公开(公告)号：CA2706681C

公开(公告)日：2017-03-07

申请号：CA2706681

申请日：2002-05-28

Applicant: BIO-RAD LABORATORIES INC

Inventor： BINDER STEVEN R ,  GOODRICH JODI L ,  SAFARIAN ZARA

IPC: G01N33/53 ,  G01N33/573 ,  G01N15/10 ,  G01N33/48 ,  G01N33/96

Abstract: Analyses of serum samples for the presence and amount of either of the two subunits of human Factor XIII protein are used as a means of eliminating a significant source of error that arises in the testing of serum and plasma. For serum samples, a negative result of an analysis for the presence of subunit a is a means of verifying that a sample is indeed serum, while a negative or positive result for subunit a serves to distinguish serum (negative) from plasma (positive). A positive result for the presence of subunit b is a means of verifying that the sample is either serum or plasma and not any other biological fluid. A quantitative analysis of subunit b is a means of verifying that the sample is of the intended volume rather than having been reduced in volume due to improper sampling. A quantitative analysis of subunit b is also a means of verifying the dilution of a sample of either serum or plasma.