公开(公告)号：US20150094493A1

公开(公告)日：2015-04-02

申请号：US14397914

申请日：2013-04-29

Applicant: Bayer MaterialScience AG

Inventor： Michael Merkel ,  Thomas Knauf ,  Cliff Andre Peters ,  Thorsten Schmidt

IPC: C07C209/84

CPC classification number: C07C209/84 ,  C07C211/46 ,  C07C211/50

Abstract: The present invention relates to a method for treating a substance mixture comprising an aromatic amine, wherein the aromatic amine is aniline or 2,4-diaminotoluene, preferably aniline. The substance mixture comprises an aromatic amine and compounds having a higher boiling point than the aromatic amine. The method for treating the substance mixture requires I) separating the first substance mixture by means of distillation in a first distillation unit (110, 1130), to at least partially remove some of the aromatic amine in the process, and to obtain a first bottom product which is removed from the first distillation unit (110, 1130). After removal from the first distillation unit (110, 1130), the bottom product is diluted with a condensed top product from a distillation unit that is different from the first distillation unit and/or with a composition that comprises methanol.

Abstract translation: 本发明涉及一种处理包含芳族胺的物质混合物的方法，其中芳族胺是苯胺或2,4-二氨基甲苯，优选苯胺。 物质混合物包含芳族胺和沸点高于芳族胺的化合物。 用于处理物质混合物的方法需要I）在第一蒸馏单元（110,1130）中通过蒸馏分离第一物质混合物，以至少部分地除去该方法中的一些芳族胺，并获得第一底部 从第一蒸馏单元（110,1130）除去的产物。 从第一蒸馏单元（110,1130）中除去后，用不同于第一蒸馏单元的蒸馏单元和/或包含甲醇的组合物的冷凝顶部产物稀释底部产物。

公开(公告)号：US09290438B2

公开(公告)日：2016-03-22

申请号：US14394139

申请日：2013-04-12

Applicant: Bayer MaterialScience AG

Inventor： Michael Merkel ,  Thomas Knauf ,  Cliff Andre Peters ,  Thorsten Schmidt

IPC: C07C209/36 ,  C07C209/84

CPC classification number: C07C209/36 ,  C07C209/84 ,  Y02P20/584 ,  C07C211/46 ,  C07C211/47

Abstract: The present invention relates to a method of producing aromatic amines by hydrogenation of aromatic nitro compounds. This method provides a reactor containing a hydrogenation catalyst; supplies aromatic nitro compounds and hydrogen to the reactor and contacts them with a hydrogenation catalyst, in which the hydrogen which is supplied to the reactor is by a compressor and the compressor contains an operating fluid which at least partially contacts the hydrogen; and regenerates the hydrogenation catalyst by heating and contacting it with oxygen. Particular operating liquids are subsequently exchanged.

Abstract translation: 本发明涉及通过芳族硝基化合物的氢化生产芳族胺的方法。 该方法提供含有氢化催化剂的反应器; 向反应器中提供芳族硝基化合物和氢气，并与氢化催化剂接触，氢化催化剂中，通过压缩机供给反应器的氢气，压缩机含有至少部分接触氢气的工作流体; 并通过加热和与氧接触来再生氢化催化剂。 随后更换特殊的操作液体。

公开(公告)号：US09284256B2

公开(公告)日：2016-03-15

申请号：US14415794

申请日：2013-07-23

Applicant: Bayer MaterialScience AG

Inventor： Thomas Knauf ,  Michael Merkel

IPC: C07C201/00 ,  C07C201/08 ,  C07C201/16

CPC classification number: C07C201/08 ,  C07C201/16 ,  C07C205/06

Abstract: The present invention provides a continuous process for the production of nitrobenzene by nitration of benzene with mixtures of sulfuric and nitric acid using a stoichiometric excess of benzene, in which the content of aliphatic organic compounds in the feed benzene during the start-up period of the production plant is always maintained at less than 1.5 wt. %, based on the total mass of the feed benzene. This is achieved either by mixing the feed benzene comprising recycled unreacted benzene (recycled benzene) and benzene newly supplied to the reaction (fresh benzene) in appropriate quantitative ratios during the start-up period, depending on the purity of the two streams, or by completely omitting the recycling of unreacted benzene during the start-up period, i.e. the feed benzene consists only of benzene newly supplied to the reaction.

