector (16) at the other end for connecting to a source of cellular suspension; an anticoagulant flow path which communicates at one end with the suspension flow path and includes a connector (26) at the other end for connecting to an anticoagulant source (22); and a return flow path which communicates at one end with the separation chamber and communicates at the other end with a connector (18) for connection directly to the suspension source or to the suspension flow path for returning one or more suspension components to the source. The anticoagulant flow path includes a flow restriction, such as an internal flow restriction, which limits the free flow of anticoagulants into the suspension flow path while preferably not completely stopping the flow of anticoagulant. The restriction may take various forms, but the preferred construction comprises a tubing segment (49) of reduced inside diameter, providing resistance to the free flow of anticoagulant in the event of operator error or mechanical failure.