Abstract:
INDOLE IS PREPARED BY THE CATALYTIC DEHYDROGENATION OF 2,3-DIHYDRO INDOLE IN THE PRESENCE OF A PLATINUM OR PALLADIUM CATALYST IN THE ABSENCE OF A HYDROGEN ACCEPTOR.
Abstract:
INDOLE IS PRODUCED IN HIGH YIELDS IN ONE SINGLE STAGE BY CONTACTING GASEOUS 2-(O-NITROPHENYL)-ETHANOL TOGETHER WITH A REDUCING GAS OR A MIXTURE OF REDUCING GAS AND INERT GAS OVER A HYDROGENATION CATALYST HEATED TO A TEMPERATURE OF ABOUT 200 TO 400*C.
WHERE AR AND AR1 ARE PHENYL OR SUBSTITUTED PHENYL ARE COVERTED TO THE CORRESPONDING KETONES WITH NITRIC ACID IN THE PRESENCE OF AN ORGANIC SOLVENT WHICH IS IMMISCIBLE WITH AND RESISTANT TO OXIDATION BY NITRIC ACID.
Abstract:
1,223,399. Aminobenzamide. BOFORS A.B. 21 Jan., 1970 [28 Jan., 1969], No. 3017/70. Heading C2C. o-Aminobenzamide is produced by reacting together o-nitrotoluene and ammonia in the gaseous phase at a temperature exceeding 400‹ C.
Abstract:
1282660 Indole BOFORS AB 14 Oct 1970 [30 Oct 1969] 48871/70 Heading C2C Indole is produced by reacting 2-(o-nitrophenyl)-ethanol in the gaseous phase with hydrogen or ammonia gas, optionally in admixture with an inert gas, at elevated temperature in the presence of a hydrogenation catalyst. Suitable catalysts are, for example, copper, nickel, cobalt, palladium or copper chromite optionally applied to a carrier, for example aluminium oxide or silica gel.
Abstract:
1,205,168. Diaryl ketones. BOFORS A.B. 23 July, 1968 [4 Aug., 1967], No. 35175/68. Heading C2C. 1,2-Diaryl ketones of formula in which Ar and Ar 1 are unsubstituted or substituted phenyl groups are prepared by oxidizing a 1,2-diaryl ethan of formula with nitric acid in the presence of a substantially inert organic solvent which is substantially immiscible with the nitric acid. Suitable solvents are halogenated hydrocarbons, e.g. chloroform. An example is given of the oxidation of 1-phenyl-2-(o-nitrophenyl) ethanol to o-nitrodesoxy benzoin.
Abstract:
1,193,764. Indole. BOFORS A.B. 23 July, 1968 [4 Aug., 1967], No. 35174/68. Heading C2C. 2,3-Dihydro-indole is dehydrogenated by heating at 50-250‹ C. in the presence of a Group VIII noble metal catalyst and an inert organic solvent to give indole. The preferred catalysts are platinum oxide or palladium supported on active carbon and suitable solvents are, for example, toluene, xylene and benzene.
Abstract:
1,201,210. 2-(Nitro-phenyl) alkyl halides. BOFORS A.B. 1 Aug., 1968 [4 Aug., 1967], No. 36833/68. Heading C2C. A method of preparing a 2-(nitrophenyl) alkyl halide comprises halogenating a 2-(nitrophenyl) alkanol with a halogenation agent. Specified halogenation agents include thionyl chlorides, phosphorus tri- and pentachloride, cone. hydrochloric acid, hydriodic acid and phosphorus tribromide or triiodide. Examples describe the preparation of 2-(o-nitrophenyl) ethyl chloride using thionyl chloride or concentrated hydrochloric acid, and of 2-(o-nitrophenyl) ethyl bromide using hydrobromic acid.