Abstract translation: 本发明提供了一种使用化学计量过量的苯硝化苯与硫酸和硝酸的混合物来生产硝基苯的连续方法，其中在起始时期的进料苯中的脂族有机化合物的含量 生产厂总是维持在1.5重量％以下。 ％，基于进料苯的总质量。 这可以通过在启动期间将包含再循环的未反应苯（再循环苯）和新提供给反应的苯（新鲜苯）的进料苯与合适的定量比例混合，取决于两个流的纯度，或者通过 在启动期间完全省略未反应苯的再循环，即进料苯仅由新提供给反应的苯组成。

公开(公告)号：US20150080611A1

公开(公告)日：2015-03-19

申请号：US14394139

申请日：2013-04-12

Applicant: Bayer MaterialScience AG

Inventor： Michael Merkel ,  Thomas Knauf ,  Cliff Andre Peters ,  Thorsten Schmidt

IPC: C07C209/36

CPC classification number: C07C209/36 ,  C07C209/84 ,  Y02P20/584 ,  C07C211/46 ,  C07C211/47

Abstract: The present invention relates to a method of producing aromatic amines by hydrogenation of aromatic nitro compounds. This method comprises the steps: A) making a reactor containing a hydrogenation catalyst available; B) supplying aromatic nitro compounds and hydrogen to the reactor and contacting them with a hydrogenation catalyst, with at least the hydrogen which is supplied to the reactor is by means of a compressor and the compressor contains an operating fluid which at least partially contacts the hydrogen; and C) regenerating the hydrogenation catalyst by heating and contacting it with oxygen. After step C), steps D1) and/or D2) are carried out. Step D1) removes at least some of any fluids that are present in the reactor and/or in parts of the installation which are fluidically connected to the reactor downstream, with the fluids having been at least partially present in the reactor and/or in these parts of the installation during C).Step D2) at least partially replaces the operating fluid of the compressor which was present in the compressor and/or in recirculation devices connected to the compressor during step C) by an operating fluid which was not present in the compressor and/or in recirculation devices connected to the compressor during step C).

Abstract translation: 本发明涉及通过芳族硝基化合物的氢化生产芳族胺的方法。 该方法包括以下步骤：A）制备含有氢化催化剂的反应器; B）将芳基硝基化合物和氢气供应到反应器中并使其与氢化催化剂接触，至少提供给反应器的氢气是借助于压缩机，并且压缩机包含至少部分地接触氢气的工作流体 ; 和C）通过加热和使其与氧接触来再生氢化催化剂。 在步骤C）之后，执行步骤D1）和/或D2）。 步骤D1）除去反应器和/或在装置的流体连接到反应器下游的部分中的至少一些流体，其中流体至少部分地存在于反应器和/或这些 C）部分安装。 在步骤C）期间，步骤D2）至少部分地替换存在于压缩机中的压缩机的工作流体和/或在步骤C）期间连接到压缩机的再循环装置中的压缩机的工作流体，该工作流体不存在于压缩机和/或再循环装置 在步骤C）中连接到压缩机。

公开(公告)号：US09682917B2

公开(公告)日：2017-06-20

申请号：US14397914

申请日：2013-04-29

Applicant: Bayer MaterialScience AG

Inventor： Michael Merkel ,  Thomas Knauf ,  Cliff Andre Peters ,  Thorsten Schmidt

IPC: C07C209/84

CPC classification number: C07C209/84 ,  C07C211/46 ,  C07C211/50

Abstract: The present invention relates to a method for treating a substance mixture comprising an aromatic amine, wherein the aromatic amine is aniline or 2,4-diaminotoluene, preferably aniline. The substance mixture comprises an aromatic amine and compounds having a higher boiling point than the aromatic amine. The method for treating the substance mixture requires I) separating the first substance mixture by means of distillation in a first distillation unit (110, 1130), to at least partially remove some of the aromatic amine in the process, and to obtain a first bottom product which is removed from the first distillation unit (110, 1130). After removal from the first distillation unit (110, 1130), the bottom product is diluted with a condensed top product from a distillation unit that is different from the first distillation unit and/or with a composition that comprises methanol.

