公开(公告)号：CA2619866A1

公开(公告)日：2007-03-22

申请号：CA2619866

申请日：2006-08-31

Applicant: BIO RAD LABORATORIES

Inventor： LATHAM MATTHEW

IPC: C25B9/00

Abstract: Slab gel electrophoresis cassettes constructed from two flat rectangular plates, with features that allow the plates to be joined parallel to and facing each other with a gap between them that is sealed at the sides and open at the top and bottom for access to upper and lower electrodes, respectively, are improved by two independent features. The first is the integration of an elastomeric gasket to the surface of one of the two plates to ensure a liquid-tight seal, while the second is the inclusion of edge engaging members that are mounted to one plate and engage an opposing edge of the other plate. The engaging members are manually engaged and released at will. In preferred constructions, the gasket is a strip that extends along the two sides and bottom of one of the plates, and each engaging member is pivotally and resiliently mounted to achieve a snap-type engagement.

公开(公告)号：AU2005314329A1

公开(公告)日：2006-06-15

申请号：AU2005314329

申请日：2005-12-01

Applicant: BIO RAD LABORATORIES ,  CALIPER LIFE SCIENCES INC

Inventor： KENNEDY COLIN ,  LATHAM MATTHEW ,  BORONKAY ALLEN

IPC: C12M3/00

Abstract: A priming unit for a microfluidics device contains a pressurization unit and pressure and temperature detectors as part of a feedback loop that controls the pressure applied by the pressurization unit and the time during which the pressure is applied. This control feature is particularly useful in controlling the exposure time of the microchannels to dyes in the priming liquids since certain dyes tend to adhere to the walls of the channels and produce non-uniform results.

公开(公告)号：CA2587689C

公开(公告)日：2014-07-08

申请号：CA2587689

申请日：2005-12-01

Applicant: BIO RAD LABORATORIES ,  CALIPER LIFE SCIENCES INC

Inventor： BORONKAY ALLEN ,  KENNEDY COLIN ,  LATHAM MATTHEW

IPC: G01N1/00 ,  G01N1/10 ,  G01N27/00 ,  G01N35/10

Abstract: A priming unit (31) for a microfluidics device (11) containing a pressurization unit (35) and pressure (46) and temperature detectors as part of a feedback loyg (55) that controls the pressure applied by the pressurization unit (35) an the time during which the pressure is applied. This control feature is particularly useful in controlling the exposure time of the microchannels (15) to dyes in the priming liquids since certain dyes tend to adhere to the walls of the channels and produce non-uniform results.

公开(公告)号：SG173721A1

公开(公告)日：2011-09-29

申请号：SG2011059045

申请日：2010-02-22

Applicant: BIO RAD LABORATORIES

Inventor： LATHAM MATTHEW

IPC: C25B9/19

Abstract: An electroblotting cassette is formed in three separable parts—an upper plate, a lower plate, and a base that receives both plates, with electrodes mounted on both the upper and lower plates. The cassette accommodates transfer stacks of different thicknesses by its inclusion of a set of raised areas, known as “lands,” on the floor of the base and a set of inverse lands on the underside of the lower electrode plate, the two sets being spatially arranged to either abut each other or be offset from each other, depending on the orientation of the lower plate, thereby allowing the user a choice between two heights of the lower plate within the base and hence two thicknesses of transfer stacks. Other arrangements include those with more than one set of lands on one or both parts to allow for three or more thickness selections, or depressions in place of lands. Finger-operated latches secure the upper plate to the base.

公开(公告)号：WO2007032951A3

公开(公告)日：2007-11-08

申请号：PCT/US2006034473

申请日：2006-08-31

Applicant: BIO RAD LABORATORIES ,  LATHAM MATTHEW

Inventor： LATHAM MATTHEW

IPC: C25B9/00

CPC classification number: G01N27/44704

Abstract: Slab gel electrophoresis cassettes constructed from two flat rectangular plates, with features that allow the plates to be joined parallel to and facing each other with a gap between them that is sealed at the sides and open at the top and bottom for access to upper and lower electrodes, respectively, are improved by two independent features. The first is the integration of an elastomeric gasket to the surface of one of the two plates to ensure a liquid-tight seal, while the second is the inclusion of edge engaging members that are mounted to one plate and engage an opposing edge of the other plate. The engaging members are manually engaged and released at will. In preferred constructions, the gasket is a strip that extends along the two sides and bottom of one of the plates, and each engaging member is pivotally and resiliently mounted to achieve a snap-type engagement.

