公开(公告)号：CA2808499C

公开(公告)日：2017-06-13

申请号：CA2808499

申请日：2011-08-19

Applicant: BIO-RAD LABORATORIES INC

Inventor： HENG XIN ,  PATT PAUL

IPC: G01N15/10

Abstract: Flow cytometry system includes a flow element through which a cell is transported in a flowing fluid. Flow element includes a bore bounded by a wall. Light source is configured to illuminate the cell. Optical system receives light emanating from the cell and directs at least some of received light to a light sensor. The optical system includes a numerical-aperture-increasing lens at a wall of the flow element. At least some of the received light passes through the numerical-aperture-increasing lens. The flow cytometry system may also include a beam splitter that directs two wavelength bands of emanating light such that light in two wavelength band preferentially reach different sensing locations via different paths. The system may also include an optical element placed in one of the paths, shifting a focal location of the affected path to compensate for chromatic aberration of the numerical-aperture-increasing lens.

公开(公告)号：CA2827726C

公开(公告)日：2017-06-13

申请号：CA2827726

申请日：2012-02-21

Applicant: BIO-RAD LABORATORIES INC

Inventor： HENG XIN ,  PATT PAUL

IPC: G01N15/10

Abstract: Systems and methods for performing cytometry using a linear light sensor. An illumination field, a line scanned by the linear light sensor, or both are swept across a cell to be imaged. Relative motion between the cell and the swept illumination may be created using a movable optical component or components, by adhering cells to a plate and transporting the plate or by other techniques.