公开(公告)号：US09260377B2

公开(公告)日：2016-02-16

申请号：US14415788

申请日：2013-07-23

Applicant: Bayer MaterialScience AG

Inventor： Thomas Knauf ,  Michael Merkel ,  Antoni Mairata

IPC: C07C201/06 ,  C07C201/08

CPC classification number: C07C201/06 ,  C07C201/08 ,  C07C205/06

Abstract: The invention provides a continuous adiabatic process for the preparation of nitrobenzene by nitrating benzene with mixtures of sulfuric and nitric acids using a stoichiometric excess of benzene, wherein the content of organic compounds in the circulating sulfuric acid, at least during the start-up period of the production plant, is always kept below 1.0 mass percent, based on the total mass of circulating sulfuric acid. This is preferably achieved by a procedure in which, either after the end or before the beginning of a production cycle, the circulating sulfuric acid is circulated at elevated temperature so that the organics contained in the sulfuric acid, preferably comprising nitrobenzene and traces of benzene, dinitrobenzene and nitrophenols, are separated off in the evaporation apparatus for concentrating the sulfuric acid.

Abstract translation: 本发明提供了一种连续的绝热方法，用于通过使用化学计量过量的苯将硫与硝酸的混合物硝化苯来制备硝基苯，其中循环硫酸中有机化合物的含量至少在启动期间 基于循环硫酸的总质量，生产厂总是保持在1.0质量％以下。 这优选通过以下程序来实现，其中，在生产周期结束或开始之前循环硫酸在升高的温度下循环，使得包含在硫酸中的有机物，优选包含硝基苯和痕量的苯， 二硝基苯和硝基苯酚在用于浓缩硫酸的蒸发装置中分离出来。

公开(公告)号：US20150166460A1

公开(公告)日：2015-06-18

申请号：US14415794

申请日：2013-07-23

Applicant: Bayer MaterialScience AG

Inventor： Thomas Knauf ,  Michael Merkel

IPC: C07C201/08 ,  C07C201/16

CPC classification number: C07C201/08 ,  C07C201/16 ,  C07C205/06

Abstract: The present invention provides a continuous process for the production of nitrobenzene by nitration of benzene with mixtures of sulfuric and nitric acid using a stoichiometric excess of benzene, in which the content of aliphatic organic compounds in the feed benzene during the start-up period of the production plant is always maintained at less than 1.5 wt. %, based on the total mass of the feed benzene. This is achieved either by mixing the feed benzene comprising recycled unreacted benzene (recycled benzene) and benzene newly supplied to the reaction (fresh benzene) in appropriate quantitative ratios during the start-up period, depending on the purity of the two streams, or by completely omitting the recycling of unreacted benzene during the start-up period, i.e. the feed benzene consists only of benzene newly supplied to the reaction.

Abstract translation: 本发明提供了一种使用化学计量过量的苯硝化苯与硫酸和硝酸的混合物来生产硝基苯的连续方法，其中在起始时期的进料苯中的脂族有机化合物的含量 生产厂总是维持在1.5重量％以下。 ％，基于进料苯的总质量。 这可以通过在启动期间将包含再循环的未反应苯（再循环苯）和新提供给反应的苯（新鲜苯）的进料苯与合适的定量比例混合，取决于两个流的纯度，或者通过 在启动期间完全省略未反应苯的再循环，即进料苯仅由新提供给反应的苯组成。

公开(公告)号：US09469594B2

公开(公告)日：2016-10-18

申请号：US14394142

申请日：2013-04-12

Applicant: Bayer MaterialScience AG

Inventor： Michael Merkel ,  Thomas Knauf ,  Cliff Andre Peters ,  Thorsten Schmidt ,  Karl-Heinz Wilke

IPC: C07C209/36 ,  C07C209/84

CPC classification number: C07C209/36 ,  C07C209/84 ,  C07C211/46 ,  C07C211/47

Abstract: The present invention relates to a method for producing aromatic amines by the hydrogenation of aromatic nitro compounds. This method supplies aromatic nitro compounds and hydrogen to a reactor and contacts them with a hydrogenation catalyst; and stops the supply of aromatic nitro compounds and hydrogen to the reactor. The supply of aromatic nitro compounds and hydrogen to the reactor is stopped to ensure safe shutdown of the reactor.