Abstract translation: 由两块扁平矩形板构成的平板凝胶电泳盒，具有允许板彼此平行且面向彼此连接的特征，其间具有间隙，所述间隙在侧面密封并且在顶部和底部开口用于进入上部和下部 电极分别通过两个独立的特征得到改进。 第一种是将弹性垫圈集成到两块板之一的表面上以确保液密密封，而第二种是包括安装到一块板上并接合另一块板的相对边缘的边缘接合构件 盘子。 接合件可以随意手动接合和释放。 在优选的构造中，垫圈是沿一个板的两侧和底部延伸的条，并且每个接合构件枢转且弹性地安装以实现卡扣式接合。

公开(公告)号：SG192792A1

公开(公告)日：2013-09-30

申请号：SG2013062146

申请日：2012-02-24

Applicant: BIO RAD LABORATORIES

Inventor： PANATTONI CORY ,  LATHAM MATTHEW ,  KIMMEL KARA ,  WALKER JOHN

Abstract: Slab gel cassettes for use in electrophoretic analyses of biologically-derived mixtures are equipped with features that prevent the plastic walls of the cassettes from bowing outward when gels retained within the cassettes swell, as gels typically do during casting, storage, or both. In certain embodiments, these features are incorporated into, or mate with, the comb-shaped inserts that form the sample wells as the gels are being cast. In other embodiments, these features are complementary features incorporated into both the comb and the cassette.

公开(公告)号：CA2782021A1

公开(公告)日：2011-06-16

申请号：CA2782021

申请日：2010-12-09

Applicant: BIO RAD LABORATORIES

Inventor： LATHAM MATTHEW

IPC: B01D57/02 ,  G01N33/559

Abstract: An electrotransfer cassette is formed in two parts that are releasably joined by a manually operated locking mechanism. The joined parts have electrical contact areas extending from the electrodes in the two parts of the cassette, the contact areas being exposed on an outer edge of the resulting cassette to form electrical connections to a power supply upon the simple insertion of the cassette into an instrument.

公开(公告)号：CA2752923A1

公开(公告)日：2010-08-26

申请号：CA2752923

申请日：2010-02-22

Applicant: BIO RAD LABORATORIES

Inventor： LATHAM MATTHEW

IPC: C07K1/26 ,  C25B9/19

Abstract: An electroblotting comprising an upper plate, a lower plate, and a base that receives both plates, with electrodes mounted on both the upper and lower plates. The cassette accommodates transfer stacks of different thicknesses by its inclusion of a set of raised areas, known as "lands", on the floor of the base and a set of inverse lands on the underside of the lower electrode plate, the two sets being spatially arranged to either abut each other or be offset from each other, depending on the orientation of the lower plate, thereby allowing the user a choice between two heights of the lower plate within the base and hence two thicknesses of transfer stacks. More than one set of lands on one or both parts allows for three or more thickness selections, or depressions in place of lands. Finger-operated latches secure the upper plate to the base.

公开(公告)号：AU2012222167B2

公开(公告)日：2015-07-30

申请号：AU2012222167

申请日：2012-02-24

Applicant: BIO RAD LABORATORIES

Inventor： PANATTONI CORY ,  LATHAM MATTHEW ,  KIMMEL KARA ,  WALKER JOHN

IPC: G01N27/26

Abstract: Slab gel cassettes for use in electrophoretic analyses of biologically-derived mixtures are equipped with features that prevent the plastic walls of the cassettes from bowing outward when gels retained within the cassettes swell, as gels typically do during casting, storage, or both. In certain embodiments, these features are incorporated into, or mate with, the comb-shaped inserts that form the sample wells as the gels are being cast. In other embodiments, these features are complementary features incorporated into both the comb and the cassette.

公开(公告)号：AU2012222167A1

公开(公告)日：2013-08-29

申请号：AU2012222167

申请日：2012-02-24

Applicant: BIO RAD LABORATORIES

Inventor： PANATTONI CORY ,  LATHAM MATTHEW ,  KIMMEL KARA ,  WALKER JOHN

IPC: G01N27/26

Abstract: Slab gel cassettes for use in electrophoretic analyses of biologically-derived mixtures are equipped with features that prevent the plastic walls of the cassettes from bowing outward when gels retained within the cassettes swell, as gels typically do during casting, storage, or both. In certain embodiments, these features are incorporated into, or mate with, the comb-shaped inserts that form the sample wells as the gels are being cast. In other embodiments, these features are complementary features incorporated into both the comb and the cassette.