公开(公告)号：AU2017274199A1

公开(公告)日：2019-01-03

申请号：AU2017274199

申请日：2017-05-26

Applicant: BOARD OF REGENTS UNIVERSITY OF TEXAS SYSTEM

Inventor： JONES PHILIP ,  CZAKO BARBARA ,  CROSS JASON ,  LEONARD PAUL ,  MSEEH FAIKA ,  PARKER CONNON AUSTIN

IPC: C07D487/04 ,  A61K31/4162 ,  A61K31/4985

Abstract: The present invention relates to compounds which may be useful as inhibitors of PTPN11 for the treatment or prevention of cancer and other PTP-mediated diseases. Disclosed herein are new compounds and compounds based on pyrazolopyrazines and their application as pharmaceuticals for the treatment of disease.