Abstract translation: 本发明涉及通过芳族硝基化合物的氢化生产芳族胺的方法。 该方法将芳香族硝基化合物和氢气供给反应器，并与氢化催化剂接触; 并停止向反应器供应芳族硝基化合物和氢气。 停止向反应器供应芳族硝基化合物和氢气，以确保反应器的安全关闭。

公开(公告)号：US20150175522A1

公开(公告)日：2015-06-25

申请号：US14415788

申请日：2013-07-23

Applicant: Bayer MaterialScience AG

Inventor： Thomas Knauf ,  Michael Merkel ,  Antoni Mairata

IPC: C07C201/06

CPC classification number: C07C201/06 ,  C07C201/08 ,  C07C205/06

Abstract: The invention provides a continuous adiabatic process for the preparation of nitrobenzene by nitrating benzene with mixtures of sulfuric and nitric acids using a stoichiometric excess of benzene, wherein the content of organic compounds in the circulating sulfuric acid, at least during the start-up period of the production plant, is always kept below 1.0 mass percent, based on the total mass of circulating sulfuric acid. This is preferably achieved by a procedure in which, either after the end or before the beginning of a production cycle, the circulating sulfuric acid is circulated at elevated temperature so that the organics contained in the sulfuric acid, preferably comprising nitrobenzene and traces of benzene, dinitrobenzene and nitrophenols, are separated off in the evaporation apparatus for concentrating the sulfuric acid.

Abstract translation: 本发明提供了一种连续的绝热方法，用于通过使用化学计量过量的苯将硫与硝酸的混合物硝化苯来制备硝基苯，其中循环硫酸中有机化合物的含量至少在启动期间 基于循环硫酸的总质量，生产厂总是保持在1.0质量％以下。 这优选通过以下程序来实现，其中，在生产周期结束或开始之前循环硫酸在升高的温度下循环，使得包含在硫酸中的有机物，优选包含硝基苯和痕量的苯， 二硝基苯和硝基苯酚在用于浓缩硫酸的蒸发装置中分离出来。

公开(公告)号：US20150087862A1

公开(公告)日：2015-03-26

申请号：US14394142

申请日：2013-04-12

Applicant: Bayer MaterialScience AG

Inventor： Michael Merkel ,  Thomas Knauf ,  Cliff Andre Peters ,  Thorsten Schmidt ,  Karl-Heinz Wilke

IPC: C07C209/36

CPC classification number: C07C209/36 ,  C07C209/84 ,  C07C211/46 ,  C07C211/47

Abstract: The present invention relates to A method for producing aromatic amines by the hydrogenation of aromatic nitro compounds. This method comprises: A) supplying aromatic nitro compounds and hydrogen to a reactor and contacting them with a hydrogenation catalyst; and B) stopping the supply of aromatic nitro compounds and hydrogen to the reactor. In addition, B) is carried out by: B1) stopping the supply of aromatic nitro compounds to the reactor such that any remaining aromatic nitro compounds present in the reactor and/or in parts of the installation that are fluidically connected to the reactor upstream react with the hydrogen that is still being supplied to the reactor, and B2) stopping the supply of hydrogen after a predetermined time interval and/or after the concentration of aromatic nitro compounds in the gas flow entering the reactor falls below a predetermined value.

Abstract translation: 本发明涉及芳香族硝基化合物的氢化制造芳香胺的方法。 该方法包括：A）将芳香族硝基化合物和氢气供给反应器，并与氢化催化剂接触; 和B）停止向反应器供应芳族硝基化合物和氢气。 此外，B）通过以下方式进行：B1）停止向反应器供应芳族硝基化合物，使得存在于反应器中的任何剩余的芳族硝基化合物和/或流体连接到反应器上游的部分设备反应 其中仍然供应到反应器的氢气，以及B2）在预定时间间隔之后和/或在进入反应器的气流中的芳族硝基化合物的浓度之后停止氢气供应降低到预定值以下。