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公开(公告)号：CA2661663A1
公开(公告)日：2008-03-06
申请号：CA2661663
申请日：2007-08-27
Applicant: BIO RAD LABORATORIES
Inventor： VOLKOVA KATERYNA D , KOVALSKA VLADYSLAVA B , LOSYTSKYY MYKHAYLO YU , YARMOLUK SERGIY M , BERKELMAN THOMAS R
IPC: G03F9/00
Abstract: Squaraine dyes are incorporated into a separation medium in which protein or polypeptide mixtures are separated, which medium also contains a deterge nt that forms a complex with the polypeptides or proteins. The dyes, upon ex citation in the separation medium, exhibit a heretofore unrecognized selecti vity in their fluorescent emissions by emitting a signal only when the dye m olecules are associated with complexes of protein (or polypeptide) and deter gent molecules, despite the additional presence of dyes in the bulk of the s eparation medium. The dyes are thus able to indicate the presence and locati ons of proteins or polypeptides in the separation medium without the need fo r removing unassociated dyes from the medium.
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公开(公告)号：DE07814469T1
公开(公告)日：2009-09-03
申请号：DE07814469
申请日：2007-08-27
Applicant: BIO RAD LABORATORIES
Inventor： BERKELMAN THOMAS R , YARMOLUK SERGIY M , KOVALSKA VLADYSLAVA B , LOSYTSKYY MYKHAYLO YU , VOLKOVA KATERYNA D
IPC: G03F9/00
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公开(公告)号：EP2057508A4
公开(公告)日：2010-02-24
申请号：EP07814469
申请日：2007-08-27
Applicant: BIO RAD LABORATORIES
Inventor： BERKELMAN THOMAS R , YARMOLUK SERGIY M , KOVALSKA VLADYSLAVA B , LOSYTSKYY MYKHAYLO YU , VOLKOVA KATERYNA D
CPC classification number: G01N33/6839 , C09B23/0066 , C09B57/007 , G01N2458/